scholarly journals Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections

2018 ◽  
Vol 39 (2) ◽  
pp. 226-228 ◽  
Author(s):  
Robert J. Woods ◽  
Twisha S. Patel ◽  
Jerod L. Nagel ◽  
Duane W. Newton ◽  
Andrew F. Read
Keyword(s):  
Enterococcus Faecium ◽  
Bloodstream Infections ◽  
Infect Control Hosp ◽  
Vancomycin Resistant Enterococcus ◽  
Minimum Inhibitory Concentrations ◽  
Vancomycin Resistant ◽  
Over Time

We report daptomycin minimum inhibitory concentrations (MICs) for vancomycin-resistant Enterococcus faecium isolated from bloodstream infections over a 4-year period. The daptomycin MIC increased over time hospital-wide for initial isolates and increased over time within patients, culminating in 40% of patients having daptomycin-nonsusceptible isolates in the final year of the study.Infect Control Hosp Epidemiol 2018;39:226–228

Activity of Oritavancin Against Gram-positive Pathogens Causing Bloodstream Infections in the United States Over 10 Years: Focus on Drug-Resistant Enterococcal Subsets (2010-2019)

2021 ◽  
Author(s):  
Cecilia G. Carvalhaes ◽  
Helio S. Sader ◽  
Jennifer M. Streit ◽  
Mariana Castanheira ◽  
Rodrigo E. Mendes
Keyword(s):  
United States ◽  
Staphylococcus Aureus ◽  
Enterococcus Faecium ◽  
Bloodstream Infections ◽  
The United States ◽  
Drug Resistant ◽  
Gram Positive ◽  
Methicillin Resistant ◽  
Vancomycin Resistant ◽  
Over Time

Oritavancin displayed potent and stable activity (MIC 90 range, 0.06-0.5 mg/L) over time (2010-2019) against Gram-positive pathogens causing bloodstream infections, including methicillin-resistant Staphylococcus aureus and resistant subsets of Enterococcus spp. Daptomycin and linezolid were also active against methicillin-resistant S. aureus and vancomycin-resistant Enterococcus . Only oritavancin and linezolid remained active against Enterococcus faecium isolates displaying an elevated daptomycin MIC (i.e., 2-4 mg/L). Proportions of methicillin-resistant S. aureus and vancomycin-resistant Enterococcus within the respective S. aureus and enterococcal populations decreased over this period.

scholarly journals Clinical Outcomes of Bloodstream Infections Due to Vancomycin-Resistant Enterococcus faecium

2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
Rachel V. Marini ◽  
Ryan K. Shields ◽  
Lloyd Clarke ◽  
Cornelius J. Clancy ◽  
Minh-Hong Nguyen ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Enterococcus Faecium ◽  
Bloodstream Infections ◽  
Vancomycin Resistant Enterococcus ◽  
Vancomycin Resistant

Colonization pattern of vancomycin-resistant Enterococcus faecium

1994 ◽  
Vol 22 (4) ◽  
pp. 202-206 ◽  
Author(s):  
E YAMAGUCHIE ◽  
F VALENA ◽  
S SMITH ◽  
A SIMMONS ◽  
R ENG
Keyword(s):  
Enterococcus Faecium ◽  
Vancomycin Resistant Enterococcus ◽  
Colonization Pattern ◽  
Vancomycin Resistant
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