scholarly journals Environmental Exposures and the Risk of Central Venous Catheter Complications and Readmissions in Home Infusion Therapy Patients

2016 ◽  
Vol 38 (1) ◽  
pp. 68-75 ◽  
Author(s):  
Sara C. Keller ◽  
Deborah Williams ◽  
Mitra Gavgani ◽  
David Hirsch ◽  
John Adamovich ◽  
...  
Keyword(s):  
Risk Factors ◽  
Parenteral Nutrition ◽  
Total Parenteral Nutrition ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Environmental Exposures ◽  
Infusion Therapy ◽  
Central Venous ◽  
Home Infusion Therapy ◽  
Home Infusion

BACKGROUNDPatients are frequently discharged with central venous catheters (CVCs) for home infusion therapy.OBJECTIVETo study a prospective cohort of patients receiving home infusion therapy to identify environmental and other risk factors for complications.DESIGNProspective cohort study between March and December 2015.SETTINGHome infusion therapy after discharge from academic medical centers.PARTICIPANTSOf 368 eligible patients discharged from 2 academic hospitals to home with peripherally inserted central catheters and tunneled CVCs, 222 consented. Patients remained in the study until 30 days after CVC removal.METHODSPatients underwent chart abstraction and monthly telephone surveys while the CVC was in place, focusing on complications and environmental exposures. Multivariable analyses estimated adjusted odds ratios and adjusted incident rate ratios between clinical, demographic, and environmental risk factors and 30-day readmissions or CVC complications.RESULTSOf 222 patients, total parenteral nutrition was associated with increased 30-day readmissions (adjusted odds ratio, 4.80 [95% CI, 1.51–15.21) and CVC complications (adjusted odds ratio, 2.41 [95% CI, 1.09–5.33]). Exposure to soil through gardening or yard work was associated with a decreased likelihood of readmissions (adjusted odds ratio, 0.09 [95% CI, 0.01–0.74]). Other environmental exposures were not associated with CVC complications.CONCLUSIONScomplications and readmissions were common and associated with the use of total parenteral nutrition. Common environmental exposures (well water, cooking with raw meat, or pets) did not increase the rate of CVC complications, whereas soil exposures were associated with decreased readmissions. Interventions to decrease home CVC complications should focus on total parenteral nutrition patients.Infect Control Hosp Epidemiol 2016;1–8

Outcome of Escherichia coli and/or Klebsiella Bloodstream Infection in Children With Central Venous Catheters

2011 ◽  
Vol 28 (11) ◽  
pp. 1308-1310 ◽  
Author(s):  
Jessica Buckley ◽  
Susan E. Coffin ◽  
Ebbing Lautenbach ◽  
Priya Prasad ◽  
Jaclyn Chu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Escherichia Coli ◽  
Mechanical Ventilation ◽  
Odds Ratio ◽  
Retrospective Cohort ◽  
Adjusted Odds Ratio ◽  
Significant Proportion ◽  
Bloodstream Infections ◽  
Central Venous Catheters ◽  
Central Venous

We conducted a retrospective cohort study of children with catheter-associated bloodstream infections (BSIs) due to Escherichia coli and/or Klebsiella. Risk factors for poor outcome (ie, death or recurrence of infection) were receipt of mechanical ventilation (adjusted odds ratio [aOR], 4.6 [95% confidence interval {CI}, 1.39-16.30]) and receipt of total parenteral nutrition (aOR, 3.5 [95% CI, 1.1-10.8]). A significant proportion of children with catheter-associated BSI were treated successfully without catheter removal.

Prospective Evaluation of Risk Factors for Bloodstream Infection in Patients Receiving Home Infusion Therapy

1999 ◽  
Vol 131 (5) ◽  
pp. 340 ◽  
Author(s):  
Jerome I. Tokars ◽  
Susan T. Cookson ◽  
Margaret A. McArthur ◽  
Cindy L. Boyer ◽  
Allison J. McGeer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bloodstream Infection ◽  
Infusion Therapy ◽  
Prospective Evaluation ◽  
Home Infusion Therapy ◽  
Home Infusion

scholarly journals Epidemiology of hypertension in selected towns of Wollega zones, Western Ethiopia, 2019: A community-based cross-sectional study

2021 ◽  
Vol 9 ◽  
pp. 205031212110245
Author(s):  
Getu Mosisa ◽  
Bikila Regassa ◽  
Bayise Biru
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Alcohol Consumption ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Cross Sectional Study ◽  
Care Providers ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional

Introduction: Hypertension remains an emerging public health problem globally, particularly in developing countries. Age, income level, obesity, alcohol consumption, smoking, vegetables and fruit consumption, physical activity and chat chewing were some risk factors of hypertension. However, there are limited data on the epidemiology of hypertension in Ethiopia. This study aimed to assess Epidemiology of Hypertension among the community of selected towns of Wollega zones. Methods: A community-based cross-sectional study was conducted from 1 to 30 June 2019 in selected towns of Wollega zones. A multistage sampling technique was used to select 840 study participants. Data were collected using the WHO STEP wise approach. The data were coded and entered into EpiData 3, and exported to SPSS version 20.0 for analysis. Bivariate and multivariable logistic regression analyses were conducted. Statistical significance was declared at p-value < 0.05. Results: The study included a total of 838 respondents with a response rate of 99.7%. The prevalence of hypertension was found to be 189 (22.6%) (95% confidence interval = 19.9%–25.2%). Of this, 108 (12.9%) and 81 (9.7%) of female and male were hypertensive, respectively. Age groups of 30–44 years (adjusted odds ratio = 2.65 (1.43, 4.89)), 45–59 years (adjusted odds ratio = 3.55 (1.79, 7.04)), above 60 years (adjusted odds ratio = 2.97 (1.43, 6.18)), having history of alcohol consumption (adjusted odds ratio = 4.29 (2.4, 7.66)), involving in vigorous physical activity (adjusted odds ratio = 0.096 (0.028, 0.33)), not walking to and from the work (adjusted odds ratio = 13.12 (8.34, 20.67)), being overweight (adjusted odds ratio = 1.98 (1.21, 3.25)), inadequate fruits serving per day (adjusted odds ratio = 2.93 (1.75, 4.88)) were significantly associated with hypertension. Conclusion: The prevalence of hypertension was found to be high in the study area. Older age, alcohol consumption, not engaging in vigorous activity, physical inactivity, being overweight and inadequate intake of fruits were found to be risk factors for hypertension. Therefore, health care providers should provide extensive health education and promotion on recommended lifestyle modification to tackle the burden of hypertension.

scholarly journals Invasive Candidiasis in Hospitalized Patients with Major Burns

2022 ◽  
Vol 12 (1) ◽  
pp. 47
Author(s):  
Yi-Ling Lin ◽  
I-Chen Chen ◽  
Jung-Hsing Yen ◽  
Chih-Sheng Lai ◽  
Yueh-Chi Tsai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Invasive Candidiasis ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Total Body Surface Area ◽  
Reference Value ◽  
Hospitalized Patients ◽  
Research Database ◽  
Specific Population ◽  
Total Body

Background: Invasive candidiasis (IC) is a major cause of morbidities and mortality in patients hospitalized with major burns. This study investigated the incidence of IC in this specific population and analyzed the possible risk factors. Materials and Methods: We retrospectively analyzed data from the National Health Insurance Research Database (NHIRD) of Taiwan. We identified 3582 patients hospitalized with major burns on over 20% of their total body surface area (TBSA) during 2000–2013; we further analyzed possible risk factors. Result: IC was diagnosed in 452 hospitalized patients (12.6%) with major burns. In the multivariate analysis, patients older than 50 years (adjusted odds ratio (OR) = 1.96, 95% confidence interval (CI) 1.36–2.82), those of female sex (adjusted OR = 1.33, 95% CI 1.03–1.72), those with burns on the head (adjusted OR = 1.33, 95% CI 1.02–1.73), and those with burns over a greater TBSA had higher risks of IC. Conclusion: Treating IC is crucial in healthcare for major burns. Our study suggests that several risk factors are associated with IC in patients hospitalized with major burns, providing reliable reference value for clinical decisions.

Prospective Evaluation of Percutaneous Central Venous Silastic Catheters in Newborn Infants With Birth Weights of 510 o 3,920 Grams

PEDIATRICS ◽  
1986 ◽  
Vol 78 (2) ◽  
pp. 245-250 ◽  
Author(s):  
Manuel Durand ◽  
Rangasamy Ramanathan ◽  
Bruce Martinelli ◽  
Milagros Tolentino
Keyword(s):  
Parenteral Nutrition ◽  
Total Parenteral Nutrition ◽  
Very Low Birth Weight ◽  
Newborn Infants ◽  
Central Venous Catheters ◽  
Central Venous ◽  
Low Birth Weight Infants ◽  
A Prospective Study ◽  
First Time ◽  
Percutaneous Central Venous Catheters

With improved neonatal survival, especially of very low birth weight infants, our efforts should be directed toward reduction of morbidity. Sick preterm infants require total parenteral nutrition for prolonged periods of time due to extreme prematurity and feeding intolerance. However, the use of surgically placed Broviac catheters has been associated with a high complication rate. A prospective study of 53 percutaneous central venous Silastic catheterizations for administration of total parenteral nutrition was performed in 45 newborn infants. At the time of catheter insertion, 37 babies weighed less than 1,500 g and 19 weighed less than 1,000 g. Percutaneous central venous catheters were placed successfully the first time in 50 of 55 attempts. In three babies, insertion was successful on second attempt. The catheters remained in place for 25.4 ± 16.7 days ([mean ± SD] range two to 80 days). In babies weighing less than 1,000 g, the catheters remained in place for a longer period of time (34.0 ± 18.0; range 12 to 80 days). Sixty-six percent of the catheters were removed electively. There were four cases of bacteremia (7.5%), and the overall incidence of mechanical complications was 26.4%. We conclude that percutaneous central venous catheters can be used safely and effectively in newborn infants for prolonged administration of total parenteral nutrition, especially in neonates weighing less than 1,000 g.

Flow rate accuracy of ambulatory elastomeric and electronic infusion pumps when exposed to height and back pressures experienced during home infusion therapy

2019 ◽  
Vol 16 (8) ◽  
pp. 735-742 ◽  
Author(s):  
Jodie G Hobbs ◽  
Melissa K Ryan ◽  
Aaron Mohtar ◽  
Andrew J Sluggett ◽  
Janet K Sluggett ◽  
...  
Keyword(s):  
Flow Rate ◽  
Infusion Therapy ◽  
Infusion Pumps ◽  
Home Infusion Therapy ◽  
Home Infusion
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