Reply to Comment on “Partition Coefficient Measurements in Picoliter Drops Using a Segmented Flow Microfluidic Device”

2013 ◽  
Vol 85 (21) ◽  
pp. 10623-10624
Author(s):  
Jonathan D. Posner ◽  
Nathan A. Marine
2009 ◽  
Vol 81 (4) ◽  
pp. 1471-1476 ◽  
Author(s):  
Nathan A. Marine ◽  
Steven A. Klein ◽  
Jonathan D. Posner

2013 ◽  
Vol 85 (21) ◽  
pp. 10620-10622 ◽  
Author(s):  
Zeqing Bai ◽  
Qiaohong He ◽  
Hengwu Chen ◽  
Min Wang

2008 ◽  
Vol 80 (21) ◽  
pp. 8231-8238 ◽  
Author(s):  
Gregory T. Roman ◽  
Meng Wang ◽  
Kristin N. Shultz ◽  
Colin Jennings ◽  
Robert T. Kennedy

The Analyst ◽  
2016 ◽  
Vol 141 (6) ◽  
pp. 1958-1965 ◽  
Author(s):  
Anumita Saha-Shah ◽  
Curtis M. Green ◽  
David H. Abraham ◽  
Lane A. Baker

We report development of a mobile and easy-to-fabricate theta pipette microfluidic device for segmented flow sampling.


1975 ◽  
Vol 14 (04) ◽  
pp. 301-309
Author(s):  
A. Marczak ◽  
A. Moszczyńska-Kowalska ◽  
H. Kowalski

SummaryThe relative solubility coefficient of 133Xe and the tissue-blood partition coefficient for the aqueous humour vitreous body, conjunctiva and external eye muscles of the rabbit were determined in vitro at 37° C and at various haematocrit values. The partition coefficient for haematocrit 40 was: for the aqueous humour 0,49 ml/ml, for the vitreous body 0,50 ml/ml, for the conjunctiva 0,81 ml/g and for the external eye muscles 0,77 ml/g. It was found that the solubility of 133Xe in rabbit erythrocytes is about 50 per cent higher than that in human red cells. The consequences of this fact for the precision of blood flow measurements by the method of tissue clearance are discussed.


1987 ◽  
Vol 26 (06) ◽  
pp. 253-257
Author(s):  
M. Mäntylä ◽  
J. Perkkiö ◽  
J. Heikkonen

The relative partition coefficients of krypton and xenon, and the regional blood flow in 27 superficial malignant tumour nodules in 22 patients with diagnosed tumours were measured using the 85mKr- and 133Xe-clearance method. In order to minimize the effect of biological variables on the measurements the radionuclides were injected simultaneously into the tumour. The distribution of the radiotracers was assumed to be in equilibrium at the beginning of the experiment. The blood perfusion was calculated by fitting a two-exponential function to the measuring points. The mean value of the perfusion rate calculated from the xenon results was 13 ± 10 ml/(100 g-min) [range 3 to 38 ml/(100 g-min)] and from the krypton results 19 ± 11 ml/(100 g-min) [range 5 to 45 ml/(100 g-min)]. These values were obtained, if the partition coefficients are equal to one. The equations obtained by using compartmental analysis were used for the calculation of the relative partition coefficient of krypton and xenon. The partition coefficient of krypton was found to be slightly smaller than that of xenon, which may be due to its smaller molecular weight.


2019 ◽  
Vol 139 (7) ◽  
pp. 209-216
Author(s):  
Jiaxu Wu ◽  
Yoshikazu Hirai ◽  
Ken-ichiro Kamei ◽  
Toshiyuki Tsuchiya ◽  
Osamu Tabata

2016 ◽  
Vol 136 (9) ◽  
pp. 384-389
Author(s):  
Kazuya Fujimoto ◽  
Hirofumi Shintaku ◽  
Hidetoshi Kotera ◽  
Ryuji Yokokawa

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