scholarly journals Low seroprevalence of SARS-CoV-2 infection among healthcare workers of the largest children hospital in Milan during the pandemic wave

2020 ◽  
Vol 41 (12) ◽  
pp. 1468-1469 ◽  
Author(s):  
Antonella Amendola ◽  
Elisabetta Tanzi ◽  
Laura Folgori ◽  
Lucia Barcellini ◽  
Silvia Bianchi ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Pandemic Wave

scholarly journals High Rates of SARS-CoV-2 Family Transmission in Children of Healthcare Workers During the First Pandemic Wave in Madrid, Spain

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ana Méndez-Echevarría ◽  
Talía Sainz ◽  
Beatriz de Felipe ◽  
Sonia Alcolea ◽  
Peter Olbrich ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Pandemic Wave ◽  
Family Transmission

scholarly journals Barriers to severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing reported by healthcare workers during the first pandemic wave at an academic center in Boston, Massachusetts

2021 ◽  
pp. 1-4
Author(s):  
Julia Zubiago ◽  
Alysse G. Wurcel ◽  
Rubeen Guardado ◽  
Elena Byhoff
Keyword(s):  
Healthcare Workers ◽  
Perceived Barriers ◽  
Academic Center ◽  
Employment Factors ◽  
Respiratory Coronavirus ◽  
To Receive ◽  
Pandemic Wave ◽  
Boston Hospital

Abstract Healthcare workers (HCWs) experience barriers to severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing specific to their perceptions of access, and employment factors. A survey was sent to all employees at one Boston hospital to examine their perceived barriers to testing. HCWs who reported difficulty paying their bills were less likely to receive a SARS-CoV-2 test.

scholarly journals Reconstructing transmission chains of SARS-CoV-2 amid multiple outbreaks in a geriatric acute-care hospital

2022 ◽  
Author(s):  
Mohamed Abbas ◽  
Anne Cori ◽  
Samuel Cordey ◽  
Florian Laubscher ◽  
Tomás Robalo Nunes ◽  
...  
Keyword(s):  
Acute Care ◽  
Healthcare Workers ◽  
Acute Care Hospital ◽  
Credible Interval ◽  
Care Hospital ◽  
Sequencing Data ◽  
Genetic Sequencing ◽  
Modelling Framework ◽  
Pandemic Wave ◽  
Geriatric Settings

Background There is ongoing uncertainty regarding transmission chains and the respective roles of healthcare workers (HCWs) and elderly patients in nosocomial outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) in geriatric settings. Methods We performed a retrospective cohort study including patients with nosocomial coronavirus disease 2019 (COVID–19) in four outbreak–affected wards, and all SARS–CoV–2 RT–PCR positive HCWs from a Swiss university–affiliated geriatric acute–care hospital that admitted both Covid–19 and non–Covid–19 patients during the first pandemic wave in Spring 2020. We combined epidemiological and genetic sequencing data using a Bayesian modelling framework, and reconstructed transmission dynamics of SARS–CoV–2 involving patients and HCWs, in order to determine who infected whom. We evaluated general transmission patterns according to type of case (HCWs working in dedicated Covid–19 cohorting wards: HCWcovid; HCWs working in non–Covid–19 wards where outbreaks occurred: HCWoutbreak; patients with nosocomial Covid–19: patientnoso) by deriving the proportion of infections attributed to each type of case across all posterior trees and comparing them to random expectations. Results During the study period (March 1 to May 7, 2020) we included 180 SARS–CoV–2 positive cases: 127 HCWs (91 HCWcovid, 36 HCWoutbreak) and 53 patients. The attack rates ranged from 10–19% for patients, and 21% for HCWs. We estimated that there were 16 importation events (3 patients, 13 HCWs) that jointly led to 16 secondary cases. Most patient–to–patient transmission events involved patients having shared a ward (97.6%, 95% credible interval [CrI] 90.4–100%), in contrast to those having shared a room (44.4%, 95%CrI 27.8–62.5%). Transmission events tended to cluster by type of case: patientnoso were almost twice as likely to be infected by other patientnoso than expected (observed:expected ratio 1.91, 95%CrI 1.08 – 4.00, p = 0.02); similarly, HCWoutbreak were more than twice as likely to be infected by other HCWoutbreak than expected (2.25, 95%CrI 1.00–8.00, p = 0.04). The proportion of infectors of HCWcovid were as expected as random. The proportions of high transmitters (≥2 secondary cases) were significantly higher among HCWoutbreak than patientnoso in the late phases (26.2% vs. 13.4%, p<2.2e–16) of the outbreak. Conclusions Most importation events were linked to HCW. Unexpectedly, transmission between HCWcovid was more limited than transmission between patients and HCWoutbreak. This highlights gaps in infection control and suggests possible areas of improvements to limit the extent of nosocomial transmission.

scholarly journals Intention to get vaccinations against COVID-19 in French healthcare workers during the first pandemic wave: a cross-sectional survey

2021 ◽  
Vol 108 ◽  
pp. 168-173 ◽  
Author(s):  
A. Gagneux-Brunon ◽  
M. Detoc ◽  
S. Bruel ◽  
B. Tardy ◽  
O. Rozaire ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Pandemic Wave

scholarly journals Low seropositivity for SARS-CoV-2 antibodies among healthcare workers after the first COVID-19 pandemic wave in Greece

Public Health ◽  
2021 ◽  
Author(s):  
P. Galanis ◽  
D. Kaitelidou ◽  
P. Prezerakos ◽  
I. Kotsiopoulos ◽  
O. Siskou ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Pandemic Wave

scholarly journals COVID-19 in patients hospitalized and healthcare workers: what have changed after the first wave in a university hospital

2021 ◽  
Author(s):  
Luiz Vinicius Leao Moreira ◽  
Gabriela Barbosa ◽  
Luciano Kleber de Souza Luna ◽  
Alberto Fernando Oliveira Justo ◽  
Ana Paula Cunha Chaves ◽  
...  
Keyword(s):  
Viral Load ◽  
Healthcare Workers ◽  
Sao Paulo ◽  
Hospitalized Patients ◽  
University Hospital ◽  
São Paulo ◽  
The Mean ◽  
Wave Methods ◽  
The Impact ◽  
Pandemic Wave

Objective: To assess the COVID-19 frequency rates in hospitalized patients (HP) and healthcare workers (HCW), viral load inference, and the impact of vaccination and variants of concern (VOC) during the first pandemic wave. Methods: We evaluated the COVID-19 diagnostics at Hospital Sao Paulo, Brazil, from March 2020 to April 2021, in 10,202 samples (6,502 HP and 3,700 HCW) tested by RT-qPCR, inferring viral load by cycle threshold (Ct) values, and frequency rates. Results: SARS-CoV-2 was detected in 31.27% of individuals (32.23% HP and 29.80% HCW). The mean age of HP positives was 57.26 +/- 18.29 years (median = 59), with a mean Ct value of 25.55 +/- 6.07. Neither age nor Ct values in both groups have significantly differed during the first and second waves or even since the predominance of VOC P.1 on March 2021. Conclusions: The COVID-19 epidemic curves of HP and HCW accompanied the variations reported in Sao Paulo city, as well as the variation of hospitalization and occupancy of ICU beds. The VOC P.1 has no impact on the viral load, since its predominance in March 2021. The vaccination of HCW may have contributed to a decrease in the positivity rates, although more studies will provide a better understanding of the impact of immunization on the COVID-19 pandemic.

scholarly journals Seroprevalence of SARS-CoV-2 IgG specific antibodies among healthcare workers in the Northern Metropolitan Area of Barcelona, Spain, after the first pandemic wave

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0244348
Author(s):  
Jaume Barallat ◽  
Gema Fernández-Rivas ◽  
Bibiana Quirant-Sánchez ◽  
Victoria González ◽  
Maria Doladé ◽  
...  
Keyword(s):  
Metropolitan Area ◽  
Healthcare Workers ◽  
Limit Of Detection ◽  
Health Care Systems ◽  
Geographical Area ◽  
Risk Groups ◽  
Serum Samples ◽  
The North ◽  
Healthcare Needs ◽  
Pandemic Wave

Background The rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) around the world has caused a global pandemic, infecting millions of individuals, with an unprecedented impact in health care systems worldwide. Healthcare workers are one of the risk groups that need to be well protected, due to their strategic role in patient management, presently and in prevention of healthcare needs for future outbreaks. Here, we present the results of the first SARS-CoV-2 seroprevalence study in the Northern Metropolitan Area of Barcelona, Spain. Methods IgG SARS-CoV-2 antibodies were analyzed in serum samples from 7563 healthcare workers of the Northern Metropolitan Area of Barcelona. Samples were collected after the first pandemic wave (from May 4th to May 22nd, 2020) and were analyzed by automated chemiluminescence assays. All samples were tested for IgG anti-S1/S2. Participant samples with negative or equivocal results but with analytical signals above the limit of detection and/or previously confirmed COVID-19 diagnosis were also tested for IgG anti-Nucleocapsid. Results A total of 779 of 7563 (10.3%) healthcare workers were positive for anti-SARS-CoV-2 IgG (specific for either S1/S2 or N antigens). No significant differences were observed between those working at primary care or at the reference hospital. Interestingly, among 341 participants with a confirmed COVID-19 diagnosis, 36 (10.55%) tested negative for SARS-CoV-2 IgG (both S1/S2 and recombinant N antigen). Conclusion Seroprevalence of anti-SARS-CoV-2 IgG in the healthcare workers of the North Metropolitan Area of Barcelona was higher than in the general population in the same geographical area. Safety measures have to be stressed in order to protect these essential workers from future pandemic waves.

scholarly journals SARS-CoV-2 nosocomial infection acquired in a French university hospital during the 1st wave of the Covid-19 pandemic, a prospective study

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
A. Landoas ◽  
F. Cazzorla ◽  
M. Gallouche ◽  
S. Larrat ◽  
B. Nemoz ◽  
...  
Keyword(s):  
Hand Hygiene ◽  
Healthcare Workers ◽  
Prospective Observational Study ◽  
University Hospital ◽  
Healthcare Facilities ◽  
Hospitalised Patients ◽  
Hygiene Measures ◽  
Hygiene Compliance ◽  
A Prospective Study ◽  
Pandemic Wave

Abstract Background In healthcare facilities, nosocomial transmissions of respiratory viruses are a major issue. SARS-CoV-2 is not exempt from nosocomial transmission. Our goals were to describe COVID-19 nosocomial cases during the first pandemic wave among patients in a French university hospital and compliance with hygiene measures. Methods We conducted a prospective observational study in Grenoble Alpes University Hospital from 01/03/2020 to 11/05/2020. We included all hospitalised patients with a documented SARS-CoV-2 diagnosis. Nosocomial case was defined by a delay of 5 days between hospitalisation and first symptoms. Hygiene measures were evaluated between 11/05/2020 and 22/05/2020. Lockdown measures were effective in France on 17/03/2020 and ended on 11/05/2020. Systematic wearing of mask was mandatory for all healthcare workers (HCW) and visits were prohibited in our institution from 13/03/2021 and for the duration of the lockdown period. Results Among 259 patients included, 14 (5.4%) were considered as nosocomial COVID-19. Median time before symptom onset was 25 days (interquartile range: 12–42). Eleven patients (79%) had risk factors for severe COVID-19. Five died (36%) including 4 deaths attributable to COVID-19. Two clusters were identified. The first cluster had 5 cases including 3 nosocomial acquisitions and no tested HCWs were positive. The second cluster had 3 cases including 2 nosocomial cases and 4 HCWs were positive. Surgical mask wearing and hand hygiene compliance were adequate for 95% and 61% of HCWs, respectively. Conclusions The number of nosocomial COVID-19 cases in our hospital was low. Compliance regarding mask wearing, hand hygiene and lockdown measures drastically reduced transmission of the virus. Monitoring of nosocomial COVID-19 cases during the first wave enabled us to determine to what extent the hygiene measures taken were effective and patients protected. Trial registration Study ethics approval was obtained retrospectively on 30 September 2020 (CECIC Rhône-Alpes-Auvergne, Clermont-Ferrand, IRB 5891).

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