Changes in vascular accesses and in incidence rates of dialysis-related bloodstream infections in Québec, Canada, 2011–2017

2019 ◽  
Vol 40 (6) ◽  
pp. 627-631
Author(s):  
Élise Fortin ◽  
Manale Ouakki ◽  
Claude Tremblay ◽  
Jasmin Villeneuve ◽  
Simon Desmeules ◽  
...  
Keyword(s):  
Cohort Study ◽  
Incidence Rate ◽  
Poisson Regression ◽  
Generalized Estimating Equations ◽  
Bloodstream Infections ◽  
Incidence Rates ◽  
Chronic Dialysis ◽  
Individual Level ◽  
The Individual ◽  
Over Time

AbstractObjective:Surveillance of dialysis-related bloodstream infections (DRBSIs) has been mandatory in Québec since April 2011. The aim of this study was to describe the epidemiology of DRBSIs in Québec.Methods:Cohort study of prevalent patients undergoing chronic dialysis in the 36 facilities that participated without interruption in the provincial surveillance, between April 2011 and March 2017. Two indicators were analyzed: proportion of patient months dialyzed using a fistula (a patient month is a 28-day cycle during which an individual patient received dialysis) and incidence rate of DRBSI. Binomial and Poisson regression with generalized estimating equations were used to describe the evolution of indicators over time and to quantify the association between facilities’ proportion of fistulas and their incidence rate.Results:Globally, 42.6% of all patient months were dialyzed using a fistula, but there was a statistically significant decrease over time (46.2% in 2011–2012 to 39.3% in 2016–2017). Despite this decline in the use of fistulas, rates of DRBSIs have also decreased, going from 0.38 DRBSIs per 100 patient months in 2011–2012 to 0.23 DRBSIs per 100 patient months in 2016–2017. No association was found between facility use of fistulas and the rate of DRBSI. At the individual level, however, the DRBSI rate was 4.12 times higher for patients using a catheter.Conclusions:In Québec, the rate of DRBSIs has decreased over a 6-year period despite an increasing proportion of patients dialyzed by catheter.

scholarly journals Geographical variation and clustering are found in atrial fibrillation beyond socioeconomic differences: a Danish cohort study, 1987–2015

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Kirstine Wodschow ◽  
Kristine Bihrmann ◽  
Mogens Lytken Larsen ◽  
Gunnar Gislason ◽  
Annette Kjær Ersbøll
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Cohort Study ◽  
Incidence Rate ◽  
Socioeconomic Position ◽  
Geographical Variation ◽  
Incidence Rates ◽  
Socioeconomic Differences ◽  
Individual Level ◽  
Geographical Variations

Abstract Background The prevalence and incidence rate of atrial fibrillation (AF) increase worldwide and AF is a risk factor for more adverse cardiovascular diseases including stroke. Approximately 44% of AF cases cannot be explained by common individual risk factors and risk might therefore also be related to the environment. By studying geographical variation and clustering in risk of incident AF adjusted for socioeconomic position at an individual level, potential neighbourhood risk factors could be revealed. Methods Initially, yearly AF incidence rates 1987–2015 were estimated overall and stratified by income in a register-based cohort study. To examine geographical variation and clustering in AF, we used both spatial scan statistics and a hierarchical Bayesian Poisson regression analysis of AF incidence rates with random effect of municipalities (n = 98) in Denmark in 2011–2015. Results The 1987–2015 cohort included 5,453,639 individuals whereof 369,800 were diagnosed with an incident AF. AF incidence rate increased from 174 to 576 per 100,000 person-years from 1987 to 2015. Inequality in AF incidence rate ratio between highest and lowest income groups increased from 23% in 1987 to 38% in 2015. We found clustering and geographical variation in AF incidence rates, with incidence rates at municipality level being up to 34% higher than the country mean after adjusting for socioeconomic position. Conclusions Geographical variations and clustering in AF incidence rates exist. Compared to previous studies from Alberta, Canada and the United States, we show that geographical variations exist in a country with free access to healthcare and even when accounting for socioeconomic differences at an individual level. An increasing social inequality in AF was seen from 1987 to 2015. Therefore, when planning prevention strategies, attention to individuals with low income should be given. Further studies focusing on identification of neighbourhood risk factors for AF are needed.

Personality change and environmental concerns

2020 ◽  
Author(s):  
Christopher James Hopwood ◽  
Ted Schwaba ◽  
Wiebke Bleidorn
Keyword(s):  
Personality Traits ◽  
Personality Change ◽  
Environmental Concerns ◽  
Big Five Personality ◽  
German Population ◽  
Individual Level ◽  
Sustainable Behavior ◽  
Nationally Representative ◽  
The Individual ◽  
Over Time

Personal concerns about climate change and the environment are a powerful motivator of sustainable behavior. People’s level of concern varies as a function of a variety of social and individual factors. Using data from 58,748 participants from a nationally representative German sample, we tested preregistered hypotheses about factors that impact concerns about the environment over time. We found that environmental concerns increased modestly from 2009-2017 in the German population. However, individuals in middle adulthood tended to be more concerned and showed more consistent increases in concern over time than younger or older people. Consistent with previous research, Big Five personality traits were correlated with environmental concerns. We present novel evidence that increases in concern were related to increases in the personality traits neuroticism and openness to experience. Indeed, changes in openness explained roughly 50% of the variance in changes in environmental concerns. These findings highlight the importance of understanding the individual level factors associated with changes in environmental concerns over time, towards the promotion of more sustainable behavior at the individual level.

scholarly journals Age and Sex Specific Trends in Incidence of Juvenile Idiopathic Arthritis in Danish Birth Cohorts from 1992 to 2002: A Nationwide Register Linkage Study

2021 ◽  
Vol 18 (16) ◽  
pp. 8331
Author(s):  
Isabel Cardoso ◽  
Peder Frederiksen ◽  
Ina Olmer Specht ◽  
Mina Nicole Händel ◽  
Fanney Thorsteinsdottir ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Regression Model ◽  
Incidence Rate ◽  
Poisson Regression ◽  
Linkage Study ◽  
Incidence Rates ◽  
Age Group ◽  
Poisson Regression Model ◽  
Birth Cohorts ◽  
Age And Sex

This study reports age- and sex-specific incidence rates of juvenile idiopathic arthritis (JIA) in complete Danish birth cohorts from 1992 through 2002. Data were obtained from the Danish registries. All persons born in Denmark, from 1992–2002, were followed from birth and until either the date of first diagnosis recording, death, emigration, 16th birthday or administrative censoring (17 May 2017), whichever came first. The number of incident JIA cases and its incidence rate (per 100,000 person-years) were calculated within sex and age group for each of the birth cohorts. A multiplicative Poisson regression model was used to analyze the variation in the incidence rates by age and year of birth for boys and girls separately. The overall incidence of JIA was 24.1 (23.6–24.5) per 100,000 person-years. The rate per 100,000 person-years was higher among girls (29.9 (29.2–30.7)) than among boys (18.5 (18.0–19.1)). There were no evident peaks for any age group at diagnosis for boys but for girls two small peaks appeared at ages 0–5 years and 12–15 years. This study showed that the incidence rates of JIA in Denmark were higher for girls than for boys and remained stable over the observed period for both sexes.

Canada’s changing innovation landscape

2021 ◽  
Author(s):  
Md. Razib Alam ◽  
Bonwoo Koo ◽  
Brian Paul Cozzarin
Keyword(s):  
The United States ◽  
Destination Country ◽  
Firm Level ◽  
Individual Level ◽  
Patent Classification ◽  
The Usa ◽  
The Government ◽  
The Individual ◽  
The University ◽  
Over Time

Abstract Our objective is to study Canada’s patenting activity over time in aggregate terms by destination country, by assignee and destination country, and by diversification by country of destination. We collect bibliographic patent data from the Canadian Intellectual Property Office and the United States Patent and Trademark Office. We identify 19,957 matched Canada–US patents, 34,032 Canada-only patents, and 43,656 US-only patents from 1980 to 2014. Telecommunications dominates in terms of International Patent Classification technologies for US-only and Canada–US patents. At the firm level, the greatest number of matched Canada–US patents were granted in the field of telecommunications, at the university level in pharmaceuticals, at the government level in control and instrumentation technology, and at the individual level in civil engineering. We use entropy to quantify technological diversification and find that diversification indices decline over time for Canada and the USA; however, all US indices decline at a faster rate.

scholarly journals Discordant Chronic Conditions and Depressive Symptoms: Longitudinal Associations Among Middle-Aged and Older Couples

2019 ◽  
Author(s):  
Courtney A Polenick ◽  
Kira S Birditt ◽  
Angela Turkelson ◽  
Benjamin C Bugajski ◽  
Helen C Kales
Keyword(s):  
Depressive Symptoms ◽  
Marital Quality ◽  
Chronic Conditions ◽  
Later Life ◽  
Well Being ◽  
Middle Aged ◽  
Older Couples ◽  
Individual Level ◽  
The Individual ◽  
Over Time

Abstract Objectives Individuals often manage chronic conditions in middle and later life that may diminish well-being. Little is known, however, about discordant conditions (i.e., two or more conditions with competing self-management requirements) among older couples and their links to depressive symptoms. We considered discordant conditions at both the individual level and the couple level (i.e., between spouses), along with their long-term implications for depressive symptoms. Methods The U.S. sample included 1,116 middle-aged and older couples drawn from five waves (2006–2014) of the Health and Retirement Study. Longitudinal actor-partner interdependence models evaluated whether individual-level and couple-level discordant chronic health conditions were concurrently linked to depressive symptoms, and whether these associations became stronger over time. Models controlled for age, minority status, education, prior wave depressive symptoms, and each partner’s baseline report of negative marital quality and number of chronic conditions in each wave. Results Wives and husbands reported significantly greater depressive symptoms when they had individual-level discordant conditions about 2 years after baseline, and these links intensified over time. Beyond this association, husbands had significantly greater depressive symptoms when there were couple-level discordant conditions. Discussion Individual-level and couple-level discordant conditions may have lasting implications for depressive symptoms during midlife and older adulthood.

The Development of Distinct Choice Process Segments over Time: A Stochastic Modeling Approach

1982 ◽  
Vol 46 (2) ◽  
pp. 48-59 ◽  
Author(s):  
Donald R. Lehmann ◽  
William L. Moore ◽  
Terry Elrod
Keyword(s):  
Decision Making ◽  
Problem Solving ◽  
Stochastic Modeling ◽  
Information Acquisition ◽  
Response Behavior ◽  
Model Framework ◽  
Individual Level ◽  
Amount Of Information ◽  
The Individual ◽  
Over Time

This paper examines Howard's (1963) typology dividing decision making into extensive problem solving (ESP), limited problem solving (LSP), and routinized response behavior (RRB). Specifically, the amount of information accessed in a longitudinal experiment is studied. Information acquisition is modeled stochastically at the individual level, and the existence of two segments (LSP and RRB) is tested in a nested-model framework.

40-Year Trends in Skin Cancer in British Columbia, Canada, 1973 to 2003

2012 ◽  
Vol 16 (2) ◽  
pp. 83-91 ◽  
Author(s):  
David I. Mclean ◽  
Norm Phillips ◽  
Youwen Zhou ◽  
Richard Gallagher ◽  
Tim K. Lee
Keyword(s):  
British Columbia ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Incidence Rate ◽  
Incidence Rates ◽  
Cutaneous Malignant Melanoma ◽  
Skin Cancers ◽  
Canadian Population ◽  
Novel Method ◽  
Over Time

Background: Skin cancer is common in North America. Incidence rate trends are potentially important in the assessment of the effects of measures to increase sun awareness in the population as well as measures to reduce sun damage. Objective: To determine the incidence of basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and cutaneous malignant melanoma (CMM) in a geographically defined Canadian population over a 40-year period. Methods: Data were obtained from the BC Cancer Registry for the calendar years 1973, 1983, 1993, and 2003. Results: Age-standardized incidence rates increased significantly from 1973 to 2003 for BCC, SCC, and CMM. Limitations: The ethnic makeup of British Columbia has changed over time, and a novel method of accounting for the effect of this on skin cancer rates is presented. Conclusion: The incidence rate for skin cancers continued to rise in British Columbia, but there appears to have been a decline in the incidence of CMM and BCC in the youngest cohorts.

A CONNECTIONIST ABM OF SOCIAL CATEGORIZATION PROCESSES

2012 ◽  
Vol 15 (06) ◽  
pp. 1250077 ◽  
Author(s):  
DIRK VAN ROOY
Keyword(s):  
Social Influence ◽  
Network Structure ◽  
Social Adaptation ◽  
Multiple Sources ◽  
Agent Based ◽  
Individual Level ◽  
Extensive Research Program ◽  
Micro Level ◽  
The Individual ◽  
Over Time

This paper introduces a connectionist Agent-Based Model (cABM) that incorporates detailed, micro-level understanding of social influence processes derived from laboratory studies and that aims to contextualize these processes in such a way that it becomes possible to model multidirectional, dynamic influences in extended social networks. At the micro-level, agent processes are simulated by recurrent auto-associative networks, an architecture that has a proven ability to simulate a variety of individual psychological and memory processes [D. Van Rooy, F. Van Overwalle, T. Vanhoomissen, C. Labiouse and R. French, Psychol. Rev. 110, 536 (2003)]. At the macro-level, these individual networks are combined into a "community of networks" so that they can exchange their individual information with each other by transmitting information on the same concepts from one net to another. This essentially creates a network structure that reflects a social system in which (a collection of) nodes represent individual agents and the links between agents the mutual social influences that connect them [B. Hazlehurst, and E. Hutchins, Lang. Cogn. Process. 13, 373 (1998)]. The network structure itself is dynamic and shaped by the interactions between the individual agents through simple processes of social adaptation. Through simulations, the cABM generates a number of novel predictions that broadly address three main issues: (1) the consequences of the interaction between multiple sources and targets of social influence (2) the dynamic development of social influence over time and (3) collective and individual opinion trajectories over time. Some of the predictions regarding individual level processes have been tested and confirmed in laboratory experiments. In a extensive research program, data is currently being collected from real groups that will allow validating the predictions of cABM regarding aggregate outcomes.

A regression method for modelling geometric rates

2015 ◽  
Vol 26 (6) ◽  
pp. 2700-2707 ◽  
Author(s):  
Matteo Bottai
Keyword(s):  
Clinical Trial ◽  
Medical Research ◽  
Incidence Rate ◽  
Poisson Regression ◽  
Regression Method ◽  
Time To Event ◽  
Summary Measure ◽  
Compound Interest ◽  
Event Variable ◽  
Over Time

The occurrence of an event of interest over time is often summarized by the incidence rate, defined as the average number of events per person-time. This type of rate applies to events that may occur repeatedly over time on any given subject, such as infections, and Poisson regression represents a natural regression method for modelling the effect of covariates on it. However, for events that can occur only once, such as death, the geometric rate may be a better summary measure. The geometric rate has long been utilized in demography for studying the growth of populations and in finance to compute compound interest on capital. This type of rate, however, is virtually unknown to medical research. This may be partly a consequence of the lack of a regression method for it. This paper describes a regression method for modelling the effect of covariates on the geometric rate. The described method is based on applying quantile regression to a transform of the time-to-event variable. The proposed method is used to analyze mortality in a randomized clinical trial and in an observational epidemiological study.

Redistribution under the Social Security benefit formula at the individual and household levels, 1992 and 2004

2012 ◽  
Vol 12 (1) ◽  
pp. 1-27 ◽  
Author(s):  
ALAN L. GUSTMAN ◽  
THOMAS L. STEINMEIER ◽  
NAHID TABATABAI
Keyword(s):  
Social Security ◽  
Labor Force Participation ◽  
Social Security Benefit ◽  
Household Level ◽  
Individual Level ◽  
The Social ◽  
High Earning ◽  
Using Data ◽  
The Individual ◽  
Over Time

AbstractStudies using data from the early 1990s suggested that while the progressive Social Security benefit formula succeeded in redistributing benefits from individuals with high earnings to individuals with low earnings, it was much less successful in redistributing benefits from households with high earnings to households with low earnings. Wives often earned much less than their husbands. As a result, much of the redistribution at the individual level was effectively from high earning husbands to their own lower earning wives. In addition, spouse and survivor benefits accrue disproportionately to women from high income households. Both factors mitigate redistribution at the household level. It has been argued that with the increase in the labor force participation and earnings of women, Social Security now should do a better job of redistributing benefits at the household level. To be sure, when we compare outcomes for a cohort with a household member age 51 to 56 in 1992 with those from a cohort born twelve years later, redistribution at the household level has increased over time. Nevertheless, as of 2004 there still is substantially less redistribution of benefits from high to low earning households than from high to low earning individuals.

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