Reduction of Synthetic Ubiquinone QT Catalyzed by Bovine Mitochondrial Complex I Is Decoupled from Proton Translocation

Biochemistry ◽  
2016 ◽  
Vol 55 (3) ◽  
pp. 470-481 ◽  
Author(s):  
Kenji Okuda ◽  
Masatoshi Murai ◽  
Shunsuke Aburaya ◽  
Wataru Aoki ◽  
Hideto Miyoshi
Keyword(s):  
Complex I ◽  
Proton Translocation ◽  
Mitochondrial Complex I ◽  
Mitochondrial Complex

Accessory subunits of mitochondrial complex I

2013 ◽  
Vol 41 (5) ◽  
pp. 1272-1279 ◽  
Author(s):  
Katarzyna Kmita ◽  
Volker Zickermann
Keyword(s):  
Molecular Mass ◽  
Complex I ◽  
Proton Translocation ◽  
Present Review ◽  
Mitochondrial Complex I ◽  
Mitochondrial Complex ◽  
Cellular Functions ◽  
Accessory Subunits

Mitochondrial complex I has a molecular mass of almost 1 MDa and comprises more than 40 polypeptides. Fourteen central subunits harbour the bioenergetic core functions. We are only beginning to understand the significance of the numerous accessory subunits. The present review addresses the role of accessory subunits for assembly, stability and regulation of complex I and for cellular functions not directly associated with redox-linked proton translocation.

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