Effect of Solution Ionic Strength on Analyte Charge State Distributions in Positive and Negative Ion Electrospray Mass Spectrometry

1994 ◽  
Vol 66 (21) ◽  
pp. 3702-3708 ◽  
Author(s):  
Guangdi. Wang ◽  
Richard B. Cole
Keyword(s):  
Mass Spectrometry ◽  
Ionic Strength ◽  
Charge State ◽  
Electrospray Mass Spectrometry ◽  
Negative Ion ◽  
Solution Ionic Strength ◽  
Charge State Distributions

Determination of Solution Ions by Electrospray Mass Spectrometry

1994 ◽  
Vol 48 (6) ◽  
pp. 655-661 ◽  
Author(s):  
George R. Agnes ◽  
Gary Horlick
Keyword(s):  
Mass Spectrometry ◽  
Metal Ion ◽  
Gas Flow ◽  
Electrospray Mass Spectrometry ◽  
Negative Ion ◽  
Molecular Forms ◽  
Mass Spectral ◽  
Oxo Anions ◽  
Electrospray Source

Spectral results are presented illustrating the capability of electrospray mass spectrometry (ES-MS) for the determination of the composition of solution samples. The solution components that can be determined include the elemental and molecular forms of anions and cations. Three modes of positive-ion ES-MS are described: the ion cluster mode, the metal-ion mode, and an intermediate mode. The modes are established by operating the electrospray source at specific voltages and curtain gas flow rate values, and each mode provides a unique mass spectral picture of the solution components with primary focus on cationic species (i.e., metal ions). Results are also presented for operation of the electrospray source in negative-ion mode. In this mode both elemental anions (i.e., halides) and molecular anions (i.e., oxo-anions) can be determined.

Increasing Protein Charge State When Using Laser Electrospray Mass Spectrometry

2015 ◽  
Vol 26 (5) ◽  
pp. 706-715 ◽  
Author(s):  
Santosh Karki ◽  
Paul M. Flanigan ◽  
Johnny J. Perez ◽  
Jieutonne J. Archer ◽  
Robert J. Levis
Keyword(s):  
Mass Spectrometry ◽  
Charge State ◽  
Electrospray Mass Spectrometry ◽  
Protein Charge
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