e17530 Background: Prostate cancer (CP) is one of the most common malignant neoplasms among men with high prevalence worldwide. In Brazil, in 2019, 582,000 new cases of cancer were estimated, 282,000 in women and 300,000 in men, 75% are prostate cancer in individuals over 65 years of age (BRASIL, 2019). The occurrence of CP has specific risk factors, such as advanced age (over 65 years), genetic predisposition (patients with a family history of prostate cancer, between 35 and 40 years of age) and ethnicity (mostly blacks). Mortality due to this neoplasm is considered relatively low compared to other types of cancers, which partly reflects a good prognosis.The objective of this study is to describe the epidemiological profile of prostate cancer patients treated in an Muriae Cancer hospital in Minas Gerais - Brazil. Methods: Descriptive cross-sectional study conducted between 1997 and 2019 with 4,395 patients diagnosed with CP, living in the region and adjacencies, 4,175 (95%) assisted by the Unified Health System (SUS). Results: Patients from Minas Gerais-Brazil, cities of microregions and rural areas, the most prevalent age group was between 61-70 years of age with 1769 cases (40.25%), 3476 (79.1%) with low schooling, 3156 (71.82%) with per capita family income less than 0.5 minimum wages, and in regarding profession, the majority 541 (58.05%) is retired and rural workers 148 (15.88%); 1933 (44%) alcohol users, 2021 (46%) smokers and 1626 (37%) with a report of a family history of cancer. As for ethnicity, 1943 (44.23%) were black. Nutritional status 3845 (87.49) were eutrophic. The mean time between diagnosis and treatment was 51 months. PSA levels were 1ng/ml to 10 ng/ml (39%), from 10 ng/ml to 28 ng/ml (21%), from 28 ng/ml to 70 ng/ml (9%) and from 70 ng/ml to 200 ng/ml (6%) and > 200 ng/ml (5%); altered tests 1845 (42%), PSA elevation 1538 (35%), obstructive symptoms 965 (5%), dysuria 579 (3%) and pain 579 (3%). The majority (50.41%) with stage II, stage III (18.10%) and IV (9%), highlighting that in 1997 the percentage of advanced stages (III and IV) was 47% and in 2019 it decreased to 18%, due to earlier diagnoses. Conclusions: The analyzed data allowed to characterize the epidemiological and sociodemographic profile of patients treated in Muriaé Cancer hospital, Brazil, contributing to decision-making regarding the treatment provided to this population.