scholarly journals Circular PSS Strategies: An Exploration of the Integration of Territorial Resources

2019 ◽  
Vol 1 (1) ◽  
pp. 3191-3200
Author(s):  
Estephania Elizabeth Delgadillo Jaime ◽  
Tatiana Reyes Carrillo ◽  
Rupert Baumgartner
Keyword(s):  
Value Creation ◽  
State Of The Art ◽  
Early Stage ◽  
Intangible Resources ◽  
Local Resources ◽  
Product Service ◽  
Relevant Role ◽  
Product Service Systems ◽  
Local Value

AbstractProduct service systems (PSS) are frequently cited as key strategies in the transition towards the circular economy (CE). The main aim of the CE is sustainable development (SD), hence, this paper intends to highlight the importance of considering the territory in the design and implementation of circular PSS strategies for ensuring SD. This research is in an early stage, thus, a literature review was conducted to define the main characteristics of circular PSS, and the concepts of the territory, territorial and local resources from a PSS perspective. In addition, an analysis of the state-of-the-art approach of the integration of the territorial scale in the design and development of PSS strategies was conducted. This study contributes to the understanding of the territory and its relevance in the local value creation in circular PSS strategies. Furthermore, the results highlight the relevant role of collaboration and the importance of intangible resources in the mobilisation of other resources in the design of circular PSS strategies.

State of the art on the role of the Theory of Inventive Problem Solving in Sustainable Product-Service Systems: Past, Present, and Future

2019 ◽  
Vol 212 ◽  
pp. 489-504 ◽  
Author(s):  
Diego Augusto de Jesus Pacheco ◽  
Carla Schwengber ten Caten ◽  
Carlos Fernando Jung ◽  
Helena Victorovna Guitiss Navas ◽  
Virgílio Antônio Cruz-Machado ◽  
...  
Keyword(s):  
Problem Solving ◽  
State Of The Art ◽  
Service Systems ◽  
Product Service ◽  
Sustainable Product ◽  
Product Service Systems

scholarly journals Is There a Place for Immune Checkpoint Inhibitors in Vulvar Neoplasms? A State of the Art Review

2020 ◽  
Vol 22 (1) ◽  
pp. 190
Author(s):  
Fulvio Borella ◽  
Mario Preti ◽  
Luca Bertero ◽  
Giammarco Collemi ◽  
Isabella Castellano ◽  
...  
Keyword(s):  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitors ◽  
State Of The Art ◽  
Checkpoint Inhibitors ◽  
Early Stage ◽  
Survival Rates ◽  
Younger Women ◽  
Multiple Tumor ◽  
Tumor Types

Vulvar cancer (VC) is a rare neoplasm, usually arising in postmenopausal women, although human papilloma virus (HPV)-associated VC usually develop in younger women. Incidences of VCs are rising in many countries. Surgery is the cornerstone of early-stage VC management, whereas therapies for advanced VC are multimodal and not standardized, combining chemotherapy and radiotherapy to avoid exenterative surgery. Randomized controlled trials (RCTs) are scarce due to the rarity of the disease and prognosis has not improved. Hence, new therapies are needed to improve the outcomes of these patients. In recent years, improved knowledge regarding the crosstalk between neoplastic and tumor cells has allowed researchers to develop a novel therapeutic approach exploiting these molecular interactions. Both the innate and adaptive immune systems play a key role in anti-tumor immunesurveillance. Immune checkpoint inhibitors (ICIs) have demonstrated efficacy in multiple tumor types, improving survival rates and disease outcomes. In some gynecologic cancers (e.g., cervical cancer), many studies are showing promising results and a growing interest is emerging about the potential use of ICIs in VC. The aim of this manuscript is to summarize the latest developments in the field of VC immunoncology, to present the role of state-of-the-art ICIs in VC management and to discuss new potential immunotherapeutic approaches.

scholarly journals Systems Design Perspective of Healthcare Provision in Humanitarian Aid

2014 ◽  
Vol 7 (3) ◽  
Author(s):  
Ana Laura Santos ◽  
Linda S.G.L. Wauben
Keyword(s):  
Medical Equipment ◽  
Systems Design ◽  
Healthcare Provision ◽  
Emergency Relief ◽  
Systems Perspective ◽  
Product Service ◽  
And Performance ◽  
Relief Organizations ◽  
Product Service Systems

This study focuses on the role of Systems Design in addressing the challenges of healthcare provision by international emergency relief organizations in developing countries. More specifically the challenges related to the safety and performance of medical equipment that is transferred in the aftermath of a humanitarian crisis. The aim of this paper is to describe the transfer of medical equipment and its associated challenges from a systems perspective and to reflect on the value of Systems Design as an approach to humanitarian innovation, addressing the identified systemic challenges. The concepts of Human Factors and Ergonomics, and Product-Service Systems will be presented as valuable contributions to support designers in handling a larger degree of complexity throughout the design process and to support them to make informed choices regarding this particular context.

State-of-the-art of design, evaluation, and operation methodologies in product service systems

2016 ◽  
Vol 77 ◽  
pp. 1-14 ◽  
Author(s):  
Min Qu ◽  
Suihuai Yu ◽  
Dengkai Chen ◽  
Jianjie Chu ◽  
Baozhen Tian
Keyword(s):  
State Of The Art ◽  
Service Systems ◽  
Design Evaluation ◽  
Product Service ◽  
Product Service Systems

scholarly journals Towards a Lean Product Service Systems (PSS) Design: State of the Art, Opportunities and Challenges

Procedia CIRP ◽  
2015 ◽  
Vol 30 ◽  
pp. 191-196 ◽  
Author(s):  
Claudio Sassanelli ◽  
Giuditta Pezzotta ◽  
Monica Rossi ◽  
Sergio Terzi ◽  
Sergio Cavalieri
Keyword(s):  
State Of The Art ◽  
Service Systems ◽  
Product Service ◽  
Product Service Systems
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