Nonaqueous reversed-phase liquid chromatographic fractionation of polystyrene

1982 ◽  
Vol 54 (4) ◽  
pp. 706-708 ◽  
Author(s):  
Daniel W. Armstrong ◽  
K. H. Bui
Keyword(s):  
Reversed Phase ◽  
Chromatographic Fractionation ◽  
Phase Liquid ◽  
Liquid Chromatographic

scholarly journals Application of Liquid Chromatography to the Simultaneous Determination of Acetylsalicylic Acid, Caffeine, Codeine, Paracetamol, Pyridoxine, and Thiamine in Pharmaceutical Preparations

2001 ◽  
Vol 84 (3) ◽  
pp. 676-683 ◽  
Author(s):  
Natividad Ramos-Martos ◽  
Francisco Aguirre-Gómez ◽  
Antonio Molina-Díaz ◽  
Luis F Capitán-Vallvey
Keyword(s):  
Salicylic Acid ◽  
Acetylsalicylic Acid ◽  
Simultaneous Determination ◽  
Pharmaceutical Preparations ◽  
Reversed Phase ◽  
Liquid Chromatographic Method ◽  
Relative Standard ◽  
Phase Liquid ◽  
Liquid Chromatographic

Abstract This paper describes a rapid reversed-phase liquid chromatographic method, with UV detection, for the simultaneous determination of acetylsalicylic acid, caffeine, codeine, paracetamol, pyridoxine, and thiamine in pharmaceutical preparations. A reversed-phase C18 Nucleosil column is used. The mobile phase consists of 2 successive eluants: water (5 min) and acetonitrile–water (75 + 25, v/v; 9 min), both adjusted to pH 2.1 with phosphoric acid. Before determination acetylsalicylic acid is completely converted to salicylic acid by alkaline hydrolysis. Salicylic acid, caffeine, paracetamol, pyridoxine, and thiamine are all detected at 285 nm, whereas codeine is detected at 240 nm. Calibration curves were linear for salicylic acid, caffeine, paracetamol, and pyridoxine in the range of 50–500 mg/L, and for codeine and thiamine in the range of 50–1000 mg/L. The method was applied to the analysis of 13 fortified commercial pharmaceutical preparations. Recoveries ranged from 92.6 to 105.5%, with relative standard deviations of 1.1–5.8%.

Separation of Proteic Primary Amino Acids under Several Reversed‐Phase Liquid Chromatographic Conditions

2006 ◽  
Vol 29 (17) ◽  
pp. 2521-2536 ◽  
Author(s):  
V. Concha‐Herrera ◽  
J. R. Torres‐Lapasió ◽  
G. Vivó‐Truyols ◽  
M. C. García‐Álvarez‐Coque
Keyword(s):  
Amino Acids ◽  
Reversed Phase ◽  
Primary Amino ◽  
Phase Liquid ◽  
Liquid Chromatographic
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