Accelerated Solvent Extraction Followed by On-Line Solid-Phase Extraction Coupled to Ion Trap LC/MS/MS for Analysis of Benzalkonium Chlorides in Sediment Samples

2002 ◽  
Vol 74 (6) ◽  
pp. 1275-1280 ◽  
Author(s):  
Imma Ferrer ◽  
Edward T. Furlong
Keyword(s):  
Solvent Extraction ◽  
Solid Phase Extraction ◽  
Ion Trap ◽  
Solid Phase ◽  
Accelerated Solvent Extraction ◽  
Phase Extraction ◽  
Sediment Samples ◽  
On Line

On-line Solid-Phase Extraction Coupled to Liquid Chromatography–Ion Trap Tandem Mass Spectrometry for Determination of Penicillins in Catfish

2011 ◽  
Vol 5 (5) ◽  
pp. 1047-1053 ◽  
Author(s):  
Luana Maggi ◽  
Jorge Hurtado de Mendoza ◽  
Amaya Zalacain ◽  
Liliana Bonetto ◽  
Francisco A. Mocholí ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Solid Phase Extraction ◽  
Ion Trap ◽  
Solid Phase ◽  
Tandem Mass ◽  
Phase Extraction ◽  
On Line

scholarly journals Determination of Capsaicin and Dihydrocapsaicin in Some Chilli Varieties using Accelerated Solvent Extraction Associated with Solid-Phase Extraction Methods and RP-HPLC-Fluorescence

2012 ◽  
Vol 9 (3) ◽  
pp. 1550-1561 ◽  
Author(s):  
Saksit Chanthai ◽  
Jureerat Juangsamoot ◽  
Chalerm Ruangviriyachai ◽  
Suchila Techawongstien
Keyword(s):  
Solvent Extraction ◽  
Solid Phase Extraction ◽  
Limit Of Detection ◽  
Solid Phase ◽  
Accelerated Solvent Extraction ◽  
Phase Extraction ◽  
Good Precision ◽  
Real Samples ◽  
Relative Standard

Reversed phase-HPLC with fluorescence detection of two major capsaicinoids was described. Isocratic elution using a ratio of methanol and deionized water (66:34, v/v) as mobile phase was used at a flow rate of 0.9 mL/min with well achieved separation within 6 min. Under optimum conditions, their analytical figures of merit for the HPLC method were validated. The linearity was in the range of 1.0-25.0 μg/mL with multiple determination coefficients of higher than 0.995. The limit of detection was ranged of 0.008-0.01 μg/mL. The repeatability and reproducibility of the retention time and peak area for these compounds were in good precision with their relative standard deviations (RSDs) lower than 1% and 5%, respectively. Both capsaicin and dihydrocapsaicin were extracted using an accelerated solvent extraction (ASE) of methanol as an extraction solvent for 5 min static time with 3 cycles. The methanolic extracts were subjected to clean up with C18solid-phase extraction (SPE) with its recoveries ranking of 90.2-98.0%. The method recoveries of real samples were found to be 60.7-98.6%. The optimized extraction method were applied for the determination of the two capsaicinoids in ten vareities of hot chilli pepper samples. Total contents of capsaicinoids were found in the range of 2,307.0-9047.3 μg/g DW with their corresponding Scoville heat unit (SHU) of 34,600-135,700. Additionally, the contents of capsaicinoids using external calibration method comparing with those of standard addition were not significantly different, indicating accuracy of the method. Mostly, the contents of capsaicin found in these real samples were rather higher than those of dihydrocapsaicin.

scholarly journals Determination of Organophosphorus Esters in Fall Protection Equipment by Accelerated Solvent Extraction and Solid-Phase Extraction Coupled with LC-MS/MS Detection

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Haihong Li ◽  
Mingli Ye ◽  
Fangfang Wu ◽  
Xuyang Zhao ◽  
Lifeng Wang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Solvent Extraction ◽  
Solid Phase Extraction ◽  
Solid Phase ◽  
Accelerated Solvent Extraction ◽  
Phase Extraction ◽  
Water Mixture ◽  
Potential Health ◽  
Relative Standard ◽  
Fall Protection

An analysis method was established to determine 14 organophosphorus ester (OPE) flame retardants in fall protection equipment by combining accelerated solvent extraction (ASE) and solid-phase extraction (SPE) with high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The ASE parameters were optimized as follows: static extraction with acetonitrile at 80°C for 5 min for two cycles. The combined extract was purified with the ENVI-18 cartridge before further analysis. A HILIC column was used to separate the OPEs using an acetonitrile/water mixture as the mobile phase with the detection by the electrospray ionization mass spectrometry, which was operated under the positive mode. Under optimized conditions, the limit of detection for the target OPEs ranged in 0.015–1.33 ng/g, with a spike recovery of 71.6%–114% and a relative standard deviation of 0.8%–11.2%. The developed method was used to analyze OPEs in fall protection equipment (safety helmets and ropes), where OPEs were all detectable. Safety ropes displayed a higher concentration of OPEs than ones in safety helmets, with the pollutants being mainly triphenyl phosphate, 2-ethylhexyl diphenyl phosphate (EHDPP), tri(2-ethylhexyl) phosphate, and tri-n-butyl phosphate in the range of 11.07 ng/g‒815.53 ng/g. The EHDPP was the dominant compound in safety helmets with the concentration from 26.84 to 95.29 ng/g, while the other OPEs in safety helmets were lower than 5.136 ng/g. The potential health and environmental risks of these fall protection equipment during their use and disposal call for further attention.

Sign in / Sign up

Export Citation Format

Share Document