Probing Antigen−Antibody Binding Processes by Impedance Measurements on Ion-Sensitive Field-Effect Transistor Devices and Complementary Surface Plasmon Resonance Analyses:  Development of Cholera Toxin Sensors

2002 ◽  
Vol 74 (18) ◽  
pp. 4763-4773 ◽  
Author(s):  
Maya Zayats ◽  
Oleg A. Raitman ◽  
Vladimir I. Chegel ◽  
Andrei B. Kharitonov ◽  
Itamar Willner
Keyword(s):  
Surface Plasmon Resonance ◽  
Cholera Toxin ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Antibody Binding ◽  
Impedance Measurements ◽  
Effect Transistor ◽  
Antigen Antibody

scholarly journals Dual Monitoring of Surface Reactions in Real Time by Combined Surface-Plasmon Resonance and Field-Effect Transistor Interrogation

2020 ◽  
Vol 142 (27) ◽  
pp. 11709-11716 ◽  
Author(s):  
Patrik Aspermair ◽  
Ulrich Ramach ◽  
Ciril Reiner-Rozman ◽  
Stefan Fossati ◽  
Bernadette Lechner ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Real Time ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Surface Reactions ◽  
Effect Transistor

scholarly journals EGFET-Based Sensors for Bioanalytical Applications: A Review

Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 4042 ◽  
Author(s):  
Salvatore Pullano ◽  
Costantino Critello ◽  
Ifana Mahbub ◽  
Nishat Tasneem ◽  
Samira Shamsir ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Low Cost ◽  
High Sensitivity ◽  
Nucleic Acid Hybridization ◽  
Protein Protein Interaction ◽  
Effect Transistor ◽  
Bioanalytical Applications ◽  
Antigen Antibody ◽  
Low Cost Manufacturing

Since the 1970s, a great deal of attention has been paid to the development of semiconductor-based biosensors because of the numerous advantages they offer, including high sensitivity, faster response time, miniaturization, and low-cost manufacturing for quick biospecific analysis with reusable features. Commercial biosensors have become highly desirable in the fields of medicine, food, and environmental monitoring as well as military applications, whereas increasing concerns about food safety and health issues have resulted in the introduction of novel legislative standards for these sensors. Numerous devices have been developed for monitoring biological processes such as nucleic acid hybridization, protein–protein interaction, antigen–antibody bonds, and substrate–enzyme reactions, just to name a few. Since the 1980s, scientific interest moved to the development of semiconductor-based devices, which also include integrated front-end electronics, such as the extended-gate field-effect transistor (EGFET) biosensor, one of the first miniaturized chemical sensors. This work is intended to be a review of the state of the art focused on the development of biosensors and chemosensors based on extended-gate field-effect transistor within the field of bioanalytical applications, which will highlight the most recent research reported in the literature. Moreover, a comparison among the diverse EGFET devices will be presented, giving particular attention to the materials and technologies.

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