High-frequency impedance analysis of quartz crystal microbalances. 1. General considerations

1994 ◽  
Vol 66 (4) ◽  
pp. 484-491 ◽  
Author(s):  
Marc A. M. Noel ◽  
Patrice A. Topart
DYNA ◽  
2020 ◽  
Vol 87 (212) ◽  
pp. 163-168
Author(s):  
Camilo Ortiz Monsalve ◽  
Jorge Mario Guerra González ◽  
Marisol Jaramillo Grajales

In recent years, researchers have taken to biosensors as effective tools for detection due to their portability, low-cost, fast response, and practicality. Piezoelectricity gave way to quartz crystal microbalances (QCM), of which high-frequency QCMs (HFF-QCM 100MHz) are still being researched. In this paper, we use DNA immobilization on a HFF-QCM via self-assembled monolayers (SAM) technique. Immobilization was initially verified with ATR-FTIR. Then, DNA was immobilized in real time on the HFF-QCM crystals. A variation in the phase of the signal suggests fixation of DNA to the surface, in accordance with ATR-FTIR results. A density of 629 ng/cm2 was computed. Also, a positive correlation between immobilized DNA and DNA concentration, and the appearance of a saturation point between 1 and 5 μM were shown after analysis of different DNA concentrations.


2020 ◽  
Vol 3 (6) ◽  
pp. 5687-5697 ◽  
Author(s):  
Roto Roto ◽  
Aditya Rianjanu ◽  
Annisa Rahmawati ◽  
Innas Amaliya Fatyadi ◽  
Nursidik Yulianto ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document