Evidence for the treatment of moderate depression: a systematic review

2017 ◽  
Vol 34 (3) ◽  
pp. 197-204 ◽  
Author(s):  
D. Aherne ◽  
A. Fitzgerald ◽  
C. Aherne ◽  
N. Fitzgerald ◽  
M. Slattery ◽  
...  
Keyword(s):  
Systematic Review ◽  
Depressive Disorders ◽  
Controlled Trial ◽  
Combined Treatment ◽  
Antidepressant Medication ◽  
Inclusion Criteria ◽  
Randomized Controlled ◽  
Search Terms ◽  
Moderate Depression ◽  
Different Levels

ObjectivesThis study aims to investigate existing evidence for the effectiveness of psychological treatments and/or antidepressant medication as a treatment for those diagnosed with moderate levels of depression.MethodsA PRISMA systematic review of articles using electronic research databases (2000–2014) was conducted to identify studies investigating the effectiveness of psychotherapy and/or medication as a treatment for people with moderate levels of depression. Search terms included moderate depression, psychotherapy and/or medication, depressive disorders, antidepressants, psychotherapy, mental health services, and randomized-controlled trial (RCT). The included studies were then assessed, extracted, and synthesised.ResultsA total of 14 studies met the inclusion criteria (11 RCTs and three additional studies) for this review. The findings of the systematic review indicate that there is limited evidence available specific to the treatment of moderate depression and that this research seems to suggest that psychotherapy or combined treatment has a beneficial effect.ConclusionsGiven that depression is one of the biggest challenges the world faces at present, further research is required to examine the effectiveness of treatment for different levels of depression severity.

scholarly journals Depression and anxiety in individuals with amyotrophic lateral sclerosis: a systematic review

2016 ◽  
Vol 38 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Tatiana Lins Carvalho ◽  
Lilian Maria Sanguinett de Almeida ◽  
Camila Maria Araújo Lorega ◽  
Mirella Francyne Oliveira Barata ◽  
Maria Lúcia Brito Ferreira ◽  
...  
Keyword(s):  
Systematic Review ◽  
Amyotrophic Lateral Sclerosis ◽  
Depressive Disorders ◽  
Depression And Anxiety ◽  
Inclusion Criteria ◽  
Eligibility Criteria ◽  
Symptoms Of Depression ◽  
Two Stages ◽  
Different Levels ◽  
Lateral Sclerosis

Introduction Studies assessing symptoms of depression and anxiety in individuals with amyotrophic lateral sclerosis (ALS) have reported contradictory results. The objective of this systematic review is to identify the prevalence of these mood disorders in the literature. Methods We searched the PubMed, HighWire, MEDLINE, SciELO, LILACS and ScienceDirect databases. Literature was selected for review in two stages, according to eligibility criteria. The first stage involved searching databases and checking titles and abstracts. The second step consisted of reading complete articles and excluding those that did not meet the inclusion criteria. The inclusion criteria were articles written in Portuguese, English or Spanish, published in the last five years and involving people with ALS diagnosed according to the El Escorial criteria. Results The database searches returned a total of 1,135 titles and abstracts and then 1,117 of these were excluded. Eighteen articles were selected for review. The 12-item Amyotrophic Lateral Sclerosis Depression Inventory (ADI-12) was the only instrument designed specifically to assess depression in ALS, but it was only used in three studies. No instruments specifically designed for anxiety in ALS were used. A large number of studies found presence and slight increase of anxiety disorders. There was considerable large variation in the results related to depressive disorders, ranging from moderate depression to an absence of symptoms. Conclusions Patients with ALS may exhibit symptoms of depression and anxiety at different levels, but there is a need for studies using specific instruments with larger samples in order to ascertain the prevalence of symptoms in ALS and the factors associated with it.

scholarly journals The effects of Rhodiola Rosea supplementation on depression, anxiety and mood – A Systematic Review

2020 ◽  
Vol 3 (1) ◽  
pp. 72-82
Author(s):  
Fanaras Konstantinos ◽  
Reinhard Heun
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Rhodiola Rosea ◽  
Depression Symptoms ◽  
Controlled Trials ◽  
Inclusion Criteria ◽  
Randomized Controlled ◽  
Moderate Depression ◽  
Literature Searches ◽  
Made In

AbstractObjectivesRhodiola rosea is an adaptogen herb from the Crassulaceae family, which has been vastly used in the Russian and Chinese medicine. The herb is used against depression, anxiety, mental and physical fatigue and to promote overall health. In this systematic review, we examined the effects of R. rosea on depression, anxiety and mood, as these are the most relevant to mental health.MethodsLiterature searches were made in PubMed using the term ‘Rhodiola rosea’. Inclusion criteria were: Randomized controlled trials using interventions of R. rosea on any type of participants, while focusing on the effects of the intervention on depression, anxiety or mood. Mixed interventions of R. rosea with other herbs were excluded. Studies not published in English or Greek were excluded.ResultsA total of 39 randomized controlled trials were identified and their abstract was screened. After screening, a total of 17 papers were excluded because they were focusing on irrelevant outcomes. The full text of the remaining 22 papers was read and an additional 17 papers were excluded. These papers were excluded because they were eventually not focusing on our main outcome or they were using R. rosea interventions with other herbs. In the end, a total of 5 papers (n = 327 participants) were found eligible for our systematic review. In these studies, R. rosea seems to improve the symptoms of mild to moderate depression, symptoms of mild anxiety and to enhance mood. The last date of our search was October 13, 2019.ConclusionRhodiola rosea supplementation may alleviate symptoms of mild to moderate depression and mild anxiety, while it may also enhance mood. The findings of our review are not definite due to the lack of available experimental data. Randomized controlled trials with a low risk of bias are needed to further study the herb.

scholarly journals Effects of manual therapy techniques in the treatment of pain in post mastectomy patients: systematic review.

2014 ◽  
Vol 12 ◽  
pp. 190
Author(s):  
Franciane Batista Basilio ◽  
Raphaela Medeiros Miranda Anjos ◽  
Elany Pereira Medeiros ◽  
Elaine Marques Franco Melo ◽  
Rodrigo Marcel Valentim Silva
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trial ◽  
Manual Therapy ◽  
Muscle Pain ◽  
Controlled Trial ◽  
Inclusion Criteria ◽  
Functional Changes ◽  
Randomized Controlled ◽  
Treatment Objective ◽  
External Causes

Introduction: Cancer is now the third leading cause of death in the world, surpassed only by accidents and cardiovascular deaths by external causes, among them stands mammary carcinoma. Mastectomy is in a procedure consisting of invasive breast removal due to some anatomical and functional changes previously diagnosed. With the growth of the disease and its high content in increasingly young women, Manual Therapy has been used as a new form of treatment. Objective: To show the effects of manual therapy in patients after mastectomy surgery. Method: This was a systematic review study in which secondary and tertiary sources were used, using the databases PubMed, Medline, Lilacs and SciELO. It was adopted as inclusion criteria studies classified as: a randomized controlled trial, with publication period between 2009 and 2013. Were used as search terms: "Mastectomy", "Neck", "Shoulder Pain", "Musculoskeletal Manipulations" and "Functionality". Results: Among the 37 initially selected by electronic search in the databases of articles, 25 were excluded for the title did not meet the inclusion criteria. Of the 12 retained studies, 5 were excluded for duplicity. 7 studies were selected for a more thorough analysis through summary, 2 of them being excluded. The remaining 5 articles were evaluated from reading the text. It can be seen that the manual therapy techniques have significant results in the alleviation of muscle pain in patients submitted to surgery mastectomia. Conclusion: It can be seen that the manual therapy techniques have significant results in the alleviation of muscle pain in patients undergoing the mastectomy surgery. However, there is still a lack of studies of type randomized controlled trial on the effects of manual therapy in patients in the postoperative period of mastectomy

Comparison of three methods for the management of fragmented medial coronoid process in the dog

2008 ◽  
Vol 21 (02) ◽  
pp. 106-109 ◽  
Author(s):  
W. J. Gordon-Evans ◽  
M. G. Conzemius ◽  
R. B. Evans
Keyword(s):  
Systematic Review ◽  
Medical Management ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Surgical Techniques ◽  
Objective Measure ◽  
Coronoid Process ◽  
Clinical Question ◽  
Inclusion Criteria ◽  
Randomized Controlled

SummaryThe objective of this review and analysis was to compare arthroscopy, medial arthrotomy and medical management for treating fragmented coronoid process in the dog. The data come from manuscripts published in peer-reviewed veterinary journals, and the study design is a systematic review followed by meta-analysis. The meta-analysis combines data from a set of studies so that surgical techniques and medial management can be compared in a single analysis. Several literature databases and veterinary texts were thoroughly searched to provide a list of over 400 candidate manuscripts. Inclusion criteria were used to filter the candidate manuscripts to a final set of fourmanuscripts that directly pertained to the clinical question. They were scored for their evidentiary value using a semi-objective measure. The results were that arthroscopy was superior to medial arthrotomy and medical management, but medial arthrotomy was not superior to medical management. Only one manuscript was a randomized controlled trial, hence the results must be tempered by the evidentiary value of the data.

scholarly journals The The Effectiveness of Early Mobilization Time on Balance and Functional Ability after Ischemic Stroke

2019 ◽  
Vol 7 (7) ◽  
pp. 1088-1092
Author(s):  
Umi Budi Rahayu ◽  
Samekto Wibowo ◽  
Ismail Setyopranoto
Keyword(s):  
Randomized Controlled Trial ◽  
Ischemic Stroke ◽  
Functional Ability ◽  
Controlled Trial ◽  
Early Mobilization ◽  
Berg Balance Scale ◽  
Early Mobilisation ◽  
Inclusion Criteria ◽  
Randomized Controlled ◽  
Significant Difference

BACKGROUND: Early mobilisation (EM) after-ischemic stroke is a motor learning intervention aimed to restore nerve cells and to improve balance and functional ability. Unfortunately, the study of when this intervention began has not been widely studied. AIM: On this study was compared the effect of EM started at 24 hours and 48 hours after an ischemic stroke on balance and functional ability. MATERIAL AND METHODS: Randomized controlled trial involving 40 patients on 2 groups meeting predefined inclusion criteria. The levels of balance were measured using the Berg Balance Scale, and the functional ability was measured using the Barthel Index, at 5th and 7th day. RESULTS: A significant difference was observed in both balance (p = 0.038) and functional ability (p = 0.021) obtained on the 7th day of assessment between both groups. A significant difference on the 5th day was observed only in the functional ability (p = 0.002) and not in the balance (p = 0.147), between the groups. CONCLUSION: EM started at 24 hours after the ischemic stroke has been found to have a better impact on balance and functional ability compared to that at 48 hours.

scholarly journals Manual Therapy in Cervical and Lumbar Radiculopathy: A Systematic Review of the Literature

2021 ◽  
Vol 18 (11) ◽  
pp. 6176
Author(s):  
Tomasz Kuligowski ◽  
Anna Skrzek ◽  
Błażej Cieślik
Keyword(s):  
Manual Therapy ◽  
Functional Outcomes ◽  
Web Of Science ◽  
Current Knowledge ◽  
Controlled Trial ◽  
Future Research ◽  
Lumbar Radiculopathy ◽  
Inclusion Criteria ◽  
Randomized Controlled ◽  
The Mean

The aim of this study was to describe and update current knowledge of manual therapy accuracy in treating cervical and lumbar radiculopathy, to identify the limitations in current studies, and to suggest areas for future research. The study was conducted according to PRISMA guidelines for systematic reviews. A comprehensive literature review was conducted using PubMed and Web of Science databases up to April 2020. The following inclusion criteria were used: (1) presence of radiculopathy; (2) treatment defined as manual therapy (i.e., traction, manipulation, mobilization); and (3) publication defined as a Randomized Controlled Trial. The electronic literature search resulted in 473 potentially relevant articles. Finally, 27 articles were accepted: 21 on cervical (CR) and 6 in lumbar radiculopathy (LR). The mean PEDro score for CR was 6.6 (SD 1.3), and for LR 6.7 (SD 1.6). Traction-oriented techniques are the most frequently chosen treatment form for CR and are efficient in reducing pain and improving functional outcomes. In LR, each of the included publications used a different form of manual therapy, which makes it challenging to summarize knowledge in this group. Of included publications, 93% were either of moderate or low quality, which indicates that quality improvement is necessary for this type of research.

Analysis of Gabapentin’s Efficacy in Tinnitus Treatment: A Systematic Review

2021 ◽  
pp. 000348942110189
Author(s):  
Matheus Pedrosa Tavares ◽  
Fayez Bahmad
Keyword(s):  
Systematic Review ◽  
Controlled Trial ◽  
Critical Evaluation ◽  
Outcome Study ◽  
Qualitative Synthesis ◽  
Eligibility Criteria ◽  
Double Blind ◽  
Randomized Controlled ◽  
Study Selection ◽  
Tinnitus Treatment

Objectives: Tinnitus can be a chronic symptom that brings disability and distress. Some studies suggested that gabapentin might be effective on tinnitus relief. The objective of the study is to perform a systematic review in order to evaluate the efficacy of oral gabapentin in patients with tinnitus. Methods: A literature search was conducted in English and following the recommendations from PRISMA. The terms used were: (“tinnitus” OR “subjective tinnitus”) AND (“gabapentin”). The study selection was performed following the eligibility criteria in accordance to the PICOS (population, intervention, comparison, outcome, study design) strategy—patients with tinnitus; oral gabapentin; placebo; reduction of tinnitus severity questionnaires scores; prospective, double-blind, randomized controlled trial, respectively. The selected studies were included in qualitative synthesis. The studies were analyzed according to Joanna Briggs Institute’s critical appraisal checklist for randomized controlled trials. Results: One hundred twenty-one studies were found in 9 databases and 8 studies were found in gray literature. After study selection, 6 articles were read in full. Then, 2 studies were excluded and 4 were included in qualitative synthesis. All 4 articles were analyzed according to critical evaluation checklist. Conclusions: There is insufficient evidence to recommend the use of gabapentin for patients with tinnitus.

Sign in / Sign up

Export Citation Format

Share Document