scholarly journals Genetic Influence on Accessory Navicular Bone in the Foot: A Korean Twin and Family Study

2017 ◽  
Vol 20 (3) ◽  
pp. 236-241 ◽  
Author(s):  
In Yae Cheong ◽  
Hyo Jeong Kang ◽  
Hyeonyoung Ko ◽  
Joohon Sung ◽  
Yun-Mi Song ◽  
...  

An accessory navicular bone (AN) is the most common accessory ossicle in the foot. The presence of an AN bone can trigger various foot problems, such as posterior tibial tendon pathology, flattening of the medial longitudinal arch, and medial foot pain. Despite the clinical influence of presence of an AN in foot disease, the research regarding its inheritance is still insufficient. A total of 135 pairs of monozygotic (MZ) twins, 25 pairs of dizygotic (DZ) twins, and 676 singletons from families were enrolled in order to estimate genetic influences on AN. After confirmation of zygosity and family relationship with a tandem repeat marker kit and questionnaires, the presence and type of the AN was classified through bilateral feet radiographic examination. The heritability of an AN was estimated using quantitative genetic analysis based on a variance decomposition model considering various types of family relationships: father–offspring pair, mother–offspring pair, and pooled DZ twin and sibling pairs. As a result, approximately 40.96% of the participants in this study had an AN in either foot, with type II being the most common type. The heritability for the presence of any type of an AN in any foot was estimated as 0.88 (95% CI [0.82, 0.94]) after adjusting for age and sex. Specifically, type II AN showed the highest heritability of 0.82 (95% CI [0.71–0.93]). The high heritability of an AN found in this large twin and family study suggests that an AN is determined by the substantial influence of genetic factor.

2021 ◽  
Author(s):  
Xu Tao ◽  
Qian dong Yang ◽  
Zhenyu Wang ◽  
Wei Wang ◽  
Kang Lai Tang

Abstract Background Patients with type II accessory navicular (AN) originally complain of the medial pain of foot. With increasing frequency, some of them has been recognized flexible flatfoot (FFF) at the first weightbearing radiographic examination. Posterior tibial tendon (PTT) dysfunction is widely accepted as a significant contributor to FFF. However, the PTT was not affected in these patients. The relationship between AN and FFF remains controversial. The contribution of AN to FFF was designed in this study. Methods Adult patients who complained of medial pain and bone eminence between January 2014 and January 2020 were included. 61 patients were confirmed to have the AN with flatfoot and randomly divided into two operative groups. The AN was excised in Group A, and the PTT was reconstructed to the navicular region with an anchor in Group B. Preoperative and postoperative evaluations were performed, including clinical evaluations, the American Orthopedic Foot and Ankle Society (AOFAS) mid-foot scale, a visual analog scale (VAS) and radiographic assessments of Meary’s angle, Pitch angle, talonavicular coverage, Kite’s angle and naviculocuboid overlap. PTT decline angle (PDA) and AN-Navicular joint inclination angle (ANJCA) in the lateral view were designed to evaluate the effect of AN on FFF. Results Fifty-six patients (56 feet) were included in this study because 5 patients were excluded. The mean follow-up period was 22.29 months with single excision (Group A) and 20.86 months with Kidner procedure (Group B). The AOFAS mid-foot score improved from 70.39±7.78 pre-operationally to 89.46±7.06 at the last follow-up in Group A and from 67.14±8.14 pre-operationally to 89.64±6.88 at the last follow-up in Group B. The VAS score decreased from 2.82±0.39 and 2.86±0.36 to 0.89±0.31 and 0.79±0.42, respectively. The radiographic results representing flatfoot significantly increased in the two groups. In the lateral view, PDA significantly increased after the operation, and the effect of PTT on the arch upward was induced by pull angulations and shorter distances. Conclusion The FFF with AN may be induced by AN and its synchondrosis. The weakened plantar ligament of synchondrosis was impaired under chronic tension and shear forces may be implicated as the etiologic biomechanical mechanism. AN excision or it with PTT reconstruction could release the pain and benefit the PTT pulling sufficiency.


Author(s):  
I. Gusti Ngurah Wien Aryana ◽  
I. Made Arditya Dwi Yudistira

Accessory navicular bone (ANB) is present in 4-20% of the general population. It can cause of midfoot pain and consequently may lead to flat foot. The patient usually presents with pain and swelling on the medial aspect of the foot with difficulty on walking. Diagnosis is often delayed. We report a case of symptomatic accessory navicular on a 30 years old female patient who complained of pain in the medial area of left foot for 2 years, and the pain getting worse in the last 2 weeks. Accessory navicular bone treatment may be non-surgical or surgical treatment in order to improve the symptoms. The following may be used: immobilisation by plaster splint, use of boots when walking, which allow the affected area to rest and reduce inflammation, use of an ice bag covered with a thin towel applied on the affected area in order to reduce swelling, oral non-steroidal anti-inflammatory drugs (NSAID). Surgical treatment of this condition involves removing the accessory bone (this additional bone is not necessary for normal foot function), remodeling the area, and repairing the posterior tibial tendon to improve its function. The most commonly used procedure to treat the symptomatic accessory navicular is Kidner procedure. The accessory navicular is a commonly occurring deformity that, because of its significant accompanying pathomechanical considerations, is closely associated with the pathologic flexible flatfoot. By recognizing and treating this progressive, debilitating deformity, both conservatively and surgically, the astute practitioner will be able to resolve discomfort, improve dysfunction, and restore quality of life.


2004 ◽  
Vol 48 (2) ◽  
pp. 267-271 ◽  
Author(s):  
Leigh D Mosel ◽  
Evelyn Kat ◽  
Frank Voyvodic

2004 ◽  
Vol 5 (4) ◽  
pp. 274 ◽  
Author(s):  
Yun Sun Choi ◽  
Kyung Tai Lee ◽  
Heung Sik Kang ◽  
Eun Kyung Kim

Law and World ◽  
2020 ◽  
Vol 14 (1) ◽  
pp. 163-177

The research shows that one of the legal relations in civil matters is the family relationship, having an extensive content. It includes Family Law and the actual family relationships. While there are factual elements in the family relationships, only marriage registration gives rise to the property and personal rights between spouses since marriage is a legal fact of law. However, it has been stated correctly in the legal literature that the actual co-existence of partners is such a family relationship, in which couples enter into marriage without registration. The inner world of unmarried couples is significantly free from legal regulation. Family relationships, by their characteristics, are inconceivable without the personal and intimate aspects contained in certain factual foundations and found in family relationships.


2021 ◽  
pp. 194855062110183
Author(s):  
Sandra L. Murray ◽  
Mark D. Seery ◽  
Veronica M. Lamarche ◽  
Han Young Jung ◽  
Thomas L. Saltsman ◽  
...  

Elections and pandemics highlight how much one’s safety depends on fellow community members, a realization that is especially threatening when this collective perceives political realities inconsistent with one’s own. Two longitudinal studies examined how people restored safety to social bonds when everyday experience suggested that fellow community members inhabited inconsistent realities. We operationalized consensus political realities through the negativity of daily nationwide social media posts mentioning President Trump (Studies 1 and 2), and the risks of depending on fellow community members through the pending transition to a divided Congress during the 2018 election season (Study 1), and escalating daily U.S. COVID-19 infections (Study 2). On days that revealed people could not count on fellow community members to perceive the same reality of President Trump’s stewardship they perceived, being at greater risk from the judgment and behavior of the collective community motivated people to find greater happiness in their family relationships.


2020 ◽  
Vol 3 (2) ◽  
pp. 32-40
Author(s):  
Desak Gede Yenny Apriani

Background: Children develop very traumatic and anxious experiences during the infusion process. The role of finance for children in hospitals is related to collaboration between family and nurses or doctors with financial participation in meeting children's needs and care by providing emotional support for children.Objective: This study discusses family relationships with children during infusion of teenage children (12-18 years).Method: The design of this study used a cross sectional study using observational. The samples used were school-age children 12-18 years old who were to take intravenous measures at the BRSU IRD Room in Tabanan Regency.Results: Most respondents who did not get anxious were 55 (38.8%) respondents and family recipients who received 107 (79.9%) respondents. Based on the results of the Spearman rank test the results of the r value are 0.604 and the value of p 0.000 means that there is a family relationship with the children during infusion in adolescents (12-18 years) in the BRSUD Room in Tabanan Regency.Conclusion: Family support provides a strong level of ability for children when installing IVs.


2001 ◽  
Vol 121 (9) ◽  
pp. 546-547 ◽  
Author(s):  
I˙. Günal ◽  
K. Yörüko˘glu

2019 ◽  
Vol 5 (4) ◽  
pp. 806-808
Author(s):  
Alioune Badara Gueye ◽  
Mouhamadou Niane ◽  
Charles Valérie Alain Kinkpé ◽  
Abdoulaye Ndoye Diop ◽  
Mohamed Daffé ◽  
...  

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