Understanding the Link between Lipid Diversity and the Biophysical Properties of the Neuronal Plasma Membrane

Biochemistry ◽  
2020 ◽  
Vol 59 (33) ◽  
pp. 3010-3018
Author(s):  
Katie A. Wilson ◽  
Hugo I. MacDermott-Opeskin ◽  
Eden Riley ◽  
Yiechang Lin ◽  
Megan L. O’Mara
Keyword(s):  
Plasma Membrane ◽  
Biophysical Properties ◽  
Neuronal Plasma Membrane

The role of plasmalogens, Forssman lipids, and sphingolipid hydroxylation in modulating the biophysical properties of the epithelial plasma membrane

2021 ◽  
Vol 154 (9) ◽  
pp. 095101
Author(s):  
Katie A. Wilson ◽  
Stephen J. Fairweather ◽  
Hugo I. MacDermott-Opeskin ◽  
Lily Wang ◽  
Richard A. Morris ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Biophysical Properties

scholarly journals Dynamics and organization of proteins in the neuronal plasma membrane

2020 ◽  
Vol 169 ◽  
pp. 108043 ◽  
Author(s):  
Antoine Triller ◽  
Marianne Renner ◽  
Daniel Choquet
Keyword(s):  
Plasma Membrane ◽  
Neuronal Plasma Membrane

scholarly journals Dynamics of Glycine Receptor Insertion in the Neuronal Plasma Membrane

2001 ◽  
Vol 21 (14) ◽  
pp. 5036-5044 ◽  
Author(s):  
Madelaine Rosenberg ◽  
Jochen Meier ◽  
Antoine Triller ◽  
Christian Vannier
Keyword(s):  
Plasma Membrane ◽  
Glycine Receptor ◽  
Neuronal Plasma Membrane

Chapter 7 Compartmentalizing the Neuronal Plasma Membrane

2008 ◽  
pp. 303-389 ◽  
Author(s):  
Zofia M. Lasiecka ◽  
Chan Choo Yap ◽  
Max Vakulenko ◽  
Bettina Winckler
Keyword(s):  
Plasma Membrane ◽  
Neuronal Plasma Membrane

Composition, biophysical properties, and morphometry of plasma membranes in pulmonary interstitial edema

2002 ◽  
Vol 282 (6) ◽  
pp. L1382-L1390 ◽  
Author(s):  
Paola Palestini ◽  
Chiara Calvi ◽  
Elena Conforti ◽  
Laura Botto ◽  
Carla Fenoglio ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Plasma Membrane ◽  
Plasma Membranes ◽  
Cell Activation ◽  
Membrane Lipids ◽  
Gradient Centrifugation ◽  
Mechanical Stimuli ◽  
Biophysical Properties ◽  
Interstitial Edema ◽  
Vascular Perfusion

We evaluated the changes in plasma membrane composition, biophysical properties, and morphology of pulmonary endothelial cells in anesthetized rabbits receiving 0.5 ml · kg−1 · min−1 saline infusion for 180 min, causing mild interstitial edema. Plasma membrane fractions were obtained from lung homogenates with gradient centrifugation, allowing a sixfold enrichment in caveolin-1. In edematous lungs, cholesterol content and phospholipidic phosphorus increased by 15 and 40%, respectively. These data correlated with morphometric analysis of lungs fixed in situ by vascular perfusion with 2.5% glutaraldehyde, suggesting a relative increase in surface of luminal to interstitial front of the capillary endothelial cells, due to a convoluted luminal profile. In edematous lungs, the fraction of double-bound fatty acids increased in membrane lipids; moreover, the phosphatidylcholine/phosphatidylethanolamine and the cholesterol/phospholipid ratios decreased. These changes were consistent with the increase in fluorescence anisotropy of plasma membrane, indicating an increase in its fluidity. Data suggest that mechanical stimuli elicited by a modest (∼4%) increase in extravascular water cause marked changes in plasma membranes that may be of relevance in signal transduction and endothelial cell activation.

Kir6.1 Is the Principal Pore-Forming Subunit of Astrocyte but Not Neuronal Plasma Membrane K-ATP Channels

2001 ◽  
Vol 18 (6) ◽  
pp. 671-690 ◽  
Author(s):  
Achim Thomzig ◽  
Mareike Wenzel ◽  
Christine Karschin ◽  
Misty J. Eaton ◽  
Serguei N. Skatchkov ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Neuronal Plasma Membrane
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