Rectilinear Ion Trap Mass Spectrometer with Atmospheric Pressure Interface and Electrospray Ionization Source

2006 ◽  
Vol 78 (3) ◽  
pp. 718-725 ◽  
Author(s):  
Qingyu Song ◽  
Sameer Kothari ◽  
Michael A. Senko ◽  
Jae C. Schwartz ◽  
Jonathan W. Amy ◽  
...  
Keyword(s):  
Electrospray Ionization ◽  
Mass Spectrometer ◽  
Atmospheric Pressure ◽  
Ion Trap ◽  
Ionization Source ◽  
Ion Trap Mass Spectrometer

scholarly journals High-Throughput LC/MS/MS Analysis of Ruscogenin and Neoruscogenin in Ruscus aculeatus L.

2009 ◽  
Vol 92 (4) ◽  
pp. 1055-1059 ◽  
Author(s):  
Laurian Vlase ◽  
Béla Kiss ◽  
Georgeta Balica ◽  
Mircea Tas ◽  
Gianina Crisan ◽  
...  
Keyword(s):  
Electrospray Ionization ◽  
Mass Spectrometer ◽  
High Throughput ◽  
Ion Trap ◽  
Multiple Reaction Monitoring ◽  
Reaction Monitoring ◽  
Ionization Source ◽  
Ion Trap Mass Spectrometer ◽  
Multiple Reaction Monitoring Mode ◽  
Ionization Mode

Abstract A new, sensitive LC/MS/MS method was developed for the quantification of ruscogenin and neoruscogenin in hydrolyzed extracts from Ruscus aculeatus L. (Liliaceae). The two sapogenins were separated on a Zorbax SB-C18 column under isocratic conditions. The detection was performed in the multiple reaction monitoring mode using an ion trap mass spectrometer with an electrospray ionization source operated in positive ionization mode. For the quantification of the ruscogenin and neoruscogenin, calibration curves were constructed over the range of 21000 ng/mL. This is the first reported LC/MS/MS method for the simultaneous analysis of ruscogenin and neoruscogenin, and it showed superior sensitivity when compared with other assays described in the literature. The method has been successfully applied to quantify the two sapogenins in aerial (phylloclades) and underground parts (rhizomes, roots) of Ruscus aculeatus L.

Development and Characterization of a Field-Deployable Ion-Trap Mass Spectrometer with an Atmospheric Pressure Interface

2012 ◽  
Vol 84 (22) ◽  
pp. 10105-10112 ◽  
Author(s):  
Alexander Misharin ◽  
Konstantin Novoselov ◽  
Victor Laiko ◽  
Vladimir M. Doroshenko
Keyword(s):  
Mass Spectrometer ◽  
Atmospheric Pressure ◽  
Ion Trap ◽  
Ion Trap Mass Spectrometer
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