scholarly journals Iron deficiency, cognition, mental health and fatigue in women of childbearing age: a systematic review

2013 ◽  
Vol 2 ◽  
Author(s):  
Alecia J. Greig ◽  
Amanda J. Patterson ◽  
Clare E. Collins ◽  
Kerry A. Chalmers
Keyword(s):  
Mental Health ◽  
English Language ◽  
Negative Impact ◽  
Digit Span ◽  
Block Design ◽  
Cognitive Test ◽  
Fe Deficiency ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Meta Analyses

AbstractIt is known that Fe deficiency has a negative impact on cognitive function in children by altering brain energy metabolism and neurotransmitter function. It is unclear whether Fe deficiency has detrimental effects on cognition, mental health and fatigue in women of childbearing age. Our aim was to systematically review the literature to determine whether Fe deficiency in women of childbearing age affects cognition, mental health and fatigue, and whether a change in Fe status results in improvements in cognition, mental health and fatigue. Studies using Fe supplement interventions were reviewed to examine the effect of Fe deficiency in women of childbearing age (13–45 years) on their cognition, mental health and fatigue. English-language articles ranging from the earliest record to the year 2011 were sourced. The quality of retrieved articles was assessed and the Fe pathology, cognitive, mental health and fatigue data were extracted. Means and standard deviations from cognitive test data were included in meta-analyses of combined effects. Of the 1348 studies identified, ten were included in the review. Three studies showed poorer cognition and mental health scores and increased fatigue with Fe deficiency at baseline. Seven studies reported an improvement in cognitive test scores after Fe treatment. Results of three of these studies were included in meta-analyses of the effect of Fe supplement intervention on cognition. The results of the meta-analyses showed a significant improvement in Arithmetic scores after treatment (P < 0·01), but no effect on Digit Symbol, Digit Span or Block Design. While an improvement in cognition after Fe treatment was seen in seven out of ten studies, the evidence base is limited by poor study quality and heterogeneity across studies. Additional high-quality studies using consistent measures are warranted.

scholarly journals Iron nutrition in the UK: getting the balance right

2004 ◽  
Vol 63 (4) ◽  
pp. 519-528 ◽  
Author(s):  
Susan J. Fairweather-Tait
Keyword(s):  
Negative Impact ◽  
Iron Nutrition ◽  
Fe Deficiency ◽  
Adaptive Responses ◽  
Childbearing Age ◽  
Related Factors ◽  
High Fibre ◽  
Single Meal ◽  
Fe Homeostasis ◽  
The Uk

Fe homeostasis is considered in the context of the UK diet, using information on Fe intake and status from the National Diet and Nutrition Surveys. The importance of assessing Fe availability rather than total Fe intake is discussed. Dietary and host-related factors that determine Fe bioavailability (Fe utilised for Hb production) are reviewed using information from single-meal studies. When adaptive responses are taken into consideration, foods associated with higher Fe status include meat (haem-Fe and the ‘meat factor’) and fruits and fruit juice (vitamin C). Foods that may have a negative impact include dairy products (Ca), high-fibre foods (phytate) and tea and coffee (polyphenols), but the effects are more apparent in groups with marginal Fe deficiency, such as women of childbearing age. Analysis of dietary intake data on a meal-by-meal basis is needed to predict the influence of changing dietary patterns on Fe nutrition in the UK. Current information suggests that in the UK Fe deficiency is a greater problem than Fe overload.

scholarly journals An audit to review the extent to which appropriate preconception advice is given to women being discharged from mental health wards on psychotropic medication, in line with NICE guidelines

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S93-S94
Author(s):  
Helen Muskett ◽  
Kirsty Bradley ◽  
Lauren Stott ◽  
William Moreton ◽  
Sarah Jones
Keyword(s):  
Mental Health ◽  
Psychotropic Medication ◽  
Action Plan ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Nice Guideline ◽  
Word Search ◽  
Future Pregnancy ◽  
Preconception Counselling ◽  
The Impact

AimsThe release of the Cumberlege Report in 2020 served as a reminder of the importance of informed consent for women when they are started on treatment that may affect their fertility or future pregnancies.Our aim was to evaluate current performance with regards to advice given to women of childbearing age around contraception, impacts of psychotropic medication on fertility and future pregnancies, and availability of preconception counselling.MethodStandard identified as NICE Guideline 192 (Antenatal and Postnatal Mental Health), sections 1.2 and 1.4.60 female inpatients were selected by looking at the most recent discharges prior to 03/11/2020 from 3 local acute adult wards. All females aged between 18 and 48 years were included.Electronic notes were reviewed for each patient. The discharge summary and last four ward round entries were reviewed, then key-word search of the patients’ records was performed using the terms “pregnan*”, “conception”, “contraception”, and “fertility”.The following information for each patient was documented in a spreadsheet:Discharge medicationIs there any discussion or advice around contraception?Have women taking antipsychotic medication been given advice regarding the possible impact on fertility?Has the potential impact of psychotropic medication on a future pregnancy been discussed?Has advice been given about the availability of preconception counselling should they plan a pregnancy in future?ResultOn discharge, a total of 33 women were taking one or more antipsychotics and 14 were prescribed a benzodiazepine. 24 women were discharged with antidepressants and 10 women were using a mood stabilising agent. 8 women were discharged without any psychotropic medication.Overall, 4 women received advice about contraception, and a further 8 women were already using contraception. The impact of taking an antipsychotic on fertility was not discussed with any patient. No women were advised about pre-conception counselling. The impact of taking psychotropic medication on a future pregnancy was discussed with one woman.ConclusionCurrent practice falls well below the standard set by NICE. Opportunities to inform women are being missed, and this has implications for the wellbeing of the patient and, potentially, future children.Action plan;Present findings at teaching.Deliver local teaching covering preconception counselling and the role of adult mental health teams when managing women of childbearing age.Produce a poster for inpatients wards and an information leaflet for women of childbearing age to aid with discussions.Create a poster for doctors’ offices to remind about NICE standards and documentation.Re-audit in 6 months.

scholarly journals The responses of serum transferrin receptors to iron supplements in subjects with iron-deficiency erythropoiesis and iron-deficiency anaemia

2008 ◽  
Vol 99 (2) ◽  
pp. 416-420 ◽  
Author(s):  
Xiao-Ming Lin ◽  
Wei Tian ◽  
Le Ma ◽  
Zhu Long ◽  
Juan Zhang ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Fe Deficiency ◽  
Serum Transferrin ◽  
Transferrin Receptors ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Iron Supplements ◽  
Deficiency Anaemia ◽  
Biochemical Indices

We aimed to study the response of serum transferrin receptors (sTfR) to Fe supplementation in women of childbearing age with Fe-deficiency erythropoiesis (IDE) and Fe-deficiency anaemia (IDA). Primary screening was performed in 942 women ranging in age from 18 to 45 years. After Fe-related biochemical indices such as serum ferritin, Zn protoporphyrin and Hb were determined, the subjects were divided into four groups: normal, Fe store depletion, IDE and IDA. A total of 131 women were randomly selected from the normal, IDE and IDA groups. Subsequently, seventy-six women with IDE and IDA were given various doses of Fe (14 mg/d for IDE; 28 mg/d for IDA) with ferrousl-threonate capsules for twelve consecutive weeks. After receiving Fe supplements, the levels of Fe and sTfR were determined at weeks 0, 3, 6, 9 and 12.The levels of sTfR in women of childbearing age with IDE and IDA were significantly higher than those in the normal group. After receiving Fe supplements, the levels of sTfR were significantly decreased in women of childbearing age with IDE and IDA, while the levels of serum ferritin were significantly increased. In conclusion, STfR can be used as a reliable indicator for assessing the efficacy of Fe supplements.

scholarly journals Pathogens, Virulence and Resistance Genes Surveillance with Metagenomics Can Pre-empt Dissemination and Escalation of Untreatable Infections: A Systematic Review and Meta-analyses.

2021 ◽  
Author(s):  
John Osei Sekyere ◽  
Sara Lino Faife
Keyword(s):  
Resistance Genes ◽  
Pathogenic Bacteria ◽  
English Language ◽  
Negative Impact ◽  
Tap Water ◽  
Chi Square ◽  
Genetic Elements ◽  
Integrative And Conjugative Elements ◽  
Antimicrobial Resistance Genes ◽  
Meta Analyses

Background: The dissemination of pathogens carrying genetic elements such as antimicrobial resistance genes (ARGs), mobile-genetic elements (MGEs), virulome and methylome have a negative impact on food and environment safety, water quality and animal and human health. The applications of metagenomics to monitor and identify the prevalence/endemicity and emergence of these pathogenic agents from different sources were examined. Methods: Articles published in English language up to October 2020 were searched for on PubMed. Qualitative and quantitative data extracted from the included articles were translated into charts and maps. GraphPad Prism 9.0.2 was used to undertake statistical analysis using descriptive and column statistics, Chi-square, ANOVA, Wilcoxons signed-rank, and one-sample t-test. Results: In all, 143 articles from 39 countries from Europe, America, Asia, and Africa were quantitatively analysed. Metagenomes from sewage/wastewater, surface water samples (ocean, sea, river lake, stream and tap water), WWTP, effluents and sludge samples contained pathogenic bacteria (Aeromonas, Acinetobacter, Pseudomonas, Streptococcus, Bacteroides, Escherichia coli, Salmonella enterica, Klebsiella pneumoniae and Acinetobacter baumannii), viruses (Adenovirus, Enterovirus, Hepatovirus, Mamastrovirus and Rotavirus) and parasites (Acanthamoeba, Giardia, Entamoeba, Blastocystis and Naegleria). Integrons, plasmids, transposons, insertion sequences, prophages and integrative and conjugative elements were identified. ARGs mediating resistance to important antibiotics, including β-lactams, aminoglycosides, fluoroquinolones, and tetracycline, and virulence factors such as secretion system, adherence, antiphagocytosis, capsule, invasion, iron uptake, hemolysin, and flagella. Conclusion: Clinically important pathogens, ARGs, and MGEs were identified in diverse clinical, environmental, and animal sources through metagenomics, which can be used to determine the prevalence and emergence of known and unknown pathogens and ARGs.

scholarly journals THYROID DYSFUNCTION IN WOMEN OF REPRODUCTIVE AGE WHO PARTICIPATED IN HOSTILITIES AND SUFFERED CONTUSIONS

2020 ◽  
Author(s):  
Kaminskiy Viacheslav Volodymyrovych ◽  
Suslikova Lidiya Viktorivna ◽  
Serbeniuk Anastasia Valeriivna ◽  
Dercach Andriy Dmytrovych
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Reproductive Health ◽  
Thyroid Dysfunction ◽  
Reproductive Age ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Women Of Reproductive Age ◽  
Improve Treatment

The article presents data on the prevalence of thyroid hormonal disorders and the establishment of their relationship between the state of mental health and the functional state of body systems in women who participated in hostilities who suffered contusions. We aimed to assessing the prevalence and effectiveness of the diagnosis of thyroid dysfunction in women of childbearing age with impaired reproductive health who participated in hostilities and suffered contusions, to improve treatment and rehabilitation measures and quality of life of these women.

Physical and Psychological Benefits of Written Emotional Expression

2015 ◽  
Vol 20 (4) ◽  
pp. 242-251 ◽  
Author(s):  
Éva Kállay
Keyword(s):  
Mental Health ◽  
Expressive Writing ◽  
Mental Health Problems ◽  
Cost Effective ◽  
Health Problems ◽  
Future Research ◽  
Psychological Benefits ◽  
Cost Effective Treatment ◽  
Meta Analyses

Abstract. The last several decades have witnessed a substantial increase in the number of individuals suffering from both diagnosable and subsyndromal mental health problems. Consequently, the development of cost-effective treatment methods, accessible to large populations suffering from different forms of mental health problems, became imperative. A very promising intervention is the method of expressive writing (EW), which may be used in both clinically diagnosable cases and subthreshold symptomatology. This method, in which people express their feelings and thoughts related to stressful situations in writing, has been found to improve participants’ long-term psychological, physiological, behavioral, and social functioning. Based on a thorough analysis and synthesis of the published literature (also including most recent meta-analyses), the present paper presents the expressive writing method, its short- and long-term, intra-and interpersonal effects, different situations and conditions in which it has been proven to be effective, the most important mechanisms implied in the process of recovery, advantages, disadvantages, and possible pitfalls of the method, as well as variants of the original technique and future research directions.

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