Study of Accuracy in Chemical Analysis Using Linear Calibration Curves

1957 ◽  
Vol 29 (5) ◽  
pp. 743-749 ◽  
Author(s):  
John. Mandel ◽  
F. J. Linning
Keyword(s):  
Chemical Analysis ◽  
Linear Calibration ◽  
Calibration Curves

Electrospray Mass Spectrometry as a Technique for Elemental Analysis: Quantitative Aspects

1994 ◽  
Vol 48 (6) ◽  
pp. 649-654 ◽  
Author(s):  
George R. Agnes ◽  
Gary Horlick
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
Dynamic Range ◽  
Internal Standard ◽  
Linear Calibration ◽  
Constant Amount ◽  
Factors Affecting ◽  
Analyte Signal ◽  
Calibration Curves ◽  
Electrospray Process

The quantitative aspects of elemental electrospray mass spectrometry are investigated with particular emphasis on the factors affecting the ability to establish linear calibration curves. It is shown that linear calibration curves can be obtained for trace elements if the analyte signal is ratioed to the signal from a constant amount of a similarly charged electrolyte species. Linear calibration curves can be established over a concentration dynamic range of at least four orders of magnitude. The added component seems to function as a stabilizer and monitor of the electrospray process and as an internal standard. In certain cases, species generated by acidification of the solvent may be used as electrospray stabilizers.

The Dynamic Calibration of Tipping-Bucket Raingauges

1986 ◽  
Vol 17 (3) ◽  
pp. 203-214 ◽  
Author(s):  
Janusz Niemczynowicz
Keyword(s):  
Rainfall Intensity ◽  
Nordic Countries ◽  
Dynamic Calibration ◽  
Calibration Function ◽  
Linear Calibration ◽  
Calibration Curves ◽  
Non Linear ◽  
Rainfall Volume

The dynamic calibration of three types of tipping-bucket raingauges extensively used in the Nordic countries was performed. The tested and calibrated gauges were: “LTH gauge”, PLUMATIC gauge and RIMCO gauge. It was found that with regard to all tested gauges, the volume of water which tips the bucket is not a constant characteristic for the gauge; it depends on rainfall intensity. Thus, in order to avoid errors, a calculation of the rainfall intensity or of rainfall volume from tipping-bucket registrations must go through empirical, usually non-linear calibration function. The procedure involved in the dynamic calibration of the tipping-bucket raingauges is described in the paper. Examples of typical calibration curves are provided. The magnitude of errors, in respect of measured rainfall intensity, which occur when linear gauge calibration is used is stated too.

Practical Applications of Radioimmunoassay Theory. A Simple Procedure Yielding Linear Calibration Curves

1975 ◽  
Vol 21 (8) ◽  
pp. 1113-1120 ◽  
Author(s):  
Alberto A Fernandez ◽  
Harold G Loeb
Keyword(s):  
Control Function ◽  
Simple Procedure ◽  
Fundamental Equation ◽  
Ligand Concentration ◽  
Linear Calibration ◽  
Equilibrium Conditions ◽  
Practical Applications ◽  
Calibration Curves ◽  
Assay Conditions

Abstract The fundamental equation describing radioimmunoassays under equilibrium conditions has been recast into a "working equation" in a form more directly applicable to the requirements of the analytical laboratory. Plotting total counts over counts bound vs. ligand concentration, which is conveniently linear over most of its course, is shown readily to yield quantitative data relative to binding site concentration and the equilibrium constant and to provide a means for deriving apparent labeled ligand concentration. Such data are helpful in establishing optimum assay conditions and can serve a continuing quality-control function. The working equation also characterizes the binder and tracer reagents used in the assay. The determination of working-equation parameters has been illustrated for the vitamin B12 assay. Data are presented for seven different assay procedures, involving more than 600 calibration curves and 100 different lots of binding agent and tracer reagent, showing a Consistently High Correlation Coefficient (R> 0.990), between ligand concentration and the response variable.

Potential error in single-point-ratio calculations based on linear calibration curves with a significant intercept

1980 ◽  
Vol 52 (8) ◽  
pp. 1187-1191 ◽  
Author(s):  
Mario J. Cardone ◽  
Philip J. Palermo ◽  
Larry B. Sybrandt
Keyword(s):  
Single Point ◽  
Linear Calibration ◽  
Potential Error ◽  
Calibration Curves

scholarly journals New Telemetry Device for the Measurement of Gastrointestinal Motility in Rats and Comparison With Standard Equipment

2015 ◽  
Vol 100 (4) ◽  
pp. 755-760
Author(s):  
Tobias Meile ◽  
Derek Zieker ◽  
Alfred Königsrainer ◽  
Jörg Glatzle
Keyword(s):  
Gastrointestinal Motility ◽  
Strain Gauge ◽  
Linear Calibration ◽  
Standard Equipment ◽  
Freely Moving Rats ◽  
Calibration Curves ◽  
Significant Difference ◽  
Freely Moving

To perform stress-free recording of gastrointestinal motility in rats with strain gauge transducers, telemetry equipment had to be developed. We developed, programmed, and tested a new telemetry device that records gastrointestinal motility in freely moving rats using strain gauge transducers. The device can collect and transmit data in freely moving rats. Data are received and stored for later analysis with a regular PC. Linear calibration curves were obtained for the strain gauge transducers used. We compared data obtained with the new telemetry device with data gathered with standard equipment and could not find any statistically significant difference. Wired gastric and colonic contraction frequencies were 4.6 ± 0.3 per minute and 1.5 ± 0.3 per minute, whereas telemetric contraction frequencies were 4.4 ± 0.1 per minute and 1.25 ± 0.1 per minute. The new telemetry device is a very useful tool for the measurement of gastrointestinal motility in rats.

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