Macro-/Nanoporous Silicon as a Support for High-Performance Protein Microarrays

2003 ◽  
Vol 75 (24) ◽  
pp. 6968-6974 ◽  
Author(s):  
Anton Ressine ◽  
Simon Ekström ◽  
György Marko-Varga ◽  
Thomas Laurell
Keyword(s):  
High Performance ◽  
Protein Microarrays ◽  
Nanoporous Silicon

From High Performance Protein Micro Chip Toward Ultra High Sensitive Single Molecule Nano Array

2009 ◽  
Author(s):  
Fan-Gang Tseng
Keyword(s):  
Single Molecule ◽  
High Performance ◽  
Dynamic Range ◽  
Early Stage ◽  
High Dynamic Range ◽  
Disease Diagnosis ◽  
Protein Microarrays ◽  
Detection Sensitivity ◽  
High Throughput Analysis ◽  
High Efficient

Protein microarrays have been employed to screen tens to thousands of proteins simultaneously for the observation of the biochemical activities in the protein-protein, protein-nucleic acid and small molecule interactions. This technology allows high throughput analysis and holds great potential for basic molecular biology research, disease marker identification, toxicological response profiling and pharmaceutical target screening. However, proteins easily malfunction in harsh environments so that they are hardly preserved before the application because of their complex and fragile structures. On the other hand, identify scarce amount of proteins less than fM range is very important and challenge for disease diagnosis at very early stage. As a result, the procedures for protein micro array formation are very important for preserving protein functionality to ensure useful protein assays, as well as the improvement of the detection sensitivity up to single molecule event but with high dynamic range for disease early detection. Therefore, this paper provides a novel view from the preparation of high efficient protein micro chip toward ultra high sensitive single protein nano array through the technology integration of BioMEMS and Bio-Nanotechnology.

Zeptosens' protein microarrays: A novel high performance microarray platform for low abundance protein analysis

PROTEOMICS ◽  
2002 ◽  
Vol 2 (4) ◽  
pp. 383 ◽  
Author(s):  
Michael Pawlak ◽  
Eginhard Schick ◽  
Martin A. Bopp ◽  
Michael J. Schneider ◽  
Peter Oroszlan ◽  
...  
Keyword(s):  
High Performance ◽  
Protein Analysis ◽  
Microarray Platform ◽  
Protein Microarrays

High performance nanoporous silicon photoelectrodes co-catalyzed with an earth abundant [Mo3S13]2− nanocluster via drop coating

RSC Advances ◽  
2016 ◽  
Vol 6 (19) ◽  
pp. 15610-15614 ◽  
Author(s):  
Miao Kan ◽  
Jinping Jia ◽  
Yixin Zhao
Keyword(s):  
High Performance ◽  
Hydrogen Generation ◽  
Nanoporous Silicon ◽  
Earth Abundant

Earth abundant [Mo3S13]2− nanoclusters efficiently enhance a nanoporous silicon photoelectrode for hydrogen generation.

Randomly Oriented ZnO Nanorods As Advanced Substrate for High-Performance Protein Microarrays

2010 ◽  
Vol 2 (6) ◽  
pp. 1569-1572 ◽  
Author(s):  
Weihua Hu ◽  
Yingshuai Liu ◽  
Zhihong Zhu ◽  
Hongbin Yang ◽  
Chang Ming Li
Keyword(s):  
High Performance ◽  
Zno Nanorods ◽  
Protein Microarrays

scholarly journals High-performance nanoporous silicon-based photodetectors

Optik ◽  
2018 ◽  
Vol 168 ◽  
pp. 424-431 ◽  
Author(s):  
Asad A. Thahe ◽  
Hazri Bakhtiar ◽  
Noriah Bidin ◽  
Z. Hassan ◽  
M.A. Qaeed ◽  
...  
Keyword(s):  
High Performance ◽  
Nanoporous Silicon ◽  
Silicon Based

Structure-Controllable Binary Nanoporous-Silicon/Antimony Alloy as Anode for High-Performance Lithium-Ion Batteries

2018 ◽  
Vol 5 (23) ◽  
pp. 3809-3816 ◽  
Author(s):  
Chao Yuan ◽  
Shuai Liu ◽  
Yinghui Yang ◽  
Mengchun Yu ◽  
Yuan Tian ◽  
...  
Keyword(s):  
Lithium Ion Batteries ◽  
High Performance ◽  
Lithium Ion ◽  
Nanoporous Silicon ◽  
Antimony Alloy

A High Performance Energy Analyzer for Use in Electron Scanning Microscopy

1969 ◽  
Vol 27 ◽  
pp. 14-15
Author(s):  
A. V. Crewe ◽  
M. Isaacson ◽  
D. Johnson
Keyword(s):  
High Performance ◽  
Vertical Plane ◽  
Median Plane ◽  
Electron Gun ◽  
Uniform Field ◽  
Loss Mechanism ◽  
Electron Scanning Microscopy ◽  
Sector Type ◽  
Double Focusing ◽  
Electron Energy Loss

A double focusing magnetic spectrometer has been constructed for use with a field emission electron gun scanning microscope in order to study the electron energy loss mechanism in thin specimens. It is of the uniform field sector type with curved pole pieces. The shape of the pole pieces is determined by requiring that all particles be focused to a point at the image slit (point 1). The resultant shape gives perfect focusing in the median plane (Fig. 1) and first order focusing in the vertical plane (Fig. 2).

Vacuum System to Minimize the Specimen Contamination of High-Performance EM

1977 ◽  
Vol 35 ◽  
pp. 68-69
Author(s):  
N. Yoshimura ◽  
K. Shirota ◽  
T. Etoh
Keyword(s):  
Electron Microscope ◽  
High Speed ◽  
High Performance ◽  
High Vacuum ◽  
Vacuum System ◽  
Pump System ◽  
Pumping System ◽  
Diffusion Pump ◽  
Almost All ◽  
Cascade Type

One of the most important requirements for a high-performance EM, especially an analytical EM using a fine beam probe, is to prevent specimen contamination by providing a clean high vacuum in the vicinity of the specimen. However, in almost all commercial EMs, the pressure in the vicinity of the specimen under observation is usually more than ten times higher than the pressure measured at the punping line. The EM column inevitably requires the use of greased Viton O-rings for fine movement, and specimens and films need to be exchanged frequently and several attachments may also be exchanged. For these reasons, a high speed pumping system, as well as a clean vacuum system, is now required. A newly developed electron microscope, the JEM-100CX features clean high vacuum in the vicinity of the specimen, realized by the use of a CASCADE type diffusion pump system which has been essentially improved over its predeces- sorD employed on the JEM-100C.

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