Stability Studies on Ferric Thiocyanate Complex as Used for Determination of Micro Amounts of Chloride.

1966 ◽  
Vol 38 (1) ◽  
pp. 145-147 ◽  
Author(s):  
H. N. Elsheimer ◽  
R. L. Kochen
Keyword(s):  
Stability Studies ◽  
Thiocyanate Complex ◽  
Ferric Thiocyanate

scholarly journals Original Research Article Investigation of Antioxidant Potential in Ocimum basilicum Flower

2021 ◽  
pp. 56-64
Author(s):  
Sadaf Khurshid Kayani
Keyword(s):  
Antioxidant Capacity ◽  
Column Chromatography ◽  
Antioxidant Properties ◽  
Ocimum Basilicum ◽  
Original Research ◽  
Thiocyanate Complex ◽  
Dark Bottle ◽  
Phenolic Contents ◽  
Ferric Thiocyanate

Aims: The present work is particularly focused on antioxidant properties of flower of Ocimum basilicum plant. Study Design: Study is basically designed on Column chromatography of extracts. Place and Duration of Study: Sample collection and all experimental work was done in Chemistry Department Government College University, Lahore. The study comprises duration of 6 months. Methodology: The flower of Ocimum basilicum were collected, dried and grinded. It was soaked in methanol-water (70:30) in dark bottle for a week. Followed by a scheme (column chromatography). After TLC of extracts, three activities were done. Phosphomolybdate, Ferric thiocyanate (FTC), and Folin-Ciocalteu (FC reagent) for determination of antioxidant capacity, peroxidation, determination of total phenols respectively. Results: The sample OC2 and crude have maximum absorbance at the concentration of 100µl, 200µl and 300µl. The results show that crude has maximum antioxidant capacity. The phenolic contents are in the increasing order of fraction OC2, OC5, and crude. The maximum phenolic contents are present in crude. Reference has the maximum ability for peroxidation for ferric thiocyanate complex by giving red colour. Conclusion: Overall it is concluded that Ocimum basilicum flower has antioxidant capacity as good as a standard antioxidant. It is recommended in food/medicine as natural herbal product.

Determination of Hydroperoxides in Rubber and Synthetic Polymers

1947 ◽  
Vol 20 (1) ◽  
pp. 45-54
Author(s):  
H. A. Laitinen ◽  
J. S. Nelson
Keyword(s):  
Acid Solution ◽  
Ferrous Iron ◽  
Synthetic Polymers ◽  
Colorimetric Determination ◽  
Thiocyanate Complex ◽  
Styrene Copolymer ◽  
Ferric Thiocyanate ◽  
Ferric Salt ◽  
Butadiene Styrene

Abstract Ferrous iron has been used as a reagent for the determination of peroxide by numerous investigators. Yule and Wilson estimated peroxide in cracked gasoline by shaking with an acid solution of ferrous thiocyanate and back-titrating the resulting ferric salt with titanous chloride. The method was criticized by Young, Vogt, and Nieuwland, who used the color of the resulting ferric thiocyanate complex as a basis for a colorimetric determination of peroxide. In this procedure methanol was used as the solvent. Bolland, Sundralingam, Sutton and Tristram modified the method to enable rubber samples to be analyzed by changing the solvent to a mixture of benzene and methanol (73 per cent benzene by volume). For determining peroxide in GR-S (butadiene-styrene copolymer) and other butadiene copolymers it would be desirable to employ a solvent rich in benzene, since these polymers tend towards insolubility upon oxidation. A solvent composed largely of benzene would also improve the sensitivity of the determination, since larger quantities of polymer could be dissolved in a given volume of solvent.

The extraction and determination of molybdenum as the thiocyanate complex

1962 ◽  
Vol 26 ◽  
pp. 363-370 ◽  
Author(s):  
J.O. Hibbits ◽  
R.T. Williams
Keyword(s):  
Thiocyanate Complex

scholarly journals Simultaneous Determination and Stability Studies on Diminazene Diaceturate and Phenazone Using Developed Derivative Spectrophotometric Method

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ruaa Mohamed Akode ◽  
Shaza Wagiealla Shantier ◽  
Elrasheed Ahmed Gadkariem ◽  
Magdi Awadalla Mohamed
Keyword(s):  
Simultaneous Determination ◽  
Correlation Coefficients ◽  
Degradation Process ◽  
Stability Studies ◽  
Temperature Dependent ◽  
First Order Kinetics ◽  
First Derivative Spectrophotometry ◽  
Aqueous Mixture ◽  
Photo Stability

This work presents UV first derivative spectrophotometry as a precise, accurate, and feasible method for simultaneous determination of diminazene diaceturate and phenazone in bulk and dosage forms. The absorbance values of diminazene diaceturate and phenazone aqueous mixture were obtained at 398 nm and 273 nm, respectively. The developed method was proved to be linear over the concentration ranges (2–10) μg/mL and (2.496–12.48) μg/mL for diminazene diaceturate and phenazone, respectively, with good correlation coefficients (not less than 0.997). The detection and quantitation limits were found to be (LOD = 0.63 and 0.48 μg/mL; LOQ = 1.92 and 1.47 μg/mL, resp.). The developed method was employed for stability studies of both drugs under different stress conditions. Diminazene diaceturate was prone to degrade at acidic pH via first-order kinetics. The degradation process was found to be temperature dependent with an activation energy of 7.48 kcal/mole. Photo-stability was also investigated for this drug.

scholarly journals Spectrofluorometric Determination of Verapamil Hydrochloride in Pharmaceutical Preparations and Human Plasma Using Organized Media: Application to Stability Studies

2006 ◽  
Vol 89 (6) ◽  
pp. 1565-1572 ◽  
Author(s):  
Mohamed Walash ◽  
Fathalla Belal ◽  
Nahed El-Enany ◽  
Amina Abdelsalam
Keyword(s):  
Human Plasma ◽  
Biological Fluids ◽  
Sodium Dodecyl ◽  
Pharmaceutical Preparations ◽  
Pharmaceutical Formulations ◽  
Official Method ◽  
Stability Studies ◽  
Verapamil Hydrochloride ◽  
Spiked Human Plasma

Abstract A highly sensitive spectrofluorometric method was developed for the determination of verapamil hydrochloride (VP HCl) in pharmaceutical formulations and biological fluids. The proposed method is based on investigation of the fluorescence spectral behavior of VP HCl in micellar systems, such as sodium dodecyl sulfate (SDS) and β-cyclodextrin (β-CD). In aqueous solutions of borate buffer of pH 9 and 8.5, VP HCl was well incorporated into SDS and β-CD, respectively, with enhancement of its native fluorescence. The fluorescence was measured at 318 nm after excitation at 231 nm. The fluorescence intensity enhancements were 183 and 107% in SDS and in β-CD, respectively. The fluorescence-concentration plots were rectilinear over the range of 0.020.2 and 0.020.25 μg/mL, with lower detection limits of 5.58 × 103 and 3.62 × 103 μg/mL in SDS and β-CD, respectively. The method was successfully applied to the analysis of commercial tablets and the results were in good agreement with those obtained with the official method. The method was further applied to the determination of VP HCl in real and spiked human plasma. The mean % recoveries in the case of spiked human plasma (n 4) was 92.59 3.11 and 88.35 2.55 using SDS and β-CD, respectively, while that in real human plasma (n 3) was 90.17 6.93 and 89.17 6.50 using SDS and β-CD, respectively. The application of the method was extended to the stability studies of VP HCl after exposureto ultraviolet radiation and upon oxidation with hydrogen peroxide.

Sign in / Sign up

Export Citation Format

Share Document