Optimization of Particle Dimensions for High Efficiency in Capillary Electrochromatography

2003 ◽  
Vol 75 (19) ◽  
pp. 5246-5253 ◽  
Author(s):  
Remco Stol ◽  
Hans Poppe ◽  
Wim Th. Kok
Keyword(s):  
Capillary Electrochromatography ◽  
High Efficiency

scholarly journals Development of a Mobile Analytical Chemistry Workstation Using a Silicon Electrochromatography Microchip and Capacitively Coupled Contactless Conductivity Detector

Micromachines ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 239
Author(s):  
Yineng Wang ◽  
Xi Cao ◽  
Walter Messina ◽  
Anna Hogan ◽  
Justina Ugwah ◽  
...  
Keyword(s):  
Capillary Electrochromatography ◽  
High Efficiency ◽  
Device Fabrication ◽  
Capacitively Coupled ◽  
Packaging Design ◽  
Design And Optimization ◽  
Nanofabrication Technique ◽  
On Chip ◽  
Silicon Based ◽  
Rapid Separations

Capillary electrochromatography (CEC) is a separation technique that hybridizes liquid chromatography (LC) and capillary electrophoresis (CE). The selectivity offered by LC stationary phase results in rapid separations, high efficiency, high selectivity, minimal analyte and buffer consumption. Chip-based CE and CEC separation techniques are also gaining interest, as the microchip can provide precise on-chip control over the experiment. Capacitively coupled contactless conductivity detection (C4D) offers the contactless electrode configuration, and thus is not in contact with the solutions under investigation. This prevents contamination, so it can be easy to use as well as maintain. This study investigated a chip-based CE/CEC with C4D technique, including silicon-based microfluidic device fabrication processes with packaging, design and optimization. It also examined the compatibility of the silicon-based CEC microchip interfaced with C4D. In this paper, the authors demonstrated a nanofabrication technique for a novel microchip electrochromatography (MEC) device, whose capability is to be used as a mobile analytical equipment. This research investigated using samples of potassium ions, sodium ions and aspirin (acetylsalicylic acid).

Advances in Capillary Electrochromatography:  Rapid and High-Efficiency Separations of PAHs

1998 ◽  
Vol 70 (22) ◽  
pp. 4787-4792 ◽  
Author(s):  
Rajeev Dadoo ◽  
Richard N. Zare ◽  
Chao Yan ◽  
Deon S. Anex
Keyword(s):  
Capillary Electrochromatography ◽  
High Efficiency ◽  
High Efficiency Separations

scholarly journals Capillary Electrochromatography: A Powerful Tool for the Resolution of Complex Mixtures

1999 ◽  
Vol 82 (6) ◽  
pp. 1604-1612
Author(s):  
Patrick T Vallano ◽  
Vincent T Remcho
Keyword(s):  
Capillary Electrochromatography ◽  
Mobile Phase ◽  
High Efficiency ◽  
Capillary Liquid Chromatography ◽  
Complex Mixtures ◽  
Resolving Power ◽  
Separation Mechanism ◽  
Electrophoretic Separations ◽  
Capillary Electrophoretic ◽  
Capillary Liquid

Abstract Methods such as capillary electrophoresis (CE) and capillary liquid chromatography (LC) are particularly useful in the analysis of complex mixtures because of their high resolving power. Continued refinement of these techniques has led to a novel separation method known as capillary electrochromatography (CEC), also referred to as capillary electrokinetic chromatography, which is a combination of capillary LC and conventional CE. As in LC, mobile phase is transported through a column where partitioning of solutes occurs. In CEC, mobile phase flow is generated by electroosmosis, which arises when an electric potential is applied across the long axis of the capillary column. The favorable flow dynamics of electroosmosis result in higher chromatographic efficiencies in CEC relative to LC. If the species of interest are charged, a second separation mechanism is afforded by electrophoresis. CEC combines the high efficiency of capillary electrophoretic separations with the broad range of selectivity obtainable in LC. As such, CEC provides numerous advantages over other separation methods. This study introduces the theory, principles, instrumentation, and applications of this technique.

Pseudo-electrokinetic packing of high efficiency columns for capillary electrochromatography

2000 ◽  
Vol 873 (2) ◽  
pp. 293-298 ◽  
Author(s):  
R. Stol ◽  
M. Mazereeuw ◽  
U.R. Tjaden ◽  
J. van der Greef
Keyword(s):  
Capillary Electrochromatography ◽  
High Efficiency

High-Efficiency On-Line Concentration Technique of Capillary Electrochromatography

2000 ◽  
Vol 72 (22) ◽  
pp. 5744-5747 ◽  
Author(s):  
Yukui Zhang ◽  
Jun Zhu ◽  
Lihua Zhang ◽  
Weibing Zhang
Keyword(s):  
Capillary Electrochromatography ◽  
High Efficiency ◽  
Concentration Technique ◽  
On Line
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