Colorimetric Method for Determination of Traces of Carbon Dioxide in Air

1947 ◽  
Vol 19 (1) ◽  
pp. 55-58 ◽  
Author(s):  
N. A. Spector ◽  
B. F. Dodge
1961 ◽  
Vol 39 (2) ◽  
pp. 287-295 ◽  
Author(s):  
V. R. Woodford ◽  
Nel Leegwater ◽  
S. M. Drance

A modification of a colorimetric method for the determination of carbonic anhydrase is described in which substrate is supplied in the form of gaseous carbon dioxide. Using this method, the inhibitory effects of seven carbonic anhydrase inhibitors used in the control of intraocular pressure were investigated. It was found that equilibrium between enzyme and inhibitor required from 2 minutes to 64 minutes to become established. A comparison of the inhibitory potencies of the various drugs is presented.


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