scholarly journals Reduction in Acute Respiratory Infection Among Military Trainees: Secondary Effects of a Hygiene-Based Cluster-Randomized Trial for Skin and Soft-Tissue Infection Prevention

2016 ◽  
Vol 37 (9) ◽  
pp. 1118-1120 ◽  
Author(s):  
Eugene V. Millar ◽  
Carey D. Schlett ◽  
Natasha N. Law ◽  
Wei-Ju Chen ◽  
Michael J. D’Onofrio ◽  
...  
2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S238-S238
Author(s):  
Michael D'onofrio ◽  
Carey Schlett ◽  
Eugene Millar ◽  
Tianyuan Cui ◽  
Jeffrey Lanier ◽  
...  

2020 ◽  
Vol 8 (4) ◽  
pp. 1
Author(s):  
Seidu A. Richard

The use of cloth mask or cotton mask by health care works or the general public in infection prevention has been cautions in a large sampled cluster randomized trial of cloth masks compared with medical masks. The study concluded that medical or surgical mask was potent in preventing infection in the hospital setting. A new study however detected greater contamination of COVID-19 on the outer surfaces both surgical mask and cotton or cloth mask than the inner mask surfaces. This study goes contrary to the early studies on the use of surgical mask for infection prevention. This currently study is misleading and distorting the literature on the use of surgical mask in infection prevention. In the current COVID-19 outbreak, it is most anticipate that hospital as well as community prevention of the spread of the disease involves the use of medical mask and not cloth mask.


2012 ◽  
Vol 177 (11) ◽  
pp. 1335-1342 ◽  
Author(s):  
Carey D. Schlett ◽  
Greg A. Grandits ◽  
Eugene V. Millar ◽  
Timothy J. Whitman ◽  
David R. Tribble

2010 ◽  
Vol 31 (12) ◽  
pp. 1207-1215 ◽  
Author(s):  
Timothy J. Whitman ◽  
Rachel K. Herlihy ◽  
Carey D. Schlett ◽  
Patrick R. Murray ◽  
Greg A. Grandits ◽  
...  

Background.Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) causes skin and soft-tissue infection (SSTI) in military recruits.Objective.To evaluate the effectiveness of 2% Chlorhexidine gluconate (CHG)-impregnated cloths in reducing rates of SSTI and S. aureus colonization among military recruits.Design.A cluster-randomized (by platoon), double-blind, controlled effectiveness trial.Setting.Marine Officer Candidate School, Quantico, Virginia, 2007.Participants.Military recruits.Intervention.Application of CHG-impregnated or control (Comfort Bath; Sage) cloths applied over entire body thrice weekly.Measurements.Recruits were monitored daily for SSTI. Baseline and serial nasal and/or axillary swabs were collected to assess S. aureus colonization.Results.Of 1,562 subjects enrolled, 781 (from 23 platoons) underwent CHG-impregnated cloth application and 781 (from 21 platoons) underwent control cloth application. The rate of compliance (defined as application of 50% or more of wipes) at 2 weeks was similar (CHG group, 63%; control group, 67%) and decreased over the 6-week period. The mean 6-week SSTI rate in the CHG-impregnated cloth group was 0.094, compared with 0.071 in the control group (analysis of variance model rate difference, 0.025 ± 0.016; P = .14). At baseline, 43% of subjects were colonized with methicillin-susceptible S. aureus (MSSA), and 2.1% were colonized with MRSA. The mean incidence of colonization with MSSA was 50% and 61% (P = .026) and with MRSA was 2.6% and 6.0% (P = .034) for the CHG-impregnated and control cloth groups, respectively.Conclusions.CHG-impregnated cloths applied thrice weekly did not reduce rates of SSTI among recruits. S. aureus colonization rates increased in both groups but to a lesser extent in those assigned to the CHG-impregnated cloth Intervention. Antecedent S. aureus colonization was not a risk factor for SSTI. Additional studies are needed to identify effective measures for preventing SSTI among military recruits.Clinical Trials Registration.ClinicalTrials.gov identifier: NCT00475930.


Epidemics ◽  
2016 ◽  
Vol 15 ◽  
pp. 38-55 ◽  
Author(s):  
Allison E. Aiello ◽  
Amanda M. Simanek ◽  
Marisa C. Eisenberg ◽  
Alison R. Walsh ◽  
Brian Davis ◽  
...  

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