Determination of active hydrogen in organic compounds by chemical ionization mass spectrometry

1972 ◽  
Vol 44 (7) ◽  
pp. 1292-1294 ◽  
Author(s):  
Donald F. Hunt ◽  
Charles N. McEwen ◽  
R. A. Upham
1983 ◽  
Vol 10 (8) ◽  
pp. 480-484 ◽  
Author(s):  
J. J. Keyzer ◽  
H. Breukelman ◽  
H. Elzinga ◽  
B. J. Koopman ◽  
B. G. Wolthers ◽  
...  

1982 ◽  
Vol 28 (1) ◽  
pp. 174-177 ◽  
Author(s):  
C Lindberg ◽  
S Jönsson ◽  
P Hedner ◽  
A Gustafsson

Abstract We describe a method for determination of cortisol in plasma and urine, based on chemical ionization/mass spectrometry with deuterium-labeled cortisol as the internal standard. The within-run precision (CV) was 2.5-5.7%, the between-run precision 4.6%. Results by this method were compared with those by a radioimmunological method (RIANEN Cortisol, New England Nuclear) for 395 plasma samples. The latter method gave significantly higher (approx. 25%) cortisol values.


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