scholarly journals Risk Factors for Surgical Site Infections Following Neurosurgical Spinal Fusion Operations: A Case-Control Study—Methodological issue

2017 ◽  
Vol 38 (8) ◽  
pp. 1013-1014 ◽  
Author(s):  
Erfan Ayubi ◽  
Saeid Safiri
Keyword(s):  
Risk Factors ◽  
Spinal Fusion ◽  
Case Control Study ◽  
Methodological Issue ◽  
Surgical Site Infections ◽  
Case Control ◽  
Control Study

Risk Factors for Surgical Site Infections Following Neurosurgical Spinal Fusion Operations: A Case Control Study

2016 ◽  
Vol 38 (3) ◽  
pp. 340-347 ◽  
Author(s):  
Thomas L. Walsh ◽  
Ashley M. Querry ◽  
Sheila McCool ◽  
Alison L. Galdys ◽  
Kathleen A. Shutt ◽  
...  
Keyword(s):  
Risk Factors ◽  
Spinal Fusion ◽  
Protective Factor ◽  
Case Control Study ◽  
Care Center ◽  
Surgical Site Infections ◽  
Case Control ◽  
Study Cohort ◽  
Retrospective Case ◽  
Control Study

OBJECTIVETo determine risk factors for the development of surgical site infections (SSIs) in neurosurgery patients undergoing spinal fusion.DESIGNRetrospective case-control study.SETTINGLarge, academic, quaternary care center.PATIENTSThe study population included all neurosurgery patients who underwent spinal fusion between August 1, 2009, and August 31, 2013. Cases were defined as patients in the study cohort who developed an SSI. Controls were patients in the study cohort who did not develop an SSI.METHODSTo achieve 80% power with an ability to detect an odds ratio (OR) of 2, we performed an unmatched case-control study with equal numbers of cases and controls.RESULTSDuring the study period, 5,473 spinal fusion procedures were performed by neurosurgeons in our hospital. With 161 SSIs recorded during the study period, the incidence of SSIs associated with these procedures was 2.94%. While anterior surgical approach was found to be a protective factor (OR, 0.20; 95% confidence interval [CI], 0.08–0.52), duration of procedure (OR, 1.58; 95% CI, 1.29–1.93), American Society of Anesthesiologists score of 3 or 4 (OR, 1.79; 95% CI, 1.00–3.18), and hospitalization within the prior 30 days (OR, 5.8; 95% CI, 1.37–24.57) were found in multivariate analysis to be independent predictors of SSI following spinal fusion. Prior methicillin-resistant Staphylococcus aureus (MRSA) nares colonization was highly associated with odds 20 times higher of SSI following spinal fusion (OR, 20.30; 95% CI, 4.64–8.78).CONCLUSIONSIn additional to nonmodifiable risk factors, prior colonization with MRSA is a modifiable risk factor very strongly associated with development of SSI following spinal fusion.Infect Control Hosp Epidemiol 2017;38:348–352

Surgical-Site Infection Following Spinal Fusion: A Case-Control Study in a Children's Hospital

2003 ◽  
Vol 24 (8) ◽  
pp. 591-595 ◽  
Author(s):  
Annie-Claude Labbé ◽  
Anne-Marie Demers ◽  
Ramona Rodrigues ◽  
Vincent Arlet ◽  
Kim Tanguay ◽  
...  
Keyword(s):  
Risk Factors ◽  
Antibiotic Prophylaxis ◽  
Spinal Fusion ◽  
Spinal Surgery ◽  
Case Control Study ◽  
Tertiary Care ◽  
Surgical Site Infections ◽  
Case Control ◽  
Gram Negative Organisms ◽  
Control Study

AbstractObjectives:To determine the rates of surgical-site infections (SSIs) after spinal surgery and to identify the risk factors associated with infection.Design:SSIs had been identified by active prospective surveillance. A case-control study to identify risk factors was performed retrospectively.Setting:University-associated, tertiary-care pediatric hospital.Patients:All patients who underwent spinal surgery between 1994 and 1998. Cases were all patients who developed an SSI after spinal surgery. Controls were patients who did not develop an SSI, matched with the cases for the presence or absence of myelodysplasia and for the surgery date closest to that of the case.Results:There were 10 infections following 125 posterior spinal fusions, 4 infections after 50 combined anterior-posterior fusions, and none after 95 other operations. The infection rate was higher in patients with myelodysplasia (32 per 100 operations) than in other patients (3.4 per 100 operations; relative risk = 9.45; P < .001). Gram-negative organisms were more common in early infections and Staphylococcus aureus in later infections. Most infections occurred in fusion involving sacral vertebrae (odds ratio [OR] = 12.0; P = .019). Antibiotic prophylaxis was more frequently suboptimal in cases than in controls (OR = 5.5; P = .034). Five patients required removal of instrumentation and 4 others required surgical debridement.Conclusions:Patients with myelodysplasia are at a higher risk for SSIs after spinal fusion. Optimal antibiotic prophylaxis may reduce the risk of infection, especially in high-risk patients such as those with myelodysplasia or those undergoing fusion involving the sacral area.

scholarly journals Risk Factors for Surgical Site Infections Following Spinal Fusion Procedures: A Case-Control Study

2011 ◽  
Vol 53 (7) ◽  
pp. 686-692 ◽  
Author(s):  
S. B. Rao ◽  
G. Vasquez ◽  
J. Harrop ◽  
M. Maltenfort ◽  
N. Stein ◽  
...  
Keyword(s):  
Risk Factors ◽  
Spinal Fusion ◽  
Case Control Study ◽  
Surgical Site Infections ◽  
Case Control ◽  
Control Study

Spinal Fusion Surgical Site Infections at an Acute Care Hospital: A Case Control Study

2018 ◽  
Vol 46 (6) ◽  
pp. S43
Author(s):  
Tasha M. Turner ◽  
Shannon Kavish ◽  
Jeanne Yegge ◽  
Katherine Yohnke ◽  
Ashleigh J. Goris ◽  
...  
Keyword(s):  
Spinal Fusion ◽  
Acute Care ◽  
Case Control Study ◽  
Acute Care Hospital ◽  
Surgical Site Infections ◽  
Case Control ◽  
Care Hospital ◽  
Control Study

scholarly journals Propionibacterium acnesinfections in patients with idiopathic scoliosis: a case-control study and review of the literature

2018 ◽  
Vol 12 (2) ◽  
pp. 173-180 ◽  
Author(s):  
I. Swarup ◽  
J. Gruskay ◽  
M. Price ◽  
J. Yang ◽  
J. Blanco ◽  
...  
Keyword(s):  
Risk Factors ◽  
Idiopathic Scoliosis ◽  
Spinal Fusion ◽  
Robust Regression ◽  
Case Control Study ◽  
Propionibacterium Acnes ◽  
Acute Infection ◽  
Case Control ◽  
Index Procedure ◽  
Control Study

PurposeSurgical site infection (SSI) caused by Propionibacterium acnes is an infrequent but devastating complication after spinal fusion. The purpose of this study was to identify risk factors for SSI with Propionibacterium acnes after spinal fusion for juvenile and adolescent idiopathic scoliosis (JIS and AIS).MethodsA case-control study was performed. Each case was matched 2:1 for age, gender and diagnosis. Retrospective chart review was performed to obtain relevant demographic, surgical and clinical data for all cases and controls. Statistical analysis included paired t-test and McNemar test, as well as exact logistic regression and robust regression models.ResultsThis study included ten infection cases (eight AIS, two JIS) and 20 controls (16 AIS, four JIS). In total, six infected cases presented within two weeks of the index procedure (acute infection) and four infected cases presented more than one year from the index procedure (delayed infection). The most common presentation for acute infections was wound drainage, while back pain was more common in delayed infections. All infections were successfully treated with surgical irrigation and debridement and postoperative antibiotics. Hardware was removed for patients with delayed infections. The strongest risk factor for infection was increased requirement for blood transfusion, but it did not reach statistical significance.ConclusionSSI with Propionibacterium acnes is an important complication after spinal fusion for idiopathic scoliosis. These infections can be successfully treated, but larger studies are needed to further identify risk factors and establish standardized guidelines for the treatment and prevention of this complication.Level of Evidence Level III

Risk Factors for Spinal Surgical-Site Infections in a Community Hospital: A Case–Control Study

2003 ◽  
Vol 24 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Anucha Apisarnthanarak ◽  
Marilyn Jones ◽  
Brian M. Waterman ◽  
Cathy M. Carroll ◽  
Robert Bernardi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Case Control Study ◽  
Community Hospital ◽  
Surgical Site Infections ◽  
Case Control ◽  
Site Infection ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery ◽  
Control Study

AbstractObjective:To characterize risk factors for surgical-site infection after spinal surgery.Design:A case–control study.Setting:A 113-bed community hospital.Method:From January 1998 through June 2000, the incidence of surgical-site infection in patients undergoing laminectomy, spinal fusion surgery, or both increased at community hospital. A We compared 13 patients who acquired surgical-site infections after laminectomy, spinal fusion surgery, or both with 47 patients who were operated on during the same time period but did not acquire a surgical-site infection. Information collected included demographics, risk factors, personnel involved in the operations, length of hospital stay, and hospital costs.Results:Of 13 case-patients, 9 (69%) were obese, 9 (69%) had spinal compression, 5 (38.5%) had a history of tobacco use, and 4 (31%) had diabetes. Oxacillin-sensitive Staphylococcus aureus (6 of 13; 46%) was the most common organism isolated. Significant risk factors for postoperative spinal surgical-site infection were dural tear during the surgical procedure and the use of glue to cement the dural patch (3 of 13 [23%] vs 1 of 47 [2.1%] ; P = .02) and American Society of Anesthesiologists risk class of 3 or more (6 of 13 [46.2%] vs 7 of 47 [15%]; P = .02). Case-patients were more likely to have prolonged length of stay (median, 16 vs 4 days; P < .001). The average excess length of stay was 11 days and the excess cost per case was $12,477.Conclusion:Dural tear and the use of glue should be evaluated as potential risk factors for spinal surgical-site infection. Systematic observation for potential lapses in sterile technique and surgical processes that may increase the risk of infection may help prevent spinal surgical-site infection.

Risk factors for esophageal adenocarcinoma: A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
B AVIDAN ◽  
A SONNENBERG ◽  
T SCHNELL ◽  
G CHEJFEC ◽  
A METZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Adenocarcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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