scholarly journals High-Throughput Thermal Stability Analysis of a Monoclonal Antibody by Attenuated Total Reflection FT-IR Spectroscopic Imaging

2014 ◽  
Vol 86 (19) ◽  
pp. 9786-9793 ◽  
Author(s):  
Maxime Boulet-Audet ◽  
Bernadette Byrne ◽  
Sergei G. Kazarian
2010 ◽  
Vol 66 (a1) ◽  
pp. s294-s295
Author(s):  
Naomi E. Chayen ◽  
Lata Govada ◽  
K. L. Andrew Chan ◽  
Roslyn M. Bill ◽  
Sergei G. Kazarian

2009 ◽  
Vol 81 (10) ◽  
pp. 3769-3775 ◽  
Author(s):  
K. L. Andrew Chan ◽  
Lata Govada ◽  
Roslyn M. Bill ◽  
Naomi E. Chayen ◽  
Sergei G. Kazarian

2016 ◽  
Vol 89 (2) ◽  
pp. 1283-1289 ◽  
Author(s):  
Francesca Gabrieli ◽  
Francesca Rosi ◽  
Alessandra Vichi ◽  
Laura Cartechini ◽  
Luciano Pensabene Buemi ◽  
...  

2014 ◽  
Vol 68 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Ian P. Silverwood ◽  
Colin W. Keyworth ◽  
Neil J. Brown ◽  
Milo S.P. Shaffer ◽  
Charlotte K. Williams ◽  
...  

2009 ◽  
Vol 63 (5) ◽  
pp. 512-517 ◽  
Author(s):  
Jean-Michel Andanson ◽  
K. L. Andrew Chan ◽  
Sergei G. Kazarian

Infrared (IR) spectroscopy has been successfully applied to study the permeation of substances through human skin in a high-throughput manner. The sample of skin was placed on the measuring surface of an attenuated total reflection (ATR) crystal and was divided into several areas. These areas were separated using a specially designed grid created on the surface of the skin and each area was subjected to a different combination of permeant and enhancer. ATR Fourier transform infrared (FT-IR) imaging was applied to measure the permeation of 12 liquid samples through a piece of skin smaller than 5 cm2. This work demonstrated that, using the ATR-FT-IR imaging method, it is possible to measure and directly compare the transdermal processes of several permeants under identical conditions.


2008 ◽  
Vol 80 (8) ◽  
pp. 2957-2962 ◽  
Author(s):  
Joerg Sorber ◽  
Gerald Steiner ◽  
Volker Schulz ◽  
Margarita Guenther ◽  
Gerald Gerlach ◽  
...  

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