Enhanced Enzymatic Reactivity for Electrochemically Driven Drug Metabolism by Confining Cytochrome P450 Enzyme in TiO2 Nanotube Arrays

2014 ◽  
Vol 86 (15) ◽  
pp. 8003-8009 ◽  
Author(s):  
Jusheng Lu ◽  
Henan Li ◽  
Dongmei Cui ◽  
Yuanjian Zhang ◽  
Songqin Liu
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Tio2 Nanotube Arrays ◽  
Tio2 Nanotube ◽  
Nanotube Arrays ◽  
Cytochrome P450 Enzyme ◽  
P450 Enzyme

Cytochrome P450 enzyme functionalized-quantum dots as photocatalysts for drug metabolism

2014 ◽  
Vol 50 (57) ◽  
pp. 7607-7610 ◽  
Author(s):  
Xuan Xu ◽  
Jing Qian ◽  
Jiachao Yu ◽  
Yuanjian Zhang ◽  
Songqin Liu
Keyword(s):  
Quantum Dots ◽  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Cytochrome P450 Enzyme ◽  
Cytochrome P450 2C9 ◽  
Cdte Qds ◽  
P450 Enzyme

A light-controlled drug metabolism system was successfully designed by using cytochrome P450 2C9 (CYP2C9) functionalized CdTe QDs as photocatalysts.

In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver

2007 ◽  
Vol 96 (2) ◽  
pp. 428-437 ◽  
Author(s):  
Miki Katoh ◽  
Toshiro Sawada ◽  
Yoshinori Soeno ◽  
Miki Nakajima ◽  
Chise Tateno ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Cytochrome P450 Enzyme ◽  
Chimeric Mice ◽  
Human Cytochrome ◽  
P450 Enzyme ◽  
Metabolism Model ◽  
In Vivo Drug Metabolism ◽  
Human Cytochrome P450 Enzyme

Association between the CYP2C9 polymorphism and the drug metabolism phenotype

2004 ◽  
Vol 42 (1) ◽  
Author(s):  
Elizabeta Topic ◽  
Mario Štefanovic ◽  
Marina Samardžija
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Cytochrome P450 Enzyme ◽  
Functional Polymorphism ◽  
Cyp2c9 Polymorphism ◽  
P450 Enzyme ◽  
Variant Alleles

AbstractCYP2C9, an isoform of the cytochrome P450 enzyme, is involved in the metabolism of most of the drugs of choice for the treatment of thromboembolic disorders. Functional polymorphism is associated with two variant alleles (alleles

Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500�m)

2005 ◽  
Vol 61 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Michael Streit ◽  
Christoph G�ggelmann ◽  
Christoph Dehnert ◽  
J�rgen Burhenne ◽  
Klaus-Dieter Riedel ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Acute Hypoxia ◽  
Cytochrome P450 Enzyme ◽  
P450 Enzyme

The role of cytochrome P450 enzyme genetic variants in cannabis hyperemesis syndrome—A case report

2021 ◽  
Author(s):  
Maxim Kuzin ◽  
Franziskos Xepapadakos ◽  
Isabel Scharrer ◽  
Marc Augsburger ◽  
Chin‐Bin Eap ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Case Report ◽  
Genetic Variants ◽  
Cytochrome P450 Enzyme ◽  
P450 Enzyme ◽  
Cannabis Hyperemesis Syndrome
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