Recyclable Molecular Trapping and SERS Detection in Silver-Loaded Agarose Gels with Dynamic Hot Spots

2009 ◽  
Vol 81 (22) ◽  
pp. 9233-9238 ◽  
Author(s):  
Paula Aldeanueva-Potel ◽  
Erwan Faoucher ◽  
Ramón A. Alvarez-Puebla ◽  
Luis M. Liz-Marzán ◽  
Mathias Brust
2018 ◽  
Vol 450 ◽  
pp. 138-145 ◽  
Author(s):  
Lili He ◽  
Changqing Liu ◽  
Jia Tang ◽  
Wei Jin ◽  
Hui Yang ◽  
...  

Sensors ◽  
2020 ◽  
Vol 20 (15) ◽  
pp. 4120
Author(s):  
Fei Shao ◽  
Jiaying Cao ◽  
Ye Ying ◽  
Ying Liu ◽  
Dan Wang ◽  
...  

For real application, it is an urgent demand to fabricate stable and flexible surface-enhanced Raman scattering (SERS) substrates with high enhancement factors in a large-scale and facile way. Herein, by using the electrospinning technique, a hydrophobic and flexible poly(styrene-co-butadiene) (SB) fibrous membrane is obtained, which is beneficial for modification of silver nanoparticles (Ag NPs) colloid in a small region and then formation of more “hot spots” by drying; the final SERS substrate is designated as Ag/SB. Hydrophobic Ag/SB can efficiently capture heterocyclic molecules into the vicinity of hot spots of Ag NPs. Such Ag/SB films are used to quantitatively detect trace triazophos residue on fruit peels or in the juice, and the limit of detection (LOD) of 2.5 × 10−8 M is achieved. Ag/SB films possess a capability to resist heat. As a case, 6-mercaptopurine (6MP) that just barely dissolves in 90 °C water is picked for conducting Ag/SB-film-based experiments.


Nanoscale ◽  
2015 ◽  
Vol 7 (18) ◽  
pp. 8619-8626 ◽  
Author(s):  
Xuan He ◽  
Hui Wang ◽  
Zhongbo Li ◽  
Dong Chen ◽  
Jiahui Liu ◽  
...  

Ultra-sensitive ZnO–Ag hybrid SERS substrates are used to detect TNT vapor or solution by a capillarity-constructed reversible hot spots strategy.


2018 ◽  
Vol 10 (26) ◽  
pp. 3215-3223 ◽  
Author(s):  
Carmelo Miccichè ◽  
Giuseppe Arrabito ◽  
Francesco Amato ◽  
Gianpiero Buscarino ◽  
Simonpietro Agnello ◽  
...  

SERS detection of a few alizarin molecules is carried out on hot spots spontaneously generated within low Ohnesorge number picoliter-scale droplets.


NANO ◽  
2018 ◽  
Vol 13 (05) ◽  
pp. 1850053 ◽  
Author(s):  
Hua-Xiang Chen ◽  
Yu-Ting Wang ◽  
Ting-Ting You ◽  
Jin Zhai ◽  
Peng-Gang Yin

Novel surface-enhanced Raman scattering (SERS) substrates with stable and recyclable properties have been prepared by assembling gold nanoparticles-loaded PET (AuNPs/PET) nanocomposite superhydrophobic surfaces. After a physical vapor deposition process, the AuNPs/PET surfaces with vast plasmonic “hot spots” showed superhydrophobic properties, and it can hold target molecules droplets for rapid SERS detection. From blown off droplets and rinsed substrates with water after detection, we found that no probe molecules remained on the surfaces from Raman spectra. The prepared substrates were not contaminated in the detection process. Furthermore, the new SERS substrates were used for rapidly detecting droplets of crystal violet (CV) and the lowest detection concentration was about [Formula: see text] M. The as-prepared AuNPs/PET substrates also have good performance in terms of reproducibility and recyclability.


2008 ◽  
Vol 112 (20) ◽  
pp. 7527-7530 ◽  
Author(s):  
Luca Guerrini ◽  
José V. Garcia-Ramos ◽  
Concepción Domingo ◽  
Santiago Sanchez-Cortes

Author(s):  
Antonino Foti ◽  
Cristiano D'andrea ◽  
Valentina Villari ◽  
Norberto Micali ◽  
Maria Grazia Donato ◽  
...  

Optical forces are used to aggregate plasmonic nanoparticles and create SERS-active hot spots in liquid. When biomolecules are added to the nanoparticles, high sensitivity SERS detection is accomplished. Here we tailor this methodology to detect catalase and hemoglobin, two Raman resonant biomolecules, at concentrations down to 10 nM and 1 pM. Subsequently, we study the SERS signal in Bovine Serum Albumin as a function of the concentration, finding a monotonic dependence that suggests the possibility of quantitative detection. Finally, by exploiting nanoparticles functionalized with specific aptamers, we obtain first results on the SERS detection of Ochratoxin A, a fungal toxin found in food commodities and wine. This represents a first step towards the addition of molecular specificity to this novel biosensor strategy.


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