Nondenaturing Size-Exclusion Chromatography-Mass Spectrometry to Measure Stress-Induced Aggregation in a Complex Mixture of Monoclonal Antibodies

Jonathan Woodard; Hollis Lau; Ramil F. Latypov

doi:10.1021/ac401455f

Nondenaturing Size-Exclusion Chromatography-Mass Spectrometry to Measure Stress-Induced Aggregation in a Complex Mixture of Monoclonal Antibodies

Analytical Chemistry ◽

10.1021/ac401455f ◽

2013 ◽

Vol 85 (13) ◽

pp. 6429-6436 ◽

Cited By ~ 23

Author(s):

Jonathan Woodard ◽

Hollis Lau ◽

Ramil F. Latypov

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibodies ◽

Size Exclusion Chromatography ◽

Complex Mixture ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography ◽

Induced Aggregation

Download Full-text

Post-Column Denaturation-Assisted Native Size-Exclusion Chromatography–Mass Spectrometry for Rapid and In-Depth Characterization of High Molecular Weight Variants in Therapeutic Monoclonal Antibodies

Journal of the American Society for Mass Spectrometry ◽

10.1021/jasms.1c00289 ◽

2021 ◽

Author(s):

Yuetian Yan ◽

Tao Xing ◽

Anita P. Liu ◽

Zhengqi Zhang ◽

Shunhai Wang ◽

...

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Monoclonal Antibodies ◽

High Molecular Weight ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography ◽

Therapeutic Monoclonal Antibodies

Download Full-text

Size-exclusion chromatography-mass spectrometry with m-nitrobenzyl alcohol as post-column additive for direct characterization of size variants of monoclonal antibodies

Journal of Chromatography B ◽

10.1016/j.jchromb.2014.04.023 ◽

2014 ◽

Vol 960 ◽

pp. 230-238 ◽

Cited By ~ 8

Author(s):

Chong-Feng Xu ◽

Li Zang ◽

Andrew Weiskopf

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibodies ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Nitrobenzyl Alcohol ◽

Exclusion Chromatography

Download Full-text

Determination of fragrance allergens in cosmetics by size-exclusion chromatography followed by gas chromatography–mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2006.07.055 ◽

2006 ◽

Vol 1132 (1-2) ◽

pp. 109-116 ◽

Cited By ~ 29

Author(s):

M. Niederer ◽

R. Bollhalder ◽

Ch. Hohl.

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Gas Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography

Download Full-text

On-line size exclusion chromatography–pyrolysis-gas chromatography–mass spectrometry for copolymer characterization and additive analysis

Journal of Chromatography A ◽

10.1016/j.chroma.2006.12.054 ◽

2007 ◽

Vol 1143 (1-2) ◽

pp. 182-189 ◽

Cited By ~ 25

Author(s):

Erwin R. Kaal ◽

Geert Alkema ◽

Mitsuhiro Kurano ◽

Margit Geissler ◽

Hans-Gerd Janssen

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Gas Chromatography Mass Spectrometry ◽

Pyrolysis Gas ◽

Pyrolysis Gas Chromatography ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography ◽

On Line

Download Full-text

Untargeted Defining Protein–Metabolites Interaction Based on Label-Free Kinetic Size Exclusion Chromatography-Mass Spectrometry

Analytical Chemistry ◽

10.1021/acs.analchem.0c00495 ◽

2020 ◽

Vol 92 (11) ◽

pp. 7657-7665

Author(s):

Bohong Wang ◽

Wangjie Lv ◽

Mengmeng Chang ◽

Chunxia Zhao ◽

Xianzhe Shi ◽

...

Keyword(s):

Mass Spectrometry ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Label Free ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography

Download Full-text

On-line size-exclusion chromatography/mass spectrometry of low molecular mass heparin

Journal of Mass Spectrometry ◽

10.1002/jms.723 ◽

2004 ◽

Vol 39 (11) ◽

pp. 1305-1312 ◽

Cited By ~ 39

Author(s):

Jens Henriksen ◽

Lene Hoffmeyer Ringborg ◽

Peter Roepstorrf

Keyword(s):

Mass Spectrometry ◽

Molecular Mass ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography ◽

On Line

Download Full-text

Essential Oils Investigated by Size Exclusion Chromatography and Gas Chromatography−Mass Spectrometry

Energy & Fuels ◽

10.1021/ef050364i ◽

2006 ◽

Vol 20 (2) ◽

pp. 734-737 ◽

Cited By ~ 18

Author(s):

Trevor J. Morgan ◽

William E. Morden ◽

Eiman Al-muhareb ◽

Alan A. Herod ◽

Rafael Kandiyoti

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Essential Oils ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Gas Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography

Download Full-text

Drug screening of pharmaceutical discovery compounds by micro-size exclusion chromatography/mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.546 ◽

2001 ◽

Vol 16 (2) ◽

pp. 85-91 ◽

Cited By ~ 30

Author(s):

Paul A. Wabnitz ◽

Joseph A. Loo

Keyword(s):

Mass Spectrometry ◽

Size Exclusion Chromatography ◽

Drug Screening ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography

Download Full-text

Quantitative determination of wine polysaccharides by gas chromatography–mass spectrometry (GC–MS) and size exclusion chromatography (SEC)

Food Chemistry ◽

10.1016/j.foodchem.2011.08.049 ◽

2012 ◽

Vol 131 (1) ◽

pp. 367-374 ◽

Cited By ~ 46

Author(s):

Zenaida Guadalupe ◽

Olga Martínez-Pinilla ◽

Álvaro Garrido ◽

José David Carrillo ◽

Belén Ayestarán

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Quantitative Determination ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Gas Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography

Download Full-text

Size exclusion chromatography/mass spectrometry applied to the analysis of polysaccharides

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.458 ◽

2001 ◽

Vol 15 (23) ◽

pp. 2273-2283 ◽

Cited By ~ 39

Author(s):

Michael J. Deery ◽

Elaine Stimson ◽

Colin G. Chappell

Keyword(s):

Mass Spectrometry ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography

Download Full-text