scholarly journals The Pennsylvania Longitudinal Study of Parents and Children (PALSPAC) Twin Registry

2019 ◽  
Vol 22 (6) ◽  
pp. 765-768
Author(s):  
Amanda M. Ramos ◽  
Tong Chen ◽  
Peter K. Hatemi ◽  
H. Harrington Cleveland ◽  
Jenae M. Neiderhiser
Keyword(s):  
Longitudinal Study ◽  
Birth Cohort ◽  
Representative Sample ◽  
The State ◽  
Multiple Births ◽  
Future Directions ◽  
Department Of Health ◽  
Study Recruitment ◽  
Twin Registry ◽  
Parents And Children

AbstractThe Pennsylvania Longitudinal Study of Parents and Children Twin Registry was developed to capture a representative sample of multiple births and their parents in the state of Pennsylvania. The registry has two main efforts. The first began in 2012 through recruitment of adolescents in Pennsylvania schools. The second effort began in January 2019 in partnership with the Pennsylvania Department of Health to capture the birth cohort of twins born from 2007 to 2017. Study recruitment, sample demographics, focus and measures are provided, as well as future directions.

Arizona Reopening Phase 2: Rise and Fall of COVID-19 Cases

2021 ◽  
Vol 6 (5) ◽  
Keyword(s):  
United States ◽  
Longitudinal Study ◽  
Health Services ◽  
The United States ◽  
The State ◽  
Acquired Immunity ◽  
Phase 2 ◽  
Department Of Health ◽  
The World ◽  
Data Source

Of the United States 50 states, Arizona is the sixth largest in size. It is about the same size as Italy. After three months of Arizona Reopening Phase 2, the COVID-19 cases had surged. In early January 2021, ABC and NBC News reported that Arizona has the highest new cases per capital in the world. This longitudinal study examined the Arizona’s Reopening Phase 2 surge in cases. The study examined the changes in the numbers of testing given, new COVID-19 cases, cases that required hospitalizations, deaths, and vaccines given. The data source used was from the Arizona Department of Health Services COVID-19 dashboard database. During the last third of seven-month study period, Arizona’s case numbers declined as the number of those infected recovered and acquired immunity and the state residents became fully vaccinated increased.

scholarly journals Generation of a cleaned dataset listing Avon Longitudinal Study of Parents And Children peer-reviewed publications to 2015

2018 ◽  
Vol 3 ◽  
pp. 161 ◽  
Author(s):  
Oliver Butters ◽  
Amran Ismail ◽  
Sue Thompson ◽  
Rebecca Wilson
Keyword(s):  
Longitudinal Study ◽  
Cohort Studies ◽  
Birth Cohort ◽  
Research Data ◽  
Data Set ◽  
Parents And Children ◽  
Bibliometric Research ◽  
The Impact ◽  
Avon Longitudinal Study ◽  
Accurate Reporting

Birth cohort studies generate huge amounts of data, and as a consequence are a source of many peer reviewed publications. We have taken the list of publications from the Avon Longitudinal Study of Parents and Children UK birth cohort, filtered, de-duplicated and cleaned it to generate a bibliographic research data set. This dataset could be used for accurate reporting and monitoring of the impact of the study as well as bibliometric research.

scholarly journals Early Childhood General Anesthesia and Neurodevelopmental Outcomes in the Avon Longitudinal Study of Parents and Children Birth Cohort

2020 ◽  
Vol 133 (5) ◽  
pp. 1007-1020
Author(s):  
Graham J. Walkden ◽  
Hannah Gill ◽  
Neil M. Davies ◽  
Alethea E. Peters ◽  
Ingram Wright ◽  
...  
Keyword(s):  
Early Childhood ◽  
Longitudinal Study ◽  
General Anesthesia ◽  
Birth Cohort ◽  
Dynamic Balance ◽  
Statistical Significance ◽  
P Value ◽  
Neurodevelopmental Outcomes ◽  
Parents And Children ◽  
Avon Longitudinal Study

Background Most common anesthetic agents have been implicated in causing neurodegeneration in the developing animal brain, leading to warnings regarding their use in children. The hypothesis of this study was that exposure to general anesthesia and surgery before 4 yr would associate with adverse neurodevelopmental outcomes at age 7 to 16 yr. Methods This cohort study comprised 13,433 children enrolled in the Avon Longitudinal Study of Parents and Children, a prospective, population-based birth cohort born between 1991 and 1993 in southwest England. Children were grouped by none, single, or multiple exposures to general anesthesia and surgery by 4 yr. Motor, cognitive, linguistic, educational, social, and behavioral developmental outcomes were evaluated at 7 to 16 yr using school examination results, validated parent/teacher questionnaires, or clinic assessments. Continuous outcomes were z-scored. P-value thresholds were corrected using false discovery rate procedures. Results This study compared 46 neurodevelopmental outcomes in 13,433 children: 8.3% (1,110) exposed singly and 1.6% (212) exposed multiply to general anesthesia and surgery. Of these, the following reached predefined levels of statistical significance (corrected P < 0.00652): dynamic balance scores were 0.3 SD (95% CI, 0.1, 0.5; P < 0.001) lower in multiply exposed children; manual dexterity performance was 0.1 SD (95% CI, 0.0, 0.2; P = 0.006) lower in singly and 0.3 SD (95% CI, 0.1, 0.4; P < 0.001) lower in multiply exposed children; and social communication scores were 0.1 SD (95% CI, 0.0, 0.2; P = 0.001) and 0.4 SD (95% CI, 0.3, 0.5; P < 0.001) lower in singly and multiply exposed children, respectively. General anesthesia and surgery were not associated with impairments in the remaining neurodevelopmental measures including: general cognitive ability; attention; working memory; reading, spelling, verbal comprehension and expression; behavioral difficulties; or national English, mathematics, and science assessments (all ≤0.1 SD; corrected P ≥ 0.00652). Conclusions Early childhood general anesthesia and surgery were not associated with a global picture of clinically and statistically significant neurodegenerative effects, providing reassurance about the neurotoxic potential of general anesthesia. Exposure to anesthesia and surgery was associated with significantly lower motor and social linguistic performance. Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New

Arizona and COVID-19

2020 ◽  
Vol 5 (Special) ◽  
Keyword(s):  
United States ◽  
Longitudinal Study ◽  
Health Services ◽  
The United States ◽  
The State ◽  
Department Of Health ◽  
Data Source

Of the United States 50 states, Arizona is the sixth largest in size. It is about the same size as Italy. After six weeks of reopening the state, the COVID-19 cases had spiked. Arizona’s state COVID-19 ranking had rose from one of the states with the lowest number of reported cases to the top 7th in the total reported cases. The state took aggressive actions to address the rising cases. This longitudinal study examined the impacts of the actions taken. The study examined the changes in the numbers of new reported COVID-19 cases, the number of cases that required hospitalization, and the number of deaths. The data source used was from the Arizona Department of Health Services COVID-19 dashboard database. During the two-month study period, Arizona aggressive actions had slowed down the overall state rates of new COVID-19 cases and number of deaths.

scholarly journals Joint associations of parental personality traits and socioeconomic position with trajectories of offspring depression: findings from up to 6925 families in a UK birth cohort.

2020 ◽  
Author(s):  
Tim Cadman ◽  
Alex Siu Fung Kwong ◽  
Paul Moran ◽  
Heather O'Mahen ◽  
Iryna Culpin ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Longitudinal Study ◽  
Personality Traits ◽  
Birth Cohort ◽  
Socioeconomic Position ◽  
Effect Modification ◽  
Absolute Increase ◽  
Parents And Children ◽  
Parental Personality ◽  
The Impact

Background: Parental personality may influence the course of offspring depression but this is unclear. It is also unknown whether the impact of parental personality on offspring depression is moderated by socioeconomic position (SEP). Our aims were to describe trajectories of depressive symptoms across adolescence for offspring of parents with and without maladaptive personality traits and to test for effect modification by SEP. Methods: A longitudinal study in the Avon Longitudinal Study of Parents and Children birth cohort (ALSPAC; ns= 3054 to 7046). Exposures were binary measures of maladaptive parental personality traits and the outcome was depressive symptoms ages 11 to 24 (SMFQ; range 0 to 26). Results: Offspring of mothers with high maladaptive traits showed higher levels of depressive symptoms at all ages (SMFQ difference at age 10 = 0.66, CI 0.25, 1.28, p = 0.02; age 22 = 1.00, CI 0.51, 1.50, p < 0.001). There was weaker evidence of an association between paternal maladaptive personality traits and offspring depressive symptoms (SMFQ difference at age 10 = 0.21, CI -0.58, - 0.99, p = 0.60; age 22 = 0.02, CI -0.94, 0.90, p= 0.97). We found no consistent evidence of effect modification by SEP. Conclusions: Offspring of mothers with high levels of maladaptive personality traits show evidence of greater depressive symptoms throughout adolescence although the absolute increase in symptoms is small. Evidence for the effect of fathers personality was weaker. Socioeconomic position and maladaptive personality traits appear to be independent risk factors.

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