scholarly journals The effects of cannabis use on salience attribution: a systematic review

2016 ◽  
Vol 30 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Surapi Bhairavi Wijayendran ◽  
Aisling O’Neill ◽  
Sagnik Bhattacharyya
Keyword(s):  
Brain Regions ◽  
Cannabis Use ◽  
Cognitive Tasks ◽  
Indirect Measures ◽  
Neural Processes ◽  
Aberrant Salience ◽  
And Performance ◽  
The Relationship ◽  
Chronic Use

ObjectiveThe relationship between cannabis use and the onset of psychosis is well established. Aberrant salience processing is widely thought to underpin many of these symptoms. Literature explicitly investigating the relationship between aberrant salience processing and cannabis use is scarce; with those few studies finding that acute tetrahydrocannabinol (THC) administration (the main psychoactive component of cannabis) can result in abnormal salience processing in healthy cohorts, mirroring that observed in psychosis. Nevertheless, the extent of and mechanisms through which cannabis has a modulatory effect on aberrant salience, following both acute and chronic use, remain unclear.MethodsHere, we systematically review recent findings on the effects of cannabis use – either through acute THC administration or in chronic users – on brain regions associated with salience processing (through functional MRI data); and performance in cognitive tasks that could be used as either direct or indirect measures of salience processing. We identified 13 studies either directly or indirectly exploring salience processing. Three types of salience were identified and discussed – incentive/motivational, emotional/affective, and attentional salience.ResultsThe results demonstrated an impairment of immediate salience processing, following acute THC administration. Amongst the long-term cannabis users, normal salience performance appeared to be underpinned by abnormal neural processes.ConclusionsOverall, the lack of research specifically exploring the effects of cannabis use on salience processing, weaken any conclusions drawn. Additional research explicitly focussed on salience processing and cannabis use is required to advance our understanding of the neurocognitive mechanisms underlying the association between cannabis use and development of psychosis.

scholarly journals Green innovation, government incentive and enterprise performance are explored from the perspective of game

2021 ◽  
Vol 275 ◽  
pp. 02006
Author(s):  
Xiaohui Ren
Keyword(s):  
Game Theory ◽  
Rapid Development ◽  
Enterprise Performance ◽  
Green Innovation ◽  
Green Development ◽  
Pollution Problem ◽  
Environmental Pollution Problem ◽  
And Performance ◽  
The Relationship

The rapid development of economy brings serious environmental pollution problem. Green innovation, as the connection point between government environmental regulation measures and sustainable green development of enterprises, has become one of the important choices for the transformation and development of enterprises. Based on the classic model of “prisoner’s dilemma” in game theory, this paper deeply analyzes the relationship between green innovation and performance. It is found that it is easy to get into trouble if only relying on the spontaneous green innovation within the enterprise. Applying appropriate pressure outside the enterprise can promote the change of green innovation and bring long-term benefits to the enterprise.

Long-term medical cannabis use and risk factors for diversion: Report on physician's guidance and patients’ behaviour

2019 ◽  
Vol 18 (1) ◽  
pp. 18-23
Author(s):  
Sharon R. Sznitman ◽  
Victoria Goldberg ◽  
Hedva Sheinman-Yuffe ◽  
Yuval Zolotov ◽  
Ezequiel Flechter ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cannabis Use ◽  
Medical Cannabis ◽  
Safety Practices ◽  
Face To Face ◽  
Safe Storage ◽  
Regular Manner ◽  
Key Aspects ◽  
The Relationship

AbstractObjectivesVarious jurisdictions have legalized cannabis for medical purposes. As with all psychoactive medications, medical cannabis carries a risk of diversion and accidental ingestion. These risks may be particularly high among long-term medical cannabis patients as safety practices may become less salient to patients once the treatment becomes part of everyday life. The current study examines whether patients who have used medical cannabis for longer periods differ from those who have used for shorter periods in terms of sociodemographic background and other key aspects of medical cannabis use. Furthermore, the study examines the relationship between length of medical cannabis treatment and risk factors related to storage and diversion. Finally, the study examines the extent to which oncologists provide information to their patients about safe storage and disposal.MethodsOne hundred twenty-one medical cannabis oncology patients were interviewed face-to-face and 55 oncologists participated in a survey about safe storage and disposal practices related to medical cannabis.ResultsLength of medical cannabis treatment was related to administration by smoking and using higher monthly dosages. In terms of risk for unsafe storage and diversion, length of medical cannabis was positively associated with using cannabis outside the home and having been asked to give away medical cannabis. Physicians did not report providing information to patients regarding safe storage and disposal practices in a regular manner.Significance of resultsResults suggest that there is an ongoing risk of unsafe storage and diversion over the course of medical cannabis treatment. Oncologists may need to give more consistent and continued training in safe storage and disposal practices, especially among long-term medical cannabis patients.

Effect of Goal Proximity and Goal Specificity on Muscular Endurance Performance: A Replication and Extension

1991 ◽  
Vol 13 (2) ◽  
pp. 174-187 ◽  
Author(s):  
Gershon Tenenbaum ◽  
Saadia Pinchas ◽  
Gabi Elbaz ◽  
Michael Bar-Eli ◽  
Robert Weinberg
Keyword(s):  
High School Students ◽  
Endurance Performance ◽  
Experimental Period ◽  
Baseline Period ◽  
Short Term ◽  
School Students ◽  
Goal Specificity ◽  
And Performance ◽  
The Relationship

The purpose of the present investigation was to extend the literature on the relationship between goal specificity, goal proximity, and performance by using high school students and attempting to control for the effects of social comparison. Subjects (N=214) in Experiment 1 were randomly assigned to one of five goal-setting conditions: (a) short-term goals, (b) long-term goals, (c) short- plus long-term goals,(d) do-your-best goals, and (e) no goals. After a 3-week baseline period, subjects were tested once a week on the 3-minute sit-up over the course of the 10-week experimental period. Results indicated that the short- plus long-term group exhibited the greatest increase in performance although the short-term and long-term groups also displayed significant improvements. In Experiment 2, a short- plus long-term group was compared against a do-your-best group. Results again revealed a significant improvement in performance for the combination-goal group whereas the do-your-best group did not display any improvement.

scholarly journals Hysteresis effects of R&D expenditures and patents on firm performance: An empirical study of Hsinchu Science Park in Taiwan

Filomat ◽  
2016 ◽  
Vol 30 (15) ◽  
pp. 4265-4278 ◽  
Author(s):  
Shi-Zheng Huang ◽  
Tung-Ju Wu ◽  
Hsien-Tang Tsai
Keyword(s):  
Hysteresis Effect ◽  
Economic Effects ◽  
Var Model ◽  
Science Park ◽  
Stable Relationship ◽  
Innovation Capacity ◽  
Important Means ◽  
And Performance ◽  
The Relationship

R&D expenditures and patents are important means to improve an enterprises capacity in technological innovation, and are also drivers for sustainable development of a country. This study investigated R&D expenditures, patent quantity and performance of the top six industries in Taiwans Hsinchu Science Park for the period of 1988-2011. VAR model was used to analyze the relationship between R&D expenditures, patent and performance, and the hysteresis effect. The results showed that the governments R&D expenditures and patent quantity have a long-term and stable relationship with performance, as well as a positive correlation with performance, and a hysteresis effect on performance. The hysteresis effect of R&D expenditures and patents on performance is significantly different in different industries. These findings suggest that the governments R&D expenditures can bring economic effects to enterprises and improve enterprises innovation capacity. Thus, both government and enterprises should attach importance to R&D expenditures.

scholarly journals The Influence of Debt Financing on Firms’ Performance: Empirical Evidence from Malaysia

2021 ◽  
Vol 5 (1) ◽  
pp. 76-87
Author(s):  
Yien Yien Lee
Keyword(s):  
Fixed Effect Model ◽  
Short Term ◽  
Return On Assets ◽  
Causality Test ◽  
Listed Firms ◽  
Effect Model ◽  
Lm Test ◽  
And Performance ◽  
The Relationship

This study investigated the relationship between the listed firms’ debt level and performance in Bursa Malaysia during a five-year period. Based on the results of the Hausman test and Breusch-Pagan LM test, the fixed-effect model is the most appropriate model that used to analyze the panel data of 50 Malaysian listed companies within the property sector from the year 2015 to 2019. The results indicated that the short-term debt (STD) and long-term debt (LTD) have positive and insignificant effects on return on asset (ROA), which means that the increase in the short-term debt and long-term debt will lead to an increase in the return on assets. Besides that, account payables (AP) has a negative and insignificant effect on the profitability of property sector companies. According to the outcome of the Granger Causality test, the return on assets does not affect by the account payables, short-term debt, long-term debt and firm size. There is only one unidirectional causality relationship that proves that short-term debt is affected by long-term debt. Additionally, this study focuses on enhancing the existing empirical knowledge of debt financing's influence on the profitability of the listed firms in the property sector.

A Star Is Born: The Relationship Between Performance and Achieving Status Through Certification Contests in the Context of Equity Analysts

2022 ◽  
Author(s):  
Eugene Taeha Paik ◽  
Timothy G. Pollock ◽  
Steven Boivie ◽  
Donald Lange ◽  
Peggy M. Lee
Keyword(s):  
High Status ◽  
Short Term ◽  
Equity Analysts ◽  
Subsequent Performance ◽  
The Social ◽  
And Performance ◽  
The Relationship ◽  
Status Position ◽  
Over Time

We investigate how the relationship between status and performance decouples over time by addressing two questions: (1) how performance affects the likelihood that an actor achieves high status and (2) how achieving high status affects the actor’s subsequent performance. In doing so, we focus on the role repeated certification contests play, where evaluators assess actors’ performance along particular dimensions and confer high status on the contest winners. Using the context of sell-side (brokerage) equity analysts and the “All-Star” list from Institutional Investor magazine, we first investigate whether analysts who make the All-Star list are more likely to produce accurate and/or independent forecasts. Then, we investigate analyst performance after recent and multiple wins. Our results demonstrate the decoupling of status and performance over time and the roles played by both the high-status actor and the social evaluators conferring their status. Whereas analyst performance increases the likelihood of being designated an All-Star, recent and multiple All-Star designations differentially affect both how subsequent performance is assessed, and how the All-Star analysts subsequently perform. In the short term, achieving high status can increase performance and solidify an analyst’s status position; however, in the long term, it can lead to lower performance and eventually result in status loss, which further erodes performance.

scholarly journals Long-term consequences of childhood maltreatment: Altered amygdala functional connectivity

2015 ◽  
Vol 27 (4pt2) ◽  
pp. 1577-1589 ◽  
Author(s):  
Kelly Jedd ◽  
Ruskin H. Hunt ◽  
Dante Cicchetti ◽  
Emily Hunt ◽  
Raquel A. Cowell ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Functional Connectivity ◽  
Childhood Maltreatment ◽  
Brain Regions ◽  
Healthy Development ◽  
Early Stress ◽  
History Of ◽  
The Impact ◽  
The Relationship

AbstractChildhood maltreatment is a serious individual, familial, and societal threat that compromises healthy development and is associated with lasting alterations to emotion perception, processing, and regulation (Cicchetti & Curtis, 2005; Pollak, Cicchetti, Hornung, & Reed, 2000; Pollak & Tolley-Schell, 2003). Individuals with a history of maltreatment show altered structural and functional brain development in both frontal and limbic structures (Hart & Rubia, 2012). In particular, previous research has identified hyperactive amygdala responsivity associated with childhood maltreatment (e.g., Dannlowski et al., 2012). However, less is known about the impact of maltreatment on the relationship between the amygdala and other brain regions. The present study employed an emotion processing functional magnetic resonance imaging task to examine task-based activation and functional connectivity in adults who experienced maltreatment as children. The sample included adults with a history of substantiated childhood maltreatment (n = 33) and comparison adults (n = 38) who were well matched on demographic variables, all of whom have been studied prospectively since childhood. The maltreated group exhibited greater activation than comparison participants in the prefrontal cortex and basal ganglia. In addition, maltreated adults showed increased amygdala connectivity with the hippocampus and prefrontal cortex. The results suggest that the intense early stress of childhood maltreatment is associated with lasting alterations to frontolimbic circuitry.

The contrasting moderating effect of exploration on the relationship between stock options/stock ownership and a firm’s long-term performance

2018 ◽  
Vol 56 (9) ◽  
pp. 1956-1968 ◽  
Author(s):  
Gun Jea Yu ◽  
Joonkyum Lee
Keyword(s):  
Stock Options ◽  
Chief Executive ◽  
Moderating Effect ◽  
Stock Ownership ◽  
Content Type ◽  
And Performance ◽  
Long Term Performance ◽  
Term Performance ◽  
The Relationship

Purpose The purpose of this paper is to investigate the contrasting moderating effect of a firm’s exploration on the relationship between the two types of long-term incentives (stock options/stock ownership) for the chief executive officers and a firm’s long-term performance. Even though the two types of incentives are designed to improve long-term performance, the degrees of impact on long-term performance differ. Based on behavioral agency theory, this study theoretically and empirically examines the role of a firm’s exploration on the above relationship. Design/methodology/approach This study used three archival sources to obtain data on stock options, stock ownership, patents and exploration, financial measures, and others. Based on a sample of 1,963 firms in various industries from 1995 to 2006, this study tested the moderating effect of a firm’s exploration on the relationship between stock options/ownership and a firm’s performance. Findings This study reveals the contrasting moderating effect of a firm’s exploration on the relationship between stock options/ownership and a firm’s long-term performance: a positive moderating effect on the relationship between stock options and performance and a negative moderating effect on the relationship between stock ownership and performance. In addition, empirical evidence was added on the inverted U-shaped relationship between stock ownership and a firm’s long-term performance. Originality/value There is little research on a firm’s internal characteristics that strengthen or weaken the effects of stock options and stock ownership on firm performance. This study demonstrates the differential moderating effects of exploration on the relationship between stock options/stock ownership and long-term performance. Such effects of exploration come from the different risk features of stock options and stock ownership. The key implication is that stock options could be more effective than stock ownership to enhance a firm’s long-term performance when a firm has a strong exploration orientation.

scholarly journals Cannabis Use and Prospective Long-Term Association with Anxiety: A Systematic Review and Meta-Analysis of Longitudinal Studies: Usage du cannabis et association prospective à long terme avec l’anxiété: une revue systématique et une méta-analyse d’études longitudinales

2020 ◽  
pp. 070674372095225
Author(s):  
Siqi Xue ◽  
M. Ishrat Husain ◽  
Haoyu Zhao ◽  
Arun V. Ravindran
Keyword(s):  
Anxiety Disorder ◽  
Longitudinal Studies ◽  
Depressive Disorders ◽  
Meta Analysis ◽  
Cannabis Use ◽  
Hand Search ◽  
Published Evidence ◽  
Increased Risk ◽  
The Relationship

Objectives: Cannabis use is proposed as a risk factor for psychosis and is associated with depressive disorders. However, the relationship between recreational cannabis use and its longitudinal implications on anxiety conditions is less studied. The aim of this investigation is to systematically evaluate published literature and perform a meta-analysis of the data. Methods: A systematic search was performed of MEDLINE, Embase, and PsychINFO from inception to May 31, 2020, in addition to a hand search. Longitudinal studies that evaluated the relationship of cannabis use and development of anxiety were included. Where applicable, adjusted odds ratios ( ORs) were extracted, pooled, and evaluated using random-effects meta-analysis. Results: After screening of unique abstracts ( n = 6835), the final evaluation included 24 studies, of which 10 reported ORs that were analyzed quantitatively. Cannabis use was significantly associated with increased odds of developing any anxiety conditions ( OR = 1.25; 95% CI, 1.01 to 1.54). Cannabis use was not significantly associated with developing generalized anxiety disorder, panic disorder, or social anxiety disorder. Review of studies not reporting OR revealed mixed results but are suggestive of a link between cannabis use and increased rates/severity of anxiety. Conclusions: Published evidence suggests that cannabis use is likely associated with increased risk of anxiety in the long term but variability of study designs precludes declaration of a causal relationship. Awareness of this association is of relevance for both clinical practice and mental health policy implementation.

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