Levels of serum protein and antibodies to Brucella abortus in Finnish Landrace lambs

1966 ◽  
Vol 8 (2) ◽  
pp. 275-280 ◽  
Author(s):  
R. Halliday

The mean concentrations of total serum protein, γ-globulin and antibody were almost identical in groups of Finnish Landrace lambs from litters in which one, two or three, respectively, survived till the 3rd day. Lambs from two litters each with four survivors had considerably lower mean concentrations. Merino × Cheviot and Scottish Blackface lambs examined previously had significantly lower serum protein concentrations than the Finnish lambs and higher antibody levels in single than in twin lambs.

1996 ◽  
Vol 42 (8) ◽  
pp. 1189-1195 ◽  
Author(s):  
R S Rosenson ◽  
A McCormick ◽  
E F Uretz

Abstract Increases in the viscosity of blood and plasma predict clinical manifestations of atherothrombotic vascular disease. The clinical utility of viscosity measurements in cardiovascular risk factor analysis requires reference values established from a healthy disease-free population. A cohort of 126 (71 men, 55 women) healthy nonsmoking adults had fasting blood analysis after a 12-14-h fast. Viscosity measurements were made on samples of whole blood, plasma, and serum at 37 degrees C with a coaxial cylinder microviscometer. The mean blood viscosity at shear rates of 100, 50, and 1 s-1 were 3.26 +/- 0.43, 4.37 +/- 0.60, and 5.46 +/- 0.84 mPa.s, respectively. Men had significantly higher blood viscosity values than women at each shear rate. The differences in blood viscosity did not remain significant after blood viscosity values were normalized to a hematocrit of 45%, except at 100 s-1. For the entire group, normalized blood viscosity values at each measured rate correlated inversely with HDL cholesterol and positively with fibrinogen. The mean plasma viscosity was 1.39 +/- 0.08 mPa.s and the mean serum viscosity was 1.27 +/- 0.06 mPa.s. Plasma viscosity correlated with fibrinogen (r = 0.51, P < 0.0001), total serum protein (r = 0.33, P < 0.0001), and triglyceride concentrations (r = 0.33, P < 0.0015). Serum viscosity correlated with total serum protein (r = 0.50, P < 0.0001) and LDL cholesterol (r = 0.24, P = 0.0065). This study provides reference values for the viscosity of blood, plasma, and serum that may assist in evaluating hemorheological profiles.


1970 ◽  
Vol 74 (1) ◽  
pp. 103-106 ◽  
Author(s):  
R. Halliday

SUMMARYTwenty-six Finnish Landrace × Scottish Blackface ewes, mated to a Dorset Horn ram, produced 58 lambs. Protein concentrations in the ewes' colostra during the first week of lactation, and in the ewes' and lambs' sera on the 3rd day after parturition were compared with those in pure-bred Finnish and Blackface sheep. In cross-bred and Blackface lambs the total serum protein and γ-globulin concentrations decreased significantly as litter-size increased. Litter-size had much less effect in Finnish lambs. When litters of the same size were compared, cross-bred lambs tended to have higher concentrations than Blackface lambs, but had much lower concentrations than Finnish lambs. The mean protein concentrations in sera and presuckling colostra from Finnish × Blackface ewes were almost exactly the same as in Finnish ewes, but were considerably lower and higher, respectively, than in Blackface ewes. When suckling began the concentrations in the colostra decreased much faster in Finnish ewes, even when ewes nursing the same number of lambs were compared. Differences in suckling behaviour on the day of birth may therefore partly account for the variations in the amounts of maternal protein obtained by lambs of different breeds.


1966 ◽  
Vol 12 (10) ◽  
pp. 709-716 ◽  
Author(s):  
Ulysses S Seal ◽  
Harold Eist

Abstract The mean concentration of each of the serum protein-bound carbohydrates (hexose, hexosamine, fucose, and sialic acid) was significantly elevated in a group of 60 male schizophrenic patients. The total serum protein was elevated, ceruloplasmin was normal, and C-reactive protein was absent. Serum haptoglobin was significantly elevated. The distribution of haptoglobin types was normal. Haptoglobin concentration variation was significantly correlated with each of the carbohydrates and, to a lesser degree, with ceruloplasmin. In a group of 13 patients with normal erythrocyte sedimentation rate, the fibrinogen and haptoglobin concentrations were significantly elevated. There was no correlation between haptoglobin and fibrinogen concentrations in this group.


1951 ◽  
Vol 29 (2) ◽  
pp. 48-58
Author(s):  
Christine E. Rice ◽  
Paul Boulanger ◽  
P. J. G. Plummer

To determine whether liver injury would result in a parallel decline in the complement titer and coagulative properties of the blood, groups of guinea pigs were given series of injections of the liver poison, carbon tetrachloride. Marked fatty degeneration of the liver, a decline in total serum protein and albumin, a decrease in complement activity, and a prolongation of coagulation time was observed in the treated animals. A general relationship was noted between the albumin-globulin ratio and the complement titer of the serum and between the complement titer and the coagulation time of the plasma.


1967 ◽  
Vol 24 (11) ◽  
pp. 2339-2354 ◽  
Author(s):  
James E. Stewart ◽  
John W. Cornick ◽  
Diane M. Foley ◽  
M. F. Li ◽  
C. M. Bishop

Total serum protein values, hemocyte numbers, and muscle weights were determined for 216 intermolt lobsters immediately after their capture, and for 230 others held captive under a variety of dietary and environmental conditions. Average muscle values ranged from approximately 13% to the more normal 20–25% of the live animals' weight, depending upon experimental conditions. The total serum protein up to a level of 55 mg/ml was shown to be a reliable indicator of muscle weights, although the relationship was not identical for all lobster groups. It appeared to be modified chiefly by the areas from which the different groups were taken. Diet was more important than the temperatures (5 to 14 C) in affecting changes in muscle and serum protein values. Starvation caused a greater reduction (50 to 70%) in the size of the hepatopancreas than in the muscle. Histological examination of the hepatopancreatic tissue showed that the lipid content was markedly reduced upon starvation and that a degeneration of this organ was apparent for lobsters fed a beef liver and herring diet. Measurement of serum proteins would appear to be a useful technique in experiments on lobster nutrition and have value, within specified limits, for assessing the physiological condition of wild lobsters.


1967 ◽  
Vol 45 (4) ◽  
pp. 571-575 ◽  
Author(s):  
W. F. Blatt ◽  
J. Kerkay

Total protein, serum protein, and lipoprotein electrophoretic distribution and hematocrit values were determined in two groups of men during acclimatization to 6 weeks of cold and 11 days of heat respectively. After 3 weeks of cold exposure total serum protein and albumin content decreased, while the globulin fractions increased; thus, the calculated albumin/globulin ratio was significantly depressed. During the last 2 weeks, these parameters gradually returned to control values. Overall, the protein changes during heat acclimatization were minimal, although the globulins decreased slightly, yielding a small increase in the albumin/globulin ratio. The hematocrit levels were significantly lowered during both environmental exposures, whereas the lipoprotein distribution remained essentially unchanged.


2019 ◽  
Vol 71 (2) ◽  
pp. 363-368
Author(s):  
A.F. Souza ◽  
J. Schade ◽  
A.F. Ramos ◽  
M.S.M. Albuquerque ◽  
G.V. Fonteque ◽  
...  

ABSTRACT The aim of this study to measure the fractions of the total serum proteins of the Campeiro horse and identify the influences of biological variants. Blood samples were taken in 138 horses of the breed Campeiro for measuring the concentration of total serum protein by the biuret method. Serum concentrations of protein fractions were measured by electrophoresis using agarose gel. Groups were formed according to age, sex and reproductive condition. The average values of serum fractions: albumin (2.85±0.36g/dl), alpha 1 (0.28±0.11g/dl), alpha 2 (0.26±0.08g/dL) beta 1 (0.57±0.15g/dl), beta 2 (0.89±0.28g/dL), gamaglobulinas (1.86±0.34g/dL), albumin/globulin ratio (0.75±0.18) and 2.5% percentile and 97.5% had slight differences in relation to the reference interval proposed for the species. They observed higher values of alpha 1 and 2 globulins in the group from that had six to eight years old and gammaglobulins in group above 13 years old. Serum protein concentrations were similar in horses and mares and between non-pregnant and pregnant. Sex and pregnancy status did not affect serum proteinogram. Alpha and gammaglobulins have higher values as the age increases. Serum proteinogram of Campeiro horses shows variations that have to be considered in the interpretation of laboratory tests.


1971 ◽  
Vol 17 (4) ◽  
pp. 301-306 ◽  
Author(s):  
John Savory ◽  
M Geraldine Heintges ◽  
Robert E Sobel

Abstract An automated continuous-flow procedure has been developed for simultaneously measuring total serum protein and globulin. The method for total protein is a minor modification of an existing automated method in which the biuret reagent is used. Total globulin is measured by reaction with glyoxylic acid, and standardized with N-acetyltryptophan. An empirical factor relating concentration of N-acetyltryptophan to human globulin has been derived. Values for total serum globulin obtained by this new automated procedure correlate closely with values obtained by electrophoresis, but do not agree with values obtained by use of procedures involving binding of anionic dye. Recovery of gamma globulin added to serum is essentially quantitative; the day-to-day precision (CV) is 4.31%.


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