Continuous Flow Microfluidic Demixing of Electrolytes by Induced Charge Electrokinetics in Structured Electrode Arrays

2006 ◽  
Vol 78 (5) ◽  
pp. 1425-1434 ◽  
Author(s):  
Felix C. Leinweber ◽  
Jan C. T. Eijkel ◽  
Johan G. Bomer ◽  
Albert van den Berg
Soft Matter ◽  
2018 ◽  
Vol 14 (6) ◽  
pp. 1056-1066 ◽  
Author(s):  
Cunlu Zhao ◽  
Chun Yang

In this work, we report an effective microfluidic technique for continuous-flow trapping and localized enrichment of micro- and nano-particles by using induced-charge electrokinetic (ICEK) phenomena.


RSC Advances ◽  
2015 ◽  
Vol 5 (82) ◽  
pp. 66602-66610 ◽  
Author(s):  
Yankai Jia ◽  
Yukun Ren ◽  
Hongyuan Jiang

Efficient continuous-flow focusing of microparticles using induced-charge electroosmosis is presented and 3D AgPDMS electrodes are employed to avoid the negative effects of alternating current electroosmosis and dielectrophoresis.


Lab on a Chip ◽  
2016 ◽  
Vol 16 (15) ◽  
pp. 2803-2812 ◽  
Author(s):  
Yukun Ren ◽  
Jiangwei Liu ◽  
Weiyu Liu ◽  
Qi Lang ◽  
Ye Tao ◽  
...  

We propose a novel continuous-flow microfluidic particle concentrator with a specified focusing-particle number ratio (FR) at different channel outlets using induced-charge electroosmosis (ICEO).


Micromachines ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 447 ◽  
Author(s):  
Kai Du ◽  
Jingni Song ◽  
Weiyu Liu ◽  
Ye Tao ◽  
Yukun Ren

We present herein a unique concept of multifrequency induced-charge electroosmosis (MICEO) actuated directly on driving electrode arrays, for highly-efficient simultaneous transport and convective mixing of fluidic samples in microscale ducts. MICEO delicately combines transversal AC electroosmotic vortex flow, and axial traveling-wave electroosmotic pump motion under external dual-Fourier-mode AC electric fields. The synthetic flow field associated with MICEO is mathematically analyzed under thin layer limit, and the particle tracing experiment with a special powering technique validates the effectiveness of this physical phenomenon. Meanwhile, the simulation results with a full-scale 3D computation model demonstrate its robust dual-functionality in inducing fully-automated analyte transport and chaotic stirring in a straight fluidic channel embedding double-sided quarter-phase discrete electrode arrays. Our physical demonstration with multifrequency signal control on nonlinear electroosmosis provides invaluable references for innovative designs of multifunctional on-chip analytical platforms in modern microfluidic systems.


Nanoscale ◽  
2019 ◽  
Vol 11 (13) ◽  
pp. 6410-6421 ◽  
Author(s):  
Xiaoming Chen ◽  
Yukun Ren ◽  
Likai Hou ◽  
Xiangsong Feng ◽  
Tianyi Jiang ◽  
...  

We present a direct particle separation method based on induced charge electro-osmotic vortices in continuous flow.


Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 727
Author(s):  
Mafalda Ribeiro ◽  
Pamela Ali ◽  
Benjamin Metcalfe ◽  
Despina Moschou ◽  
Paulo R. F. Rocha

Organ-on-Chip technology is commonly used as a tool to replace animal testing in drug development. Cells or tissues are cultured on a microchip to replicate organ-level functions, where measurements of the electrical activity can be taken to understand how the cell populations react to different drugs. Microfluidic structures are integrated in these devices to replicate more closely an in vivo microenvironment. Research has provided proof of principle that more accurate replications of the microenvironment result in better micro-physiological behaviour, which in turn results in a higher predictive power. This work shows a transition from a no-flow (static) multi-electrode array (MEA) to a continuous-flow (dynamic) MEA, assuring a continuous and homogeneous transfer of an electrolyte solution across the measurement chamber. The process through which the microfluidic system was designed, simulated, and fabricated is described, and electrical characterisation of the whole structure under static solution and a continuous flow rate of 80 µL/min was performed. The latter reveals minimal background disturbance, with a background noise below 30 µVpp for all flow rates and areas. This microfluidic MEA, therefore, opens new avenues for more accurate and long-term recordings in Organ-on-Chip systems.


2020 ◽  
Vol 22 (19) ◽  
pp. 6437-6443
Author(s):  
Cheng-Kou Liu ◽  
Meng-Yi Chen ◽  
Xin-Xin Lin ◽  
Zheng Fang ◽  
Kai Guo

A catalyst-, oxidant-, acidic solvent- and quaternary ammonium salt-free electrochemical para-selective hydroxylation of N-arylamides at rt in batch and continuous-flow was developed.


2021 ◽  
Vol 147 (3) ◽  
pp. 04021002
Author(s):  
Wenrui Qu ◽  
Shaojie Liu ◽  
Qun Zhao ◽  
Yi Qi

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