Electrochemical Signal Amplification for Immunosensor Based on 3D Interdigitated Array Electrodes

2014 ◽  
Vol 86 (12) ◽  
pp. 5991-5998 ◽  
Author(s):  
Donghoon Han ◽  
Yang-Rae Kim ◽  
Chung Mu Kang ◽  
Taek Dong Chung
Keyword(s):  
Signal Amplification ◽  
Interdigitated Array Electrodes ◽  
Electrochemical Signal ◽  
Interdigitated Array

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

scholarly journals DNA/RNA Electrochemical Biosensing Devices a Future Replacement of PCR Methods for a Fast Epidemic Containment

Sensors ◽  
2020 ◽  
Vol 20 (16) ◽  
pp. 4648 ◽  
Author(s):  
Manikandan Santhanam ◽  
Itay Algov ◽  
Lital Alfonta
Keyword(s):  
Signal Amplification ◽  
Nucleic Acid Hybridization ◽  
Diagnostic Tools ◽  
Testing Method ◽  
Reverse Transcription Pcr ◽  
Electrochemical Biosensing ◽  
Low Copy Number ◽  
Rna Sensors ◽  
Electrochemical Signal ◽  
Sensitive Testing

Pandemics require a fast and immediate response to contain potential infectious carriers. In the recent 2020 Covid-19 worldwide pandemic, authorities all around the world have failed to identify potential carriers and contain it on time. Hence, a rapid and very sensitive testing method is required. Current diagnostic tools, reverse transcription PCR (RT-PCR) and real-time PCR (qPCR), have its pitfalls for quick pandemic containment such as the requirement for specialized professionals and instrumentation. Versatile electrochemical DNA/RNA sensors are a promising technological alternative for PCR based diagnosis. In an electrochemical DNA sensor, a nucleic acid hybridization event is converted into a quantifiable electrochemical signal. A critical challenge of electrochemical DNA sensors is sensitive detection of a low copy number of DNA/RNA in samples such as is the case for early onset of a disease. Signal amplification approaches are an important tool to overcome this sensitivity issue. In this review, the authors discuss the most recent signal amplification strategies employed in the electrochemical DNA/RNA diagnosis of pathogens.

scholarly journals In Vivo Two-Way Redox Cycling System for Independent Duplexed Electrochemical Signal Amplification

2019 ◽  
Vol 91 (8) ◽  
pp. 4939-4942 ◽  
Author(s):  
Yuan Yang ◽  
Yang-Yang Yu ◽  
Yu-Tong Shi ◽  
Jamile Mohammadi Moradian ◽  
Yang-Chun Yong
Keyword(s):  
Signal Amplification ◽  
Redox Cycling ◽  
Electrochemical Signal ◽  
Cycling System

Electroluminescence of Hybrid Self-Organised Fibres Incorporating CdTe Quantum Dots

2012 ◽  
Vol 65 (9) ◽  
pp. 1257 ◽  
Author(s):  
Masanori Ando ◽  
Chie Hosokawa ◽  
Ping Yang ◽  
Norio Murase
Keyword(s):  
Quantum Dots ◽  
Electric Field ◽  
Room Temperature ◽  
Low Voltage ◽  
The Self ◽  
Cdte Quantum Dots ◽  
Electroluminescent Devices ◽  
Interdigitated Array Electrodes ◽  
Low Threshold ◽  
Interdigitated Array

We demonstrated electroluminescence from hybrid 1D glass fibres incorporating CdTe quantum dots with a thin SiO2 overlayer which contains CdS-like clusters. The self-organised fibres, prepared by refluxing precursor nanowires, exhibited red electroluminescence on Au interdigitated array electrodes at room temperature. Although fluctuation with time was observed in the electroluminescence, relatively low threshold electric field (2.6 × 106 V m–1) suggests that the CdTe quantum dots-based hybrid fibres are expected to be applied to low voltage driven electroluminescent devices.

Patterning with particles using three-dimensional interdigitated array electrodes with negative dielectrophoresis and its application to simple immunosensing

2012 ◽  
Vol 82 ◽  
pp. 35-42 ◽  
Author(s):  
Masashi Yamamoto ◽  
Tomoyuki Yasukawa ◽  
Masato Suzuki ◽  
Satoshi Kosuge ◽  
Hitoshi Shiku ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Interdigitated Array Electrodes ◽  
Interdigitated Array
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