Science: Gas-phase separation of biomolecules.

1999 ◽  
Vol 71 (3) ◽  
pp. 85A-85A
Author(s):  
Celia Henry
Keyword(s):  
Phase Separation ◽  
Gas Phase ◽  
Gas Phase Separation

scholarly journals MALDI TIMS IMS of Disialoganglioside Isomers – GD1a and GD1b in Murine Brain Tissue

2021 ◽  
Author(s):  
Katerina Djambazova ◽  
Martin Dufresne ◽  
Lukasz Migas ◽  
Angela Kruse ◽  
Raf Van de Plas ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Phase Separation ◽  
Sialic Acid ◽  
Gas Phase ◽  
Sialic Acid Residue ◽  
Spinal Cord Tissue ◽  
Total Ganglioside ◽  
Tissue Sections ◽  
Maldi Ims ◽  
Gas Phase Separation

Gangliosides are classified as acidic glycosphingolipids, containing ceramide moieties and oligosaccharide chains with one or multiple sialic acid residue(s). The presence of multiple sialylation sites gives rise to highly diverse isomeric structures with distinct biological roles. Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) enables the untargeted spatial analysis of gangliosides, among other biomolecules, directly from tissue sections. Integrating trapped ion mobility mass spectrometry (TIMS), a gas-phase separation technology, with MALDI IMS allows for the investi-gation of isomeric lipid structures in situ. Here we demonstrate the gas-phase separation of disialoganglioside isomers GD1a and GD1b that differ in the position of a sialic acid residue, in a standard mixture of both isomers, a total ganglioside extract, and directly from thin tissue sections. The unique spatial distributions of GD1a/b (d36:1) and GD1a/b (d38:1) were deter-mined from rat hippocampus, as well as in a spinal cord tissue section.

Liquid-Gas Phase Separation in Confined Vibrated Dry Granular Matter

2011 ◽  
Vol 107 (4) ◽  
Author(s):  
Klaus Roeller ◽  
James P. D. Clewett ◽  
R. M. Bowley ◽  
Stephan Herminghaus ◽  
Michael R. Swift
Keyword(s):  
Phase Separation ◽  
Gas Phase ◽  
Granular Matter ◽  
Gas Phase Separation

scholarly journals Gas-phase separation using a trapped ion mobility spectrometer

2011 ◽  
Vol 14 (2-3) ◽  
pp. 93-98 ◽  
Author(s):  
Francisco Fernandez-Lima ◽  
Desmond A. Kaplan ◽  
J. Suetering ◽  
Melvin A. Park
Keyword(s):  
Phase Separation ◽  
Gas Phase ◽  
Ion Mobility ◽  
Ion Mobility Spectrometer ◽  
Trapped Ion ◽  
Gas Phase Separation

Theoretical determination of the gas-gas phase separation in Xe-He

Physica ◽  
1967 ◽  
Vol 33 (2) ◽  
pp. 379-388 ◽  
Author(s):  
P. Zandbergen ◽  
H.F.P. Knaap ◽  
J.J.M. Beenakker
Keyword(s):  
Phase Separation ◽  
Gas Phase ◽  
Theoretical Determination ◽  
Gas Phase Separation

scholarly journals On-line gas-phase separation of short-lived bromine nuclides from precursor selenium

2000 ◽  
Vol 88 (12) ◽  
Author(s):  
M. Wachsmuth ◽  
R. Eichler ◽  
L. Tobler ◽  
D.T. Jost ◽  
H. W. Gäggeler ◽  
...  
Keyword(s):  
Phase Separation ◽  
Thermal Neutron ◽  
Gas Phase ◽  
Nuclear Fission ◽  
On Line ◽  
Gas Phase Separation

Short-lived bromine nuclides, available from thermal neutron induced nuclear fission of

A fluorescence detection scheme for ultra large molecules after gas phase separation

Talanta ◽  
2007 ◽  
Vol 71 (5) ◽  
pp. 2126-2128 ◽  
Author(s):  
J HE ◽  
W ZHONG ◽  
A TANG ◽  
X YAN ◽  
C LEWIS ◽  
...  
Keyword(s):  
Phase Separation ◽  
Gas Phase ◽  
Fluorescence Detection ◽  
Detection Scheme ◽  
Large Molecules ◽  
Gas Phase Separation
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