scholarly journals pytc: Open-Source Python Software for Global Analyses of Isothermal Titration Calorimetry Data

Biochemistry ◽  
2018 ◽  
Vol 57 (18) ◽  
pp. 2578-2583 ◽  
Author(s):  
Hiranmayi Duvvuri ◽  
Lucas C. Wheeler ◽  
Michael J. Harms
Keyword(s):  
Open Source ◽  
Isothermal Titration Calorimetry ◽  
Titration Calorimetry ◽  
Calorimetry Data

scholarly journals Titration Calorimetry Standards and the Precision of Isothermal Titration Calorimetry Data

2009 ◽  
Vol 10 (6) ◽  
pp. 2752-2762 ◽  
Author(s):  
Lina Baranauskienė ◽  
Vilma Petrikaitė ◽  
Jurgita Matulienė ◽  
Daumantas Matulis
Keyword(s):  
Isothermal Titration Calorimetry ◽  
Titration Calorimetry ◽  
Calorimetry Data

scholarly journals Re-visiting the trans insertion model for complexin clamping

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Shyam S Krishnakumar ◽  
Feng Li ◽  
Jeff Coleman ◽  
Curtis M Schauder ◽  
Daniel Kümmel ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Isothermal Titration Calorimetry ◽  
Neurotransmitter Release ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Titration Calorimetry ◽  
Nmr Study ◽  
Cross Links ◽  
Calorimetry Data

We have previously proposed that complexin cross-links multiple pre-fusion SNARE complexes via a trans interaction to function as a clamp on SNARE-mediated neurotransmitter release. A recent NMR study was unable to detect the trans clamping interaction of complexin and therefore questioned the previous interpretation of the fluorescence resonance energy transfer and isothermal titration calorimetry data on which the trans clamping model was originally based. Here we present new biochemical data that underscore the validity of our previous interpretation and the continued relevancy of the trans insertion model for complexin clamping.

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