Enhancement in the Sensitivity of Microfluidic Enzyme-Linked Immunosorbent Assays through Analyte Preconcentration

2012 ◽  
Vol 84 (16) ◽  
pp. 7029-7036 ◽  
Author(s):  
Naoki Yanagisawa ◽  
Debashis Dutta
2015 ◽  
Vol 22 (5) ◽  
pp. 432-442 ◽  
Author(s):  
Joao Silva ◽  
Flavia Calmon-Hamaty ◽  
Wilson Savino ◽  
Michael Hahne ◽  
Ernesto Caffarena

Author(s):  
Karin Lopatko Lindman ◽  
Bodil Weidung ◽  
Jan Olsson ◽  
Maria Josefsson ◽  
Anders Johansson ◽  
...  

Background: Amyloid-β (Aβ), the key constituent of Alzheimer’s disease (AD) plaques, has antimicrobial properties. Objective: To investigate the association between plasma Aβ and antibodies against the AD-related pathogens herpes simplex virus (HSV), cytomegalovirus (CMV), and C. pneumoniae. Methods: Plasma from 339 AD cases, obtained on average 9.4 years (±4.00) before diagnosis, and their matched controls were analyzed for Aβ40 and Aβ42 concentrations with Luminex xMAP technology and INNOBIA plasma Aβ-form assays. Enzyme-linked immunosorbent assays were utilized for analyses of anti-HSV immunoglobulin (Ig) G, anti-HSV1 IgG, anti-HSV2 IgG, anti-CMV IgG, and anti-C. pneumoniae IgG. Follow-up samples were available for 163 of the cases. Results: Presence and levels of anti-HSV1 IgG, anti-HSV2 IgG, anti-CMV IgG, and anti-C. pneumoniae IgG did not correlate with concentrations of Aβ42 or Aβ40 in cases or controls. Conclusion: Levels of plasma Aβ were not associated with antibodies against different AD-related Spathogens.


2008 ◽  
Vol 22 (4) ◽  
pp. 234-238 ◽  
Author(s):  
Harry E. Prince ◽  
Cindy Yeh ◽  
Navid Alem ◽  
Mandana Asalkhou ◽  
Nina Hamedi ◽  
...  

2010 ◽  
Vol 671 (1-2) ◽  
pp. 70-79 ◽  
Author(s):  
Eva M. Brun ◽  
Ana Torres ◽  
Rosa Ventura ◽  
Rosa Puchades ◽  
Ángel Maquieira

Sign in / Sign up

Export Citation Format

Share Document