DNA-Based Hybridization Chain Reaction for Amplified Bioelectronic Signal and Ultrasensitive Detection of Proteins

2012 ◽  
Vol 84 (12) ◽  
pp. 5392-5399 ◽  
Author(s):  
Bing Zhang ◽  
Bingqian Liu ◽  
Dianping Tang ◽  
Reinhard Niessner ◽  
Guonan Chen ◽  
...  
Keyword(s):  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction

Target triggered ultrasensitive electrochemical polychlorinated biphenyl aptasensor based on DNA microcapsules and nonlinear hybridization chain reaction

The Analyst ◽  
2020 ◽  
Vol 145 (10) ◽  
pp. 3598-3604 ◽  
Author(s):  
Ting Han ◽  
Shaozhen Wang ◽  
Feifan Sheng ◽  
Sicheng Wang ◽  
Tianyue Dai ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls ◽  
Polychlorinated Biphenyl ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction

In this work, we demonstrated an ultrasensitive detection platform for polychlorinated biphenyls (PCBs) based on DNA microcapsules and a nonlinear hybridization chain reaction (NHCR).

Versatile fluorescence detection of microRNA based on novel DNA hydrogel-amplified signal probes coupled with DNA walker amplification

2019 ◽  
Vol 55 (27) ◽  
pp. 3919-3922 ◽  
Author(s):  
Chunli Li ◽  
Hongkun Li ◽  
Junjun Ge ◽  
Guifen Jie
Keyword(s):  
Fluorescence Detection ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction ◽  
Dna Walker ◽  
Dna Hydrogel

A novel DNA hydrogel-amplified versatile fluorescence platform combined with hybridization chain reaction (HCR) and DNA walking multiple amplification was developed for ultrasensitive detection of miRNA.

Ultrasensitive detection of the androgen receptor through the recognition of an androgen receptor response element and hybridization chain amplification

The Analyst ◽  
2019 ◽  
Vol 144 (6) ◽  
pp. 2179-2185 ◽  
Author(s):  
Binbin Yao ◽  
Sha Zhu ◽  
Xinyu Xu ◽  
Ninghan Feng ◽  
Yaping Tian ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Restriction Endonuclease ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Dna Duplex ◽  
Chain Reaction ◽  
Response Element ◽  
Receptor Response

The androgen receptor is detected through the protection of a DNA duplex from restriction endonuclease-mediated digestion and a subsequent hybridization chain reaction.

MnO2 nanosheet-based heparin and OSCS fluorescent biosensor with lowered background and amplified hybridization chain reaction

RSC Advances ◽  
2016 ◽  
Vol 6 (92) ◽  
pp. 89803-89809 ◽  
Author(s):  
Ruifen Tian ◽  
Hong Jiang ◽  
Guangfeng Wang
Keyword(s):  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction ◽  
Fluorescent Biosensor ◽  
Turn On ◽  
Amplification Strategy ◽  
Mno2 Nanosheet

A “turn-on” ultrasensitive detection of heparin or OSCS was reported through MnO2 nanosheet quenched-ultralow background and HCR amplification strategy.

Phosphorylation-induced hybridization chain reaction on beads: an ultrasensitive flow cytometric assay for the detection of T4 polynucleotide kinase activity

2015 ◽  
Vol 51 (27) ◽  
pp. 5832-5835 ◽  
Author(s):  
Yuecheng Zhang ◽  
Chenghui Liu ◽  
Sujuan Sun ◽  
Yanli Tang ◽  
Zhengping Li
Keyword(s):  
Kinase Activity ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Flow Cytometric Assay ◽  
Chain Reaction ◽  
Flow Cytometric ◽  
Polynucleotide Kinase ◽  
T4 Polynucleotide Kinase

A versatile flow cytometric bead assay (FCBA) has been developed for an ultrasensitive detection of T4 PNK activity.

Dual amplification ratiometric biosensor based on a DNA tetrahedron nanostructure and hybridization chain reaction for the ultrasensitive detection of microRNA-133a

2019 ◽  
Vol 55 (77) ◽  
pp. 11551-11554 ◽  
Author(s):  
Liping Zhu ◽  
Jing Ye ◽  
Shuang Wang ◽  
Mengxia Yan ◽  
Qiuju Zhu ◽  
...  
Keyword(s):  
High Accuracy ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction ◽  
Dna Tetrahedron ◽  
Dual Amplification

A novel ratiometric electrochemiluminescence–electrochemical hybrid biosensor with high accuracy and reproducibility was fabricated for the ultrasensitive detection of miRNA-133a.

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