scholarly journals (A121) Relation of Dopamine Dependent Hypotension with Outcome in Cervical Spine Injury Patients

2011 ◽  
Vol 26 (S1) ◽  
pp. s34-s34
Author(s):  
A. T. D. Agarwal

BackgroundIt is believed that dopamine resistance sets in within 72–92 hours following therapy. However, in the authors' experience, spinal cord injury patients may require dopamine to maintain blood pressure over several weeks.ObjectivesThis study aims to: (1) assess the incidence and duration of of dopamine dependence in cervical cord injury patients; and (2) find the relation (if any) of dopamine dependent hypotension with outcome of spinal cord injured patients.MethodsThis was a prospective, observational study carried out over 2-month period in the neurosurgery intensive care unit (ICU) at JPN Apex Trauma Centre, AIIMS. All cervical spine injury patients who had hypotension during the hospital stay were included in the study. History, clinical findings, requirement of ionotropic support, management, and outcome were recorded for all enrolled subjects.ResultsDuring the study period 48 patients were admitted with cervical spine injury in the ICU. Of these, 26 patients (54%) had hypotension and were constituted the study group. Eleven patients had complete spinal cord injury (power 0/5) and 15 patients had incomplete spinal cord injury. Twenty-four patients were on ventilator support and two were on oxygen masks. The mean dose of dopamine which the patient receives during the treatment was 7.5 mcg/kg/min with the maximum and minimum doses of 20mcg/kg/min and 2 mcg/kg/min. The mean duration of dopamine support was 17 days (Range 6–48 days). Eight patients (31%) required intermittent dopamine support and 18 patients (70%) required continuous support. The in-hospital mortality was 61% (n = 16). Mortality was significantly lower in patients who received intermittent ionotropic support as compared to those who required continuous ionotropic support (p < 0.01).ConclusionThe patients with spinal cord injury are dependent on dopamine throughout their recovery period. The patients who required intermittent ionotropic support had significant better outcome compared to those who required continuous ionotropic support.

Author(s):  
Hideo Iida ◽  
Shigekuni Tachibana ◽  
Takao Kitahara ◽  
Shigeharu Horiike ◽  
Takashi Ohwada ◽  
...  

2018 ◽  
Vol 1 (3) ◽  
Author(s):  
Gede Andry Nicolas ◽  
Heru Sutanto Koerniawan ◽  
Tjokorda Gde Bagus Mahadewa

The incident of cervical spine injury and cervical spinal cord injury is between 2.0% to 5.0%. The advanced trauma life support (ATLS) stated that a patient with multiple traumas should be assumed tohave cervical spine injury especially if the patient loses consciousness when present in the ER. It is stressed that cervical spine injury requires continuous immobilization of the patient’s entire body using a semirigid collar as well as a backboard with tape and straps before and during transfer to a defnitive care facility. The understanding of the mechanism of injury is the most important as the forces transferred are signifcantly different causing different injuries. A serial case reported by Walter and Adkins found that there was no signifcant difference between the patients that have a bullet removed from the neck and patients that have a bullet left in the cervical cord. In both cases, there was no improvement to the neurologic outcome. Kupcha recommends doing selective wound management and observation of retained intracanal bullet fragments in a patient with complete lesion. Surgical decompression after the injury is not recommended. We report a case of 14 year old boy who was treated at Sanglah Hospital referred froman out-of-island Type C Hospital with a spinal cord injury - American Spinal Injury Association A (SCI ASIA A) caused by a gunshot wound in the cervical. Surgical decompression and bullet removal was performedas well as fusion stabilization. He is then treated in the intensive care unit for 48 hours with a slight improvement in motoric of upper and lower extremities.


1992 ◽  
Vol 41 (1) ◽  
pp. 327-329
Author(s):  
Kiyoshi Uchino ◽  
Takashi Sakou ◽  
Nagatoshi Yoshikuni ◽  
Kazunori Yone ◽  
Hiroshi Itou ◽  
...  

Neurosurgery ◽  
2019 ◽  
Vol 66 (Supplement_1) ◽  
Author(s):  
Haddy Alas ◽  
Avery Brown ◽  
Katherine Pierce ◽  
Cole Bortz ◽  
Michael Moses ◽  
...  

Abstract INTRODUCTION As youth athletic sports continue to be played at a highly competitive level, more attention is called to potentially fatal cervical spine injuries. METHODS KID was queried for patients with E-Codes (ICD-9-CM codes) pertaining to external causes of injury secondary to sports-related activities from 2003 to 2012. Patients were further grouped by cervical spine injury type [C 1-4 and C 5-7 fracture with and without spinal cord injury (SCI), dislocation, and SCI without radiographic abnormality (SCIWORA). Patients were grouped by age into children (4-9), preadolescents (pre,10-13), and adolescents (14-17). Sports included by E-Code: American football, other team sports, individual, winter, water, and martial arts. Kruskall–Wallis tests with posthocs identified differences in cervical injury type across age groups and sports. Logistic regression assessed predictors of traumatic brain injury (TBI) and cervical injury type. RESULTS A total of 38 539 pts with sports injuries were identified (12.76 yr, 24.5% F). Adolescents had the highest rate of sports injuries per year, but rates decreased in pre and adolescents and increased in children. Adolescents had the highest rate of any type of cervical spine injury and TBI. Adolescence increased odds for C 1-4 fx with and without SCI, C 5-7 fx with and without SCI, cervical dislocation, and cervical SCIWORA (all P < .05). Cervical fx of any type tended to occur in disproportionately higher rates via team, winter, or water sports (P < .001). Martial arts had significantly higher rates of cervical dislocations compared to other sports (P = .039). Football injuries rose from 5.83% to 9.14% (2009-2012) (P < .001) and had significantly more SCIWORA than non-football sports (1.6 vs 1.0%, P = .012). Football increased odds of SCI by 1.56x compared to any other sport (OR: 1.56 [1.11-2.20], P = .011). SCIWORA was a significant predictor for concurrent TBI across all sports (OR: 2.35[1.77-3.11], P < .001). CONCLUSION Adolescent athletes had the highest rates of upper/lower cervical fracture, dislocation, and SCIWORA. Adolescence and SCIWORA were significant predictors of concurrent TBI across sports.


2021 ◽  
Vol 12 (2) ◽  
pp. 92-97
Author(s):  
Sushant H Bhadane ◽  

Background: The consequences of cervical spine injuries range from simple neck pain, to quadriplegia, or even death. MR imaging has become part of the diagnostic and prognostic tools for spinal cord injury. Aim: To prospectively evaluate cervical spine injuries by MR imaging and to find out association of MR imaging findings with degree of neurological deficit. Material and Methods: Descriptive longitudinal hospital based study was conducted on 30 patients with known or suspected cervical spine trauma who presented to the emergency department. Results: Mean age of the cases was about 42 years, with female to male ratio of 1:6.5. C6-C7 spinal level was most commonly involved. Proportions complete spinal cord injury (CSCI), incomplete spinal cord injury (ISCI) and neurologically normal (NN) were 23.33%, 60% and 16.67% respectively. Out of 12 MRI findings, cord haemorrhage, contusion, posterior element fracture, disc injury, prevertebral hematoma, subluxation and soft tissue injury was statistically associated with degree of neurological deficit. Cord contusion, cord haemorrhage and posterior element fracture were potential predictors of neurological status at admission. Cord contusion, cord haemorrhage and subluxation were potential predictors at 3 months. Conclusion: MRI proved a pivotal role in the diagnosis of SCIs, deciding prompt management and predicting neurological deficit and prognosis of neurological recovery. So, MRI is an excellent diagnostic modality for the evaluation of spinal trauma and predicting the degree of neurological deficit and recovery.


2020 ◽  
pp. 1-5
Author(s):  
Theresa L. Williamson ◽  
Andrew Cutler ◽  
Mary I. Cobb ◽  
Shervin Rahimpour ◽  
Eric R. Butler ◽  
...  

This study describes a patient with an autograft-derived spinal cord mass following transplantation of olfactory mucosa for treatment of cervical spine injury. The authors report the case of a 35-year-old man who suffered a complete spinal cord injury (SCI) at C5–6 in 2001. The patient underwent an olfactory mucosal cell implantation at the location of injury 4 years following initial trauma. Twelve years later, the patient presented with rapidly progressive decline in upper-extremity function as well as neuropathic pain. Imaging revealed a heterogeneously enhancing intramedullary mass from C3 to C7. At surgery, the patient was found to have a posttransplant mucinous mass. Each mucinous cyst was drained and a portion of the cyst wall was removed. Histological examination demonstrated ciliated epithelium-lined fibrous tissue, submucosal glands, and mucoid material, consistent with a transplant-derived tumor. This case report both documents a rare long-term complication of olfactory mucosal cell transplantation and serves as a cautionary tale encouraging prudent use of novel treatments in a vulnerable population of patients with severe SCI.


Neurosurgery ◽  
1986 ◽  
Vol 19 (6) ◽  
pp. 1038-1040 ◽  
Author(s):  
James E. Wilberger ◽  
Adnan Abla ◽  
Joseph C. Maroon

Abstract The burning hands syndrome of spinal cord injury was first described in 1977. The syndrome is characterized by burning dysesthesias and paresthesias in the hands and may be associated with either cervical fracture/dislocation or no detectable cervical spine abnormalities. A case of burning hands syndrome without cervical spine injury is presented in which somatosensory evoked potentials and magnetic resonance imaging were used to delineate the pathophysiology of this syndrome.


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