Identification of heroin and its diluents by chemical ionization mass spectroscopy

1974 ◽  
Vol 46 (2) ◽  
pp. 296-298 ◽  
Author(s):  
Jew-Ming. Chao ◽  
Richard. Saferstein ◽  
John. Manura
Keyword(s):  
Mass Spectroscopy ◽  
Chemical Ionization ◽  
Ionization Mass ◽  
Ionization Mass Spectroscopy

scholarly journals Development of a photochemical source for the production and calibration of acyl peroxynitrate compounds

2015 ◽  
Vol 8 (5) ◽  
pp. 2225-2231 ◽  
Author(s):  
P. R. Veres ◽  
J. M. Roberts
Keyword(s):  
Dynamic System ◽  
Mass Spectroscopy ◽  
Chemical Ionization ◽  
Acyl Chloride ◽  
Ionization Mass ◽  
Gas Chromatograph ◽  
Iodide Ion ◽  
Ionization Mass Spectroscopy ◽  
Subsequent Separation ◽  
Standard Production

Abstract. A dynamic system for the calibration of acyl peroxynitrate compounds (APNs) has been developed in the laboratory to reduce the difficulty, required time, and instability of laboratory-produced standards for difficult-to-synthesize APN species. In this work we present a photochemical source for the generation of APN standards: acetyl peroxynitrate (PAN), propionyl peroxynitrate (PPN), acryloyl peroxynitrate (APAN), methacryloyl peroxynitrate (MPAN), and crotonyl peroxynitrate (CPAN). APNs are generated via photolysis of a mixture of acyl chloride (RC(O)Cl) and ketone (RC(=O)R) precursor compounds in the presence of O2 and NO2. Subsequent separation by a prep-scale gas chromatograph and detection with a total NOy instrument serve to quantify the output of the APN source. Validation of the APN products was performed using iodide ion chemical ionization mass spectroscopy (I- CIMS). This method of standard production is an efficient and accurate technique for the calibration of instrumentation used to measure PAN, PPN, APAN, MPAN, and CPAN.

Identification of Drugs by Chemical Ionization Mass Spectroscopy

1973 ◽  
Vol 56 (5) ◽  
pp. 1234-1238 ◽  
Author(s):  
Richard Saferstein ◽  
Jew-Ming Chao
Keyword(s):  
Mass Spectroscopy ◽  
Chemical Ionization ◽  
Ionization Mass ◽  
Molecular Ion ◽  
Ionization Mass Spectroscopy ◽  
Abused Drugs

Abstract Methods of identifying drugs by chemical ionization (Cl) mass spectroscopy have been investigated. This type of ionization is accomplished by the reaction of the drug with either ionized gaseous methane or isobutane. The resulting spectrum is less complex than that produced by conventional mass spectroscopy and usually results in the formation of a molecular ion plus one (M + 1). The isobutane CI spectra of 62 commonly abused drugs were determined. The mechanism for the formation of fragmentation ions is discussed.

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