Determination of the Absolute Amount of Resin-Bound Hydroxyl or Carboxyl Groups for the Optimization of Solid-Phase Combinatorial and Parallel Organic Synthesis

1999 ◽  
Vol 71 (20) ◽  
pp. 4564-4571 ◽  
Author(s):  
Bing Yan ◽  
Lina Liu ◽  
Catherine A. Astor ◽  
Qing Tang
Author(s):  
David R. Bell ◽  
George R. Rossman ◽  
Joachim Maldener ◽  
Denis Endisch ◽  
Friedel Rauch

2004 ◽  
Vol 89 (7) ◽  
pp. 998-1003 ◽  
Author(s):  
David. R. Bell ◽  
George R. Rossman ◽  
Joachim Maldener ◽  
Denis Endisch ◽  
Friedel Rauch

2001 ◽  
Vol 3 (1) ◽  
pp. 85-89 ◽  
Author(s):  
Roland Hany ◽  
Daniel Rentsch ◽  
Boopathy Dhanapal ◽  
Daniel Obrecht

1959 ◽  
Vol XXXII (IV) ◽  
pp. 552-562 ◽  
Author(s):  
Lennart Enerbäck ◽  
Per M. Lundin ◽  
Jan Mellgren

ABSTRACT The effects have been studied in albino rats of experimental stress, adrenalectomy, hypophysectomy and somatotrophin (STH) on the relative serum protein fractions, as determined from estimations of serum protein concentrations and the results of paper electrophoretic separation. In addition, the absolute amounts of serum proteins obtained from concurrent electrophoretic separation, estimation of serum protein concentration and determination of plasma volume were studied. It appeared inter alia that hypophysectomy gave rise to a reduction in the absolute amount of serum proteins, which was due to a reduction in the albumin + alpha1 globulin fraction while the other globulin fractions remained unaffected. STH administration caused an increase in both the albumin and globulin fractions in hypophysectomized rats. Formalin stress was accompanied by changes in the electrophoretic spectrum suggesting an increased globulin synthesis. Since stress is known to give rise to a proliferation of the lymphoid organs which, at least to some extent, is caused by STH we consider it justifiable to conclude that the probable enhancement of globulin synthesis accompanying stress is due to the action of STH.


1932 ◽  
Vol 36 (1) ◽  
pp. 300-311 ◽  
Author(s):  
J. W. McBain ◽  
C. W. Humphreys
Keyword(s):  

Author(s):  
Stuart McKernan ◽  
C. Barry Carter

The determination of the absolute polarity of a polar material is often crucial to the understanding of the defects which occur in such materials. Several methods exist by which this determination may be performed. In bulk, single-domain specimens, macroscopic techniques may be used, such as the different etching behavior, using the appropriate etchant, of surfaces with opposite polarity. X-ray measurements under conditions where Friedel’s law (which means that the intensity of reflections from planes of opposite polarity are indistinguishable) breaks down can also be used to determine the absolute polarity of bulk, single-domain specimens. On the microscopic scale, and particularly where antiphase boundaries (APBs), which separate regions of opposite polarity exist, electron microscopic techniques must be employed. Two techniques are commonly practised; the first [1], involves the dynamical interaction of hoLz lines which interfere constructively or destructively with the zero order reflection, depending on the crystal polarity. The crystal polarity can therefore be directly deduced from the relative intensity of these interactions.


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