Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors

Lukas Hofmann; Nathan S. Alexander; Wenyu Sun; Jianye Zhang; Tivadar Orban; Krzysztof Palczewski

doi:10.1021/acs.biochem.7b00165

Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors

Biochemistry ◽

10.1021/acs.biochem.7b00165 ◽

2017 ◽

Vol 56 (17) ◽

pp. 2338-2348 ◽

Cited By ~ 2

Author(s):

Lukas Hofmann ◽

Nathan S. Alexander ◽

Wenyu Sun ◽

Jianye Zhang ◽

Tivadar Orban ◽

...

Keyword(s):

Mass Spectrometry ◽

G Protein ◽

G Protein Coupled Receptors ◽

Hydrogen Deuterium Exchange ◽

Extracellular Loop ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Loop 2 ◽

G Protein Coupled

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Effective Application of Bicelles for Conformational Analysis of G Protein-Coupled Receptors by Hydrogen/Deuterium Exchange Mass Spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1007/s13361-015-1083-4 ◽

2015 ◽

Vol 26 (5) ◽

pp. 808-817 ◽

Cited By ~ 39

Author(s):

Nguyen Minh Duc ◽

Yang Du ◽

Thor S. Thorsen ◽

Su Youn Lee ◽

Cheng Zhang ◽

...

Keyword(s):

Mass Spectrometry ◽

Conformational Analysis ◽

G Protein ◽

G Protein Coupled Receptors ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Effective Application ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

G Protein Coupled

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Effective Application of Bicelles for Conformational Analysis of G Protein-Coupled Receptors by Hydrogen/Deuterium Exchange Mass Spectrometry

Biophysical Journal ◽

10.1016/j.bpj.2015.11.2140 ◽

2016 ◽

Vol 110 (3) ◽

pp. 396a

Author(s):

Nguyen Minh Duc ◽

Yang Du ◽

Su-Youn Lee ◽

Cheng Zhang ◽

Brian K. Kobilka ◽

...

Keyword(s):

Mass Spectrometry ◽

Conformational Analysis ◽

G Protein ◽

G Protein Coupled Receptors ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Effective Application ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

G Protein Coupled

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Conformational Analysis of G Protein-Coupled Receptor Signaling by Hydrogen/Deuterium Exchange Mass Spectrometry

Methods in Enzymology - Membrane Proteins—Engineering, Purification and Crystallization ◽

10.1016/bs.mie.2014.12.004 ◽

2015 ◽

pp. 261-278 ◽

Cited By ~ 11

Author(s):

Sheng Li ◽

Su Youn Lee ◽

Ka Young Chung

Keyword(s):

Mass Spectrometry ◽

Conformational Analysis ◽

G Protein ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

G Protein Coupled Receptor ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

G Protein Coupled

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Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques

Metabolic Brain Disease ◽

10.1007/s11011-021-00763-y ◽

2021 ◽

Author(s):

Ahmad Shahir Sadr ◽

Zahra Abdollahpour ◽

Atousa Aliahmadi ◽

Changiz Eslahchi ◽

Mina Nekouei ◽

...

Keyword(s):

Mass Spectrometry ◽

Conformational Changes ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry

Biochemistry ◽

10.1021/acs.biochem.1c00035 ◽

2021 ◽

Author(s):

Patrick S. Merkle ◽

Esben Trabjerg ◽

Song Hongjian ◽

Mathias Ferber ◽

Michel A. Cuendet ◽

...

Keyword(s):

Mass Spectrometry ◽

Major Histocompatibility Complex ◽

T Cell Receptor ◽

Conformational Dynamics ◽

Cell Receptor ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Histocompatibility Complex ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Design and Validation of In-Source Atmospheric Pressure Photoionization Hydrogen/Deuterium Exchange Mass Spectrometry with Continuous Feeding of D2O

Journal of the American Society for Mass Spectrometry ◽

10.1007/s13361-017-1831-8 ◽

2017 ◽

Vol 29 (1) ◽

pp. 85-94 ◽

Cited By ~ 4

Author(s):

Thamina Acter ◽

Seulgidaun Lee ◽

Eunji Cho ◽

Maeng-Joon Jung ◽

Sunghwan Kim

Keyword(s):

Mass Spectrometry ◽

Atmospheric Pressure ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Atmospheric Pressure Photoionization ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Continuous Feeding

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Different conformational dynamics of various active states of β-arrestin1 analyzed by hydrogen/deuterium exchange mass spectrometry

Journal of Structural Biology ◽

10.1016/j.jsb.2015.04.006 ◽

2015 ◽

Vol 190 (2) ◽

pp. 250-259 ◽

Cited By ~ 11

Author(s):

Dong Kyun Kim ◽

Youngjoo Yun ◽

Hee Ryung Kim ◽

Min-Duk Seo ◽

Ka Young Chung

Keyword(s):

Mass Spectrometry ◽

Conformational Dynamics ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Hydrogen deuterium exchange mass spectrometry in biopharmaceutical discovery and development – A review

Analytica Chimica Acta ◽

10.1016/j.aca.2016.08.006 ◽

2016 ◽

Vol 940 ◽

pp. 8-20 ◽

Cited By ~ 36

Author(s):

Bin Deng ◽

Cristina Lento ◽

Derek J. Wilson

Keyword(s):

Mass Spectrometry ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Hydrogen-Deuterium Exchange Mass Spectrometry of Phosphorylation Induced Changes in Smooth Muscle Myosin

Biophysical Journal ◽

10.1016/j.bpj.2012.11.2501 ◽

2013 ◽

Vol 104 (2) ◽

pp. 452a

Author(s):

K. Ilker Sen ◽

Brian D. Haldeman ◽

Richard Brizendine ◽

Roger Mercer ◽

Christine R. Cremo ◽

...

Keyword(s):

Mass Spectrometry ◽

Smooth Muscle ◽

Smooth Muscle Myosin ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Induced Changes ◽

Muscle Myosin

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Deglycosylation induces extensive dynamics changes in α-amylase revealed by hydrogen/deuterium exchange mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.6732 ◽

2013 ◽

Vol 27 (23) ◽

pp. 2625-2630 ◽

Cited By ~ 4

Author(s):

Chengjie Ji ◽

Gary Wei

Keyword(s):

Mass Spectrometry ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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