scholarly journals Biomarkers and indoor air quality: A translational research review

2020 ◽  
pp. 1-10
Author(s):  
Araliya M. Senerat ◽  
Sheila M. Manemann ◽  
Nicholas S. Clements ◽  
Robert D. Brook ◽  
Leslie C. Hassett ◽  
...  
Keyword(s):  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
High Sensitivity ◽  
Air Pollutant ◽  
Research Review ◽  
Mortality And Morbidity ◽  
Reactive Protein ◽  
Indoor Air Pollutants ◽  
The Impact

Abstract Introduction: Air pollution is linked to mortality and morbidity. Since humans spend nearly all their time indoors, improving indoor air quality (IAQ) is a compelling approach to mitigate air pollutant exposure. To assess interventions, relying on clinical outcomes may require prolonged follow-up, which hinders feasibility. Thus, identifying biomarkers that respond to changes in IAQ may be useful to assess the effectiveness of interventions. Methods: We conducted a narrative review by searching several databases to identify studies published over the last decade that measured the response of blood, urine, and/or salivary biomarkers to variations (natural and intervention-induced) of changes in indoor air pollutant exposure. Results: Numerous studies reported on associations between IAQ exposures and biomarkers with heterogeneity across study designs and methods. This review summarizes the responses of 113 biomarkers described in 30 articles. The biomarkers which most frequently responded to variations in indoor air pollutant exposures were high sensitivity C-reactive protein (hsCRP), von Willebrand Factor (vWF), 8-hydroxy-2′-deoxyguanosine (8-OHdG), and 1-hydroxypyrene (1-OHP). Conclusions: This review will guide the selection of biomarkers for translational studies evaluating the impact of indoor air pollutants on human health.

scholarly journals INDOOR AIR QUALITY AT HIGHER INSTITUTION’S LABORATORY: A STUDY ON PRE-SYMPTOMS, AWARENESS AND UNDERSTANDING AMONG OCCUPANTS

2015 ◽  
Vol 77 (1) ◽  
Author(s):  
Mohamad Romizan Osman ◽  
Azman Azid ◽  
Hafizan Juahir ◽  
Kamaruzzaman Yunus ◽  
Mohammad Azizi Amran ◽  
...  
Keyword(s):  
Air Quality ◽  
Discriminant Analysis ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Health Problem ◽  
Air Pollutants ◽  
Personality Tests ◽  
Higher Institution ◽  
Indoor Air Pollutants ◽  
The Impact

This study intends to show the effectiveness of indoor air quality (IAQ) at the higher institution laboratory. The objective is to determine the impact of current IAQ, to study the occupants’ knowledge in the indoor air pollutants and to identify the significance of occupants’ personality regarding the IAQ awareness. 100 respondents had responded to answer the questionnaires given. The questionnaires were analysed using XLSTAT2014 software for descriptive statistic and discriminant analysis in order to fulfil the outlined objectives. The finding shows that 56% of the respondents know about IAQ, while 40% and 4% did not know and not sure about the IAQ, respectively. By gender, there were 20 of male respondents having the IAQ knowledge and 21 of male respondents did not know about the IAQ. Meanwhile, 36 of female respondents have IAQ knowledge, 19 of female respondents did not know the IAQ knowledge and 4 of female respondents were not sure regarding the IAQ knowledge. Furthermore, the IAQ in the laboratory at the higher institution is considered as unhealthy based on the respondents’ complaints of their health problem symptoms. Meanwhile, the results of personality tests show that women have more IAQ awareness compared to men. It indicated that the personalities of the occupants have significance to influence and able to determine their awareness on the IAQ. Hence, it described that IAQ is a significant factor to determine and influence the health of laboratory occupants.

scholarly journals Effects of Climatic Conditions, Season and Environmental Factors on CO2 Concentrations in Naturally Ventilated Primary Schools in Chile

2021 ◽  
Vol 13 (8) ◽  
pp. 4139
Author(s):  
Muriel Diaz ◽  
Mario Cools ◽  
Maureen Trebilcock ◽  
Beatriz Piderit-Moreno ◽  
Shady Attia
Keyword(s):  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Primary Schools ◽  
Co2 Concentration ◽  
Building Design ◽  
Climatic Conditions ◽  
Indoor Environmental Quality ◽  
Co2 Concentrations ◽  
The Impact

Between the ages of 6 and 18, children spend between 30 and 42 h a week at school, mostly indoors, where indoor environmental quality is usually deficient and does not favor learning. The difficulty of delivering indoor air quality (IAQ) in learning facilities is related to high occupancy rates and low interaction levels with windows. In non-industrialized countries, as in the cases presented, most classrooms have no mechanical ventilation, due to energy poverty and lack of normative requirements. This fact heavily impacts the indoor air quality and students’ learning outcomes. The aim of the paper is to identify the factors that determine acceptable CO2 concentrations. Therefore, it studies air quality in free-running and naturally ventilated primary schools in Chile, aiming to identify the impact of contextual, occupant, and building design factors, using CO2 concentration as a proxy for IAQ. The monitoring of CO2, temperature, and humidity revealed that indoor air CO2 concentration is above 1400 ppm most of the time, with peaks of 5000 ppm during the day, especially in winter. The statistical analysis indicates that CO2 is dependent on climate, seasonality, and indoor temperature, while it is independent of outside temperature in heated classrooms. The odds of having acceptable concentrations of CO2 are bigger when indoor temperatures are high, and there is a need to ventilate for cooling.

scholarly journals Window operation behaviour and indoor air quality during lockdown: A monitoring-based simulation-assisted study in London

2021 ◽  
pp. 014362442110177
Author(s):  
Farhang Tahmasebi ◽  
Yan Wang ◽  
Elizabeth Cooper ◽  
Daniel Godoy Shimizu ◽  
Samuel Stamp ◽  
...  
Keyword(s):  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Energy Demand ◽  
Natural Ventilation ◽  
Probabilistic Models ◽  
Performance Model ◽  
Outdoor Environment ◽  
Ventilation Strategies ◽  
The Impact

The Covid-19 outbreak has resulted in new patterns of home occupancy, the implications of which for indoor air quality (IAQ) and energy use are not well-known. In this context, the present study investigates 8 flats in London to uncover if during a lockdown, (a) IAQ in the monitored flats deteriorated, (b) the patterns of window operation by occupants changed, and (c) more effective ventilation patterns could enhance IAQ without significant increases in heating energy demand. To this end, one-year’s worth of monitored data on indoor and outdoor environment along with occupant use of windows has been used to analyse the impact of lockdown on IAQ and infer probabilistic models of window operation behaviour. Moreover, using on-site CO2 data, monitored occupancy and operation of windows, the team has calibrated a thermal performance model of one of the flats to investigate the implications of alternative ventilation strategies. The results suggest that despite the extended occupancy during lockdown, occupants relied less on natural ventilation, which led to an increase of median CO2 concentration by up to 300 ppm. However, simple natural ventilation patterns or use of mechanical ventilation with heat recovery proves to be very effective to maintain acceptable IAQ. Practical application: This study provides evidence on the deterioration of indoor air quality resulting from homeworking during imposed lockdowns. It also tests and recommends specific ventilation strategies to maintain acceptable indoor air quality at home despite the extended occupancy hours.

The impact of mechanical ventilation operation strategies on indoor CO2 concentration and air exchange rates in residential buildings

2020 ◽  
pp. 1420326X2096076
Author(s):  
Pedro F. Pereira ◽  
Nuno M. M. Ramos
Keyword(s):  
Mechanical Ventilation ◽  
Air Quality ◽  
Exchange Rates ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Residential Buildings ◽  
Ventilation Strategy ◽  
The Impact ◽  
Mechanical Extraction ◽  
Air Exchange

In Portugal, residential buildings commonly have their ventilation strategy changed after commissioning. This occurs due to the building managers' willingness to reduce shared costs with the electricity needed for fan operation. However, this option is not technically supported, and the effects of such a strategy on indoor air quality-related to human pollutants are yet to be quantified. CO2 was monitored in 15 bedrooms and air exchange rates were calculated for each room. The air exchange rate values ranged from 0.18 to 0.53 h−1 when mechanical extraction ventilation was off, and from 0.45 to 0.90 h−1 when mechanical extraction ventilation was on, which represents an average increase of 119%. With the current intermittent ventilation strategy, all rooms remain above 1500 ppm for a given percentage of time, and 12 rooms presenting CO2 concentrations above 2000 ppm. Simulations of theoretical CO2 concentrations, for a non-interrupted mechanical ventilation strategy show that no rooms would accumulate CO2 concentrations above 2000 ppm, and only 25% would present CO2 concentrations above 1500 ppm. Pearson correlations between the monitored CO2 and human and spatial factors identified two relevant parameters. Those parameters correspond to ratios between CO2 generation and floor area ([Formula: see text]), and airflow with CO2 generation ([Formula: see text]). The proposed ratios could be used as ways to optimise ventilation costs and indoor air quality.

scholarly journals First steps in the development of a possible measurement method to estimate the radon concentration as an indicator of the indoor air quality

2014 ◽  
Vol 29 (suppl.) ◽  
pp. 52-58
Author(s):  
Franz Roessler ◽  
Jai Azzam ◽  
Volker Grimm ◽  
Hans Hingmann ◽  
Tina Orovwighose ◽  
...  
Keyword(s):  
Exchange Rate ◽  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Primary Energy ◽  
Air Pollutant ◽  
Daily Routine ◽  
Air Exchange Rate ◽  
Pollutant Concentrations ◽  
Air Exchange

The energy conservation regulation provides upper limits for the annual primary energy requirements for new buildings and old building renovation. The actions required could accompany a reduction of the air exchange rate and cause a degradation of the indoor air quality. In addition to climate and building specific aspects, the air exchange rate is essentially affected by the residents. Present methods for the estimation of the indoor air quality can only be effected under test conditions, whereby the influence of the residents cannot be considered and so an estimation under daily routine cannot be ensured. In the context of this contribution first steps of a method are presented, that allows an estimation of the progression of the air exchange rate under favourable conditions by using radon as an indicator. Therefore mathematical connections are established that could be affirmed practically in an experimental set-up. So this method could provide a tool that allows the estimation of the progression of the air exchange rate and in a later step the estimation of a correlating progression of air pollutant concentrations without limitations of using the dwelling.

scholarly journals Indoor air quality improvement and purification by atmospheric pressure Non-Thermal Plasma (NTP)

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Prince Junior Asilevi ◽  
Patrick Boakye ◽  
Sampson Oduro-Kwarteng ◽  
Bernard Fei-Baffoe ◽  
Yen Adams Sokama-Neuyam
Keyword(s):  
Air Quality ◽  
Built Environment ◽  
Indoor Air Quality ◽  
Removal Efficiency ◽  
Indoor Air ◽  
Thermal Plasma ◽  
Processing Parameters ◽  
Optimum Conditions ◽  
Non Thermal Plasma ◽  
The Impact

AbstractNon-thermal plasma (NTP) is a promising technology for the improvement of indoor air quality (IAQ) by removing volatile organic compounds (VOCs) through advanced oxidation process (AOP). In this paper, authors developed a laboratory scale dielectric barrier discharge (DBD) reactor which generates atmospheric NTP to study the removal of low-concentration formaldehyde (HCHO), a typical indoor air VOC in the built environment associated with cancer and leukemia, under different processing conditions. Strong ionization NTP was generated between the DBD electrodes by a pulse power zero-voltage switching flyback transformer (ZVS-FBT), which caused ionization of air molecules leading to active species formation to convert HCHO into carbon dioxide (CO2) and water vapor (H2O). The impact of key electrical and physical processing parameters i.e. discharge power (P), initial concentration (Cin), flow rate (F), and relative humidity (RH) which affect the formaldehyde removal efficiency (ɳ) were studied to determine optimum conditions. Results show that, the correlation coefficient (R2) of removal efficiency dependence on the processing parameters follow the order R2 (F) = 0.99 > R2 (RH) = 0.96, > R2 (Cin) = 0.94 > R2 (P) = 0.93. The removal efficiency reached 99% under the optimum conditions of P = 0.6 W, Cin = 0.1 ppm, F = 0.2 m3/h, and RH = 65% with no secondary pollution. The study provided a theoretical and experimental basis for the application of DBD plasma for air purification in the built environment.

scholarly journals Efficiency and Eco-Costs of Air Purifiers in Terms of Improving Microbiological Indoor Air Quality in Dwellings—A Case Study

Atmosphere ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 742 ◽  
Author(s):  
Ewa Brągoszewska ◽  
Magdalena Bogacka ◽  
Krzysztof Pikoń
Keyword(s):  
Air Pollution ◽  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Pollution Prevention ◽  
Average Concentration ◽  
Environmental Cost ◽  
Bacterial Aerosol ◽  
The Impact ◽  
Ecological Cost

Air pollution, a by-product of economic growth, generates an enormous environmental cost in Poland. The issue of healthy living spaces and indoor air quality (IAQ) is a global concern because people spend approximately 90% of their time indoors. An increasingly popular method to improve IAQ is to use air purifiers (APs). Indoor air is often polluted by bioaerosols (e.g., viruses, bacteria, fungi), which are a major concern for public health. This work presents research on culturable bacterial aerosol (CBA) samples collected from dwellings with or without active APs during the 2019 summer season. The CBA samples were collected using a six-stage Andersen cascade impactor (ACI). The CBA concentrations were expressed as Colony Forming Units (CFU) per cubic metre of air. The average concentration of CBA in dwellings when the AP was active was 450–570 CFU/m3, whereas the average concentration when the AP was not active was 920–1000 CFU/m3. IAQ, when the APs were active, was on average almost 50% better than in cases where there were no procedures to decrease the concentration of air pollutants. Moreover, the obtained results of the particle size distribution (PSD) of CBA indicate that the use of APs reduced the proportion of the respirable fraction (the particles < 3.3 µm) by about 16%. Life cycle assessment (LCA) was used to assess the ecological cost of air purification. Our conceptual approach addresses the impact of indoor air pollution on human health and estimates the ecological cost of APs and air pollution prevention policies.

scholarly journals Indoor air quality and health in schools

2014 ◽  
Vol 40 (3) ◽  
pp. 259-268 ◽  
Author(s):  
Ana Maria da Conceição Ferreira ◽  
Massano Cardoso
Keyword(s):  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Respiratory Diseases ◽  
Reference Value ◽  
Signs And Symptoms ◽  
Co2 Concentration ◽  
Air Pollutant ◽  
Carbon Dioxide Co2 ◽  
The City

Objective: To determine whether indoor air quality in schools is associated with the prevalence of allergic and respiratory diseases in children. Methods: We evaluated 1,019 students at 51 elementary schools in the city of Coimbra, Portugal. We applied a questionnaire that included questions regarding the demographic, social, and behavioral characteristics of students, as well as the presence of smoking in the family. We also evaluated the indoor air quality in the schools. Results: In the indoor air of the schools evaluated, we identified mean concentrations of carbon dioxide (CO2) above the maximum reference value, especially during the fall and winter. The CO2 concentration was sometimes as high as 1,942 ppm, implying a considerable health risk for the children. The most prevalent symptoms and respiratory diseases identified in the children were sneezing, rales, wheezing, rhinitis, and asthma. Other signs and symptoms, such as poor concentration, cough, headache, and irritation of mucous membranes, were identified. Lack of concentration was associated with CO2 concentrations above the maximum recommended level in indoor air (p = 0.002). There were no other significant associations. Conclusions: Most of the schools evaluated presented with reasonable air quality and thermal comfort. However, the concentrations of various pollutants, especially CO2, suggest the need for corrective interventions, such as reducing air pollutant sources and improving ventilation. There was a statistically significant association between lack of concentration in the children and exposure to high levels of CO2. The overall low level of pollution in the city of Coimbra might explain the lack of other significant associations.

Quantifying the impact of traffic-related air pollution on the indoor air quality of a naturally ventilated building

2016 ◽  
Vol 89-90 ◽  
pp. 138-146 ◽  
Author(s):  
Zheming Tong ◽  
Yujiao Chen ◽  
Ali Malkawi ◽  
Gary Adamkiewicz ◽  
John D. Spengler
Keyword(s):  
Air Pollution ◽  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
The Impact
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