Advantages of Molecularly Imprinted Polymers LC-ESI-MS/MS for the Selective Extraction and Quantification of Chloramphenicol in Milk-Based Matrixes. Comparison with a Classical Sample Preparation

2007 ◽  
Vol 79 (24) ◽  
pp. 9557-9565 ◽  
Author(s):  
Rayane Mohamed ◽  
Janique Richoz-Payot ◽  
Eric Gremaud ◽  
Pascal Mottier ◽  
Ecevit Yilmaz ◽  
...  
Author(s):  
Haley A Mulder ◽  
Matthew S Halquist

Abstract In the world of forensic and clinical toxicology, proper sample preparation is one of the key steps in identification and quantification of drugs of abuse. Traditional extraction methods such as solid-phase extraction and liquid−liquid extraction are often laborious and nonselective for the target analytes being measured. Molecularly imprinted polymers (MIPs) can be synthesized for sample extraction and their versatility allows the polymer to be employed in off-line, benchtop extractions or on/in-line instrument extractions, offering a faster and more selective sample preparation without the risk of interfering matrix effects. This review details the synthesis and applications of MIP materials for the extraction of drug compounds from biological matrices in publications from 1994 to today.


2014 ◽  
Vol 6 (16) ◽  
pp. 6397-6406 ◽  
Author(s):  
Xiaoyan Li ◽  
Mei Li ◽  
Junjie Li ◽  
Fuhou Lei ◽  
Xiaomeng Su ◽  
...  

A novel sample clean-up technique, i.e., molecularly imprinted solid-phase extraction (MISPE) combined with HPLC, was developed and validated for the selective extraction and determination of basic orange II in foods.


2011 ◽  
Vol 402 (3) ◽  
pp. 1337-1346 ◽  
Author(s):  
Jie-Ping Fan ◽  
Lu Zhang ◽  
Xue-Hong Zhang ◽  
Jun-zhong Huang ◽  
Sheng Tong ◽  
...  

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