scholarly journals Are Iranian Sulfur Mustard Gas-Exposed Survivors More Vulnerable to SARS-CoV-2? Some Similarity in Their Pathogenesis

Author(s):  
Gholamreza Farnoosh ◽  
Mostafa Ghanei ◽  
Hossein Khorramdelazad ◽  
Gholamhossein Alishiri ◽  
Alireza Jalali Farahani ◽  
...  

ABSTRACT Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged as a health problem worldwide. It seems that COVID-19 is more lethal for Iranian veterans with a history of exposure to mustard gas. There are some similarities in the pathogenesis of SARS-CoV-2 and mustard gas in immune system disruption and pulmonary infection. SARS-CoV-2 and mustard gas inducing oxidative stress, immune system dysregulation, cytokine storm, and overexpression of angiotensin-converting enzyme II (ACE2) receptor in lungs that act as functional entry receptors for SARS-CoV-2. Moreover, Iranian survivors of mustard gas exposure are more susceptible and vulnerable to COVID-19. It is suggested that the principles of COVID-19 infection prevention and control be adhered to more stringently in Iranian survivors of mustard gas exposure than others who have not been exposed to mustard gas. Therefore, in this review, we discuss the different pathologic aspects of lung injury caused by mustard gas and also the relationship between this damage and the increased susceptibility of Iranian mustard gas exposed survivors to COVID-19.

2020 ◽  
Vol 16 (2) ◽  
pp. 69-74
Author(s):  
Lisa McLean ◽  
Louise Forrester

Mental Health inpatient units have a primary purpose of treating mental health problems, managing disturbance and promoting social contact and support networks. These factors can conflict with optimal infection prevention and control (IPC) measures.<br/> This commentary describes an IPC perspective of the challenges in managing the effects of the COVID-19 pandemic that are specific to acute mental health settings. It points out the main areas for IPC and mental health practice development.<br/> The need for a new paradigm in the relationship between IPC and mental health specialists is identified. Recent collaboration between mental health and IPC specialists in evaluating personal protective equipment (PPE) for use in restraint is outlined.


2019 ◽  
Author(s):  
Asep Rahmadiana ◽  
Ati Surya Mediawati ◽  
Irman Somantri

Background: Infection Prevention and Control Program (ICP) is very important to be implemented in hospitals to protect patients, officers, visitors, and families from the risk of infection. IPCLN (Infection Prevention and Control Link Nurse) as a PPI program implementer in a hospital is expected to be able to carry out its duties to monitor health personnel compliance with standard precautions. Objectives:This study aims to identify the relationship between nurses’ perceptions of IPCLN supervision and compliance withhandhygieneofnursesattheHospitalinTasikmalayaCity. Methods:The research method used is quantitative research with descriptive correlation design usinga cross sectional approach with a population of implementing nurses in 16 inpatients with a totalsampleof152implementingnurses.Analysisofresearchdatawithnonparametric statistics, with Mann Whitney’s test. Results: Results nurse’s perception of effective IPCLN supervision was 50.7%, and adhrence hand hygiene is mean 69.96%. The relationship between IPCLN supervision and compliance with hand hygiene ρ-value 0.006. Conclusion: The implications of this study indicate that nurses ’perceptions of effective supervision will be able to improve compliance with nurses’ hand hygiene when taking nursing care actions. To hospital management, there needs to be an increase in understanding of IPCLN about the importance of supervising implementing nurses when providing care with resocialization of tasks and IPCLN functions.  


Author(s):  
Christian Boeing ◽  
Carlos L. Correa-Martinez ◽  
Franziska Schuler ◽  
Alexander Mellmann ◽  
André Karch ◽  
...  

Given the increasing relevance of VRE as nosocomial pathogens worldwide, infection prevention and control measures, including patient isolation and contact precautions, are indispensable to avoid their spread in the hospital setting. In this study, we developed and validated the PREVENT score, a tool for rapid risk assessment of VRE persistence in patients with a history of previous VRE colonization.


2020 ◽  
Vol 25 (12) ◽  
pp. 2-7
Author(s):  
Alison Phillis

The global desire to produce and deploy a safe and effective vaccine to protect against SARS-CoV-2 infection and the morbidity and mortality subsequent to COVID-19 is unprecedented. The unparalleled speed of research development and access to funding is perhaps equally unique in the history of therapeutic achievement. This article, the third in a series of dedicated to exploring the origins and developments of SARS-CoV-2 within the context of the strategies of infection prevention and control, investigates the theatre behind the extraordinary efforts underpinning the research for therapeutic interventions to halt the COVID-19 pandemic. The Chair of the UK Vaccine Taskforce has stated that the exit strategy depends on a vaccine that is effective in reducing mortality, improving population health by reducing serious disease and protecting the NHS and social care system. This article introduces the major COVID-19 vaccine contenders and considers the challenges and opportunities of an effective global vaccination strategy.


2020 ◽  
Author(s):  
Daniel Poremski ◽  
Sandra Henrietta Subner ◽  
Grace Lam Fong Kin ◽  
Raveen Dev Ram Dev ◽  
Mok Yee Ming ◽  
...  

The Institute of Mental Health in Singapore continues to attempt to prevent the introduction of COVID-19, despite community transmission. Essential services are maintained and quarantine measures are currently unnecessary. To help similar organizations, strategies are listed along three themes: sustaining essential services, preventing infection, and managing human and consumable resources.


2019 ◽  
Vol 15 (2) ◽  
Author(s):  
Walelegn Worku Yallew ◽  
Abera Kumie ◽  
Feleke Moges Yehuala

Healthcare workers have good perception towards infection prevention, but there has been a poor practice towards it. Therefore, the aim of this study was to explore barriers to practice of infection prevention and control practice in teaching hospitals in Amhara region. A phenomenological approach used to explore the lived experience of healthcare workers and management staffs towards infection prevention practice and control. The data was collected from ten in-depth interviews and 23 focus group discussion participants, by face to face interview using open ended interview performed in safe and quiet places. Data was managed using OpenCode software version 4.03 and contents were analyzed thematically. Totally ten different barriers were identified, such as availability of facilities, shortage of material supply, lack of maintenance of facilities and equipment, high patient flow, experience, emergency situation, healthcare worker behaviour and healthcare worker’s information about infection prevention, low awareness of patients and visitors and overflow of families and visitors to the hospital. For effective infection prevention practice implementation, barriers should be considered via identifying specific organizational, healthcare worker, patients and visitors as targets.


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