scholarly journals Reversible Cation Response with a Protein-Modified Nanopipette

2011 ◽  
Vol 83 (16) ◽  
pp. 6121-6126 ◽  
Author(s):  
Boaz Vilozny ◽  
Paolo Actis ◽  
R. Adam Seger ◽  
Queralt Vallmajo-Martin ◽  
Nader Pourmand
Keyword(s):  
2019 ◽  
Author(s):  
Isaac Omari ◽  
Parmissa Randhawa ◽  
Jaiya Randhawa ◽  
Jenny Yu ◽  
J Scott McIndoe

<p>The abundance of an ion in an electrospray ionization mass spectrum is dependent on many factors beyond just solution concentration. Even in cases where the ions are permanently charged and do not rely on protonation or other chemical processes to acquire the necessary charge, factors such as cation structure, molecular weight, solvent, and the identity of the anion can perturb results. Screening of a variety of combinations of cation, anion and solvent provided insight into some of the more important factors. Rigid cations and high conductivity anions tended to provide the highest responses, while acetonitrile was the most accurate solvent for reflecting solution composition. Functional groups that had affinity for the solvent tended to depress response. These observations will provide predictive power when accounting for ions that for reasons of high reactivity can not be isolated.</p><br>


Langmuir ◽  
1994 ◽  
Vol 10 (4) ◽  
pp. 991-993 ◽  
Author(s):  
Leonid Boguslavsky ◽  
Thomas W. Bell

2017 ◽  
Vol 12 (2) ◽  
pp. 252-261 ◽  
Author(s):  
Yaodong Huang ◽  
Shuxue Liu ◽  
Zhuofeng Xie ◽  
Zipei Sun ◽  
Wei Chai ◽  
...  

1999 ◽  
Vol 28 (1) ◽  
pp. 299-309 ◽  
Author(s):  
David R. DeWalle ◽  
Jeffrey S. Tepp ◽  
Bryan R. Swistock ◽  
William E. Sharpe ◽  
Pamela J. Edwards

2019 ◽  
Author(s):  
Isaac Omari ◽  
Parmissa Randhawa ◽  
Jaiya Randhawa ◽  
Jenny Yu ◽  
J Scott McIndoe

<p>The abundance of an ion in an electrospray ionization mass spectrum is dependent on many factors beyond just solution concentration. Even in cases where the ions are permanently charged and do not rely on protonation or other chemical processes to acquire the necessary charge, factors such as cation structure, molecular weight, solvent, and the identity of the anion can perturb results. Screening of a variety of combinations of cation, anion and solvent provided insight into some of the more important factors. Rigid cations and high conductivity anions tended to provide the highest responses, while acetonitrile was the most accurate solvent for reflecting solution composition. Functional groups that had affinity for the solvent tended to depress response. These observations will provide predictive power when accounting for ions that for reasons of high reactivity can not be isolated.</p><br>


1982 ◽  
Vol 60 (12) ◽  
pp. 1505-1513 ◽  
Author(s):  
James R. Oster ◽  
Guido O. Perez ◽  
Janet M. Canterbury ◽  
Helen C. Alpert ◽  
Carlos A. Vaamonde

Since the effect of acute administration of acid upon blood magnesium and parathyroid hormone (PTH) is unclear we infused anesthetized dogs with saline (controls), HCl, lactic, and methylmalonic acids for 3 h. In all groups but lactic acid, plasma magnesium decreased; ionized calcium levels were increased by all three acids. Nevertheless, PTH increased in each of six dogs following methylmalonic acid and decreased in four of six animals after lactic acid. The decrease in plasma magnesium concentration after methylmalonic acid appeared to be an important factor in explaining the disparate PTH changes in these two groups because concomitant magnesium administration obviated the increases in PTH in four of six additional methylmalonic acid-infused dogs.


2019 ◽  
Vol 30 (9) ◽  
pp. 1750-1757 ◽  
Author(s):  
Isaac Omari ◽  
Parmissa Randhawa ◽  
Jaiya Randhawa ◽  
Jenny Yu ◽  
J. Scott McIndoe

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