scholarly journals Data Size Reduction Strategy for the Classification of Breath and Air Samples Using Multicapillary Column-Ion Mobility Spectrometry

2015 ◽  
Vol 87 (2) ◽  
pp. 869-875 ◽  
Author(s):  
Ewa Szymańska ◽  
Emma Brodrick ◽  
Mark Williams ◽  
Antony N. Davies ◽  
Henk-Jan van Manen ◽  
...  
Keyword(s):  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Size Reduction ◽  
Air Samples ◽  
Reduction Strategy ◽  
Multicapillary Column

Detection and classification of explosive compounds utilizing laser ion mobility spectrometry

2009 ◽  
Author(s):  
A. Langmeier ◽  
W. Heep ◽  
C. Oberhuettinger ◽  
H. Oberpriller ◽  
M. Kessler ◽  
...  
Keyword(s):  
Ion Mobility Spectrometry ◽  
Ion Mobility

scholarly journals Erratum to: Separation and Classification of Lipids Using Differential Ion Mobility Spectrometry

2011 ◽  
Vol 22 (7) ◽  
pp. 1156-1156
Author(s):  
Alexandre A. Shvartsburg ◽  
Giorgis Isaac ◽  
Nathalie Leveque ◽  
Richard D. Smith ◽  
Thomas O. Metz
Keyword(s):  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Differential Ion Mobility Spectrometry

Classification of Field Asymmetric Ion Mobility Spectrometry Data for Detection of Bowel Bacteria

2012 ◽  
Author(s):  
Julian W. Gardner ◽  
James McIntosh ◽  
Natalie Ouaret ◽  
Peter Gold ◽  
Chuka Nwokolo ◽  
...  
Keyword(s):  
Ion Mobility Spectrometry ◽  
Ion Mobility

scholarly journals Headspace Gas Chromatography Coupled to Mass Spectrometry and Ion Mobility Spectrometry: Classification of Virgin Olive Oils as a Study Case

Foods ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1288
Author(s):  
María García-Nicolás ◽  
Natalia Arroyo-Manzanares ◽  
Lourdes Arce ◽  
Manuel Hernández-Córdoba ◽  
Pilar Viñas
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Olive Oil ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
External Validation ◽  
Headspace Gas Chromatography ◽  
Validation Rate ◽  
Headspace Gas

Due to its multiple advantages, ion mobility spectrometry (IMS) is being considered as a complementary technique to mass spectrometry (MS). The goal of this work is to investigate and compare the capacity of IMS and MS in the classification of olive oil according to its quality. For this purpose, two analytical methods based on headspace gas chromatography (HS-GC) coupled with MS or with IMS have been optimized and characterized for the determination of volatile organic compounds from olive oil samples. Both detectors were compared in terms of sensitivity and selectivity, demonstrating that complementary data were obtained and both detectors have proven to be complementary. MS and IMS showed similar selectivity (10 out of 38 compounds were detected by HS-GC-IMS, whereas twelve compounds were detected by HS-GC-MS). However, IMS presented slightly better sensitivity (Limits of quantification (LOQ) ranged between 0.08 and 0.8 µg g−1 for HS-GC-IMS, and between 0.2 and 2.1 µg g−1 for HS-GC-MS). Finally, the potential of both detectors coupled with HS-GC for classification of olive oil samples depending on its quality was investigated. In this case, similar results were obtained when using both HS-GC-MS and HS-GC-IMS equipment (85.71 % of samples of the external validation set were classified correctly (validation rate)) and, although both techniques were shown to be complementary, data fusion did not improve validation results (80.95% validation rate).

On-line headspace-multicapillary column-ion mobility spectrometry hyphenation as a tool for the determination of off-flavours in foods

2014 ◽  
Vol 1333 ◽  
pp. 99-105 ◽  
Author(s):  
Isabel Márquez-Sillero ◽  
Soledad Cárdenas ◽  
Stefanie Sielemann ◽  
Miguel Valcárcel
Keyword(s):  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
On Line ◽  
Multicapillary Column

Detection of malignant pleural mesothelioma in exhaled breath by multicapillary column/ion mobility spectrometry (MCC/IMS)

2016 ◽  
Vol 10 (4) ◽  
pp. 046001 ◽  
Author(s):  
Kevin Lamote ◽  
Matthijs Vynck ◽  
Joris Van Cleemput ◽  
Olivier Thas ◽  
Kristiaan Nackaerts ◽  
...  
Keyword(s):  
Malignant Pleural Mesothelioma ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Pleural Mesothelioma ◽  
Exhaled Breath ◽  
Multicapillary Column

scholarly journals Rapid non- invasive detection of Influenza- A- infection by multicapillary column coupled ion mobility spectrometry

2020 ◽  
Author(s):  
Claus Steppert ◽  
Isabel Steppert ◽  
Thomas Bollinger ◽  
William Sterlacci
Keyword(s):  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Influenza A ◽  
Viral Infections ◽  
Multivariate Statistical ◽  
Infected People ◽  
Staff Members ◽  
Number Of Patients ◽  
Registration Number ◽  
Multicapillary Column

Infectious pathogens are a global issue. Global air travelling offers an easy and fast opportunity not only for people but also for infectious diseases to spread around the world within a few days. Also, large public events facilitate increasing infection numbers. Therefore, a rapid on-site screening for infected people is urgently needed. Due to the small size and easy handling, the ion mobility spectrometry coupled with a multicapillary column (MCC-IMS) is a very promising, sensitive method for the on-site identification of infectious pathogens based on scents, representing volatile organic compounds (VOCs). The purpose of this study was to prospectively assess whether identification of Influenza-A- infection based on VOCs by MCC-IMS is possible in breath. Nasal breath was investigated in 24 consecutive persons with and without Influenza-A-infection by MCC-IMS. In 14 Influenza-A-infected patients, infection was proven by PCR of nasopharyngeal swabs. Four healthy staff members and six patients with negative PCR result served as controls. For picking up relevant VOCs in MCC-IMS spectra, software based on cluster analysis followed by multivariate statistical analysis was applied. With only four VOCs canonical discriminant analysis was able to distinguish Influenza-A-infected patients from not infected with 100% sensitivity and 100% specificity. This present proof-of-concept- study yields encouraging results showing a rapid diagnosis of viral infections in nasal breath within 5 minutes by MCC-IMS. The next step is to validate the results with a greater number of patients with Influenza-A-infection as well as other viral diseases, especially COVID-19. Registration number at ClinicalTrials.gov NCT04282135.

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