scholarly journals Role of Coinfecting Strains in Recurrent Clostridium difficile Infection

2016 ◽  
Vol 37 (12) ◽  
pp. 1481-1484 ◽  
Author(s):  
Janet Sun ◽  
Tracy Mc Millen ◽  
N. Esther Babady ◽  
Mini Kamboj
Keyword(s):  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Mixed Infection ◽  
Single Case ◽  
Infect Control Hosp ◽  
Toxigenic Strain ◽  
Recurrent Clostridium Difficile Infection

The contribution of mixed infection in recurrent Clostridium difficile infection (CDI) episodes is not known. Among paired isolates from 52 patients, mixed infection due to >1 toxigenic strain of C. difficile was identified in 8% of first episodes. Among recurrences, relapse from 1 or both co-infecting strains was uncommon; it was detected in a single case each.Infect Control Hosp Epidemiol 2016;1481–1484

scholarly journals 187 Emerging Role of Fecal Microbiota Therapy in the Treatment of Recurrent Clostridium difficile Infection in Children

2013 ◽  
Vol 144 (5) ◽  
pp. S-45
Author(s):  
Shashank Garg ◽  
W.F. Fricke ◽  
Mohit Girotra ◽  
Erik C. von Rosenvinge ◽  
Anand Dutta ◽  
...  
Keyword(s):  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Fecal Microbiota ◽  
Recurrent Clostridium Difficile Infection

Self-Administered Home Series Fecal “Minitransplants” for Recurrent Clostridium difficile Infection on a Rectal Remnant

2015 ◽  
Vol 24 (4) ◽  
pp. 531-533 ◽  
Author(s):  
Daniel Popa ◽  
Mihaela Laszlo ◽  
Lidia Ciobanu ◽  
Elena Ucenic ◽  
Manuela Mihalache ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Toxic Megacolon ◽  
Fecal Microbiota ◽  
Recurrent Infections ◽  
Resonance Imaging ◽  
Vaginal Infection ◽  
Fecal Microbiota Transplant ◽  
Recurrent Clostridium Difficile Infection

A fecal microbiota transplant has proved to be an extremely effective method for patients with recurrent infections with Clostridium difficile. We present the case of a 65-year-old female patient with multiple Clostridium difficile infection (CDI) relapses on the rectal remnant, post-colectomy for a CDI-related toxic megacolon. The patient also evidenced associated symptomatic Clostridium difficile vaginal infection. She was successfully treated with serial fecal “minitransplants” (self-administered at home) and metronidazole ovules.Abbreviations: GI: gastrointestinal; MRI: magnetic resonance imaging; CDI: Clostridium difficile infection; FMT: fecal microbiota transplant.

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