scholarly journals 4559 TX TM: Formalization and Institutional Investment in a Model Designed to Advance Research Translational to Community Transformation

2020 ◽  
Vol 4 (s1) ◽  
pp. 120-120
Author(s):  
Tabia Henry Akintobi ◽  
Tabia Henry Akintobi ◽  
Breana Blaess ◽  
Brittaney Bethea ◽  
Virginia Floyd ◽  
...  
Keyword(s):  
Translational Research ◽  
Human Subjects ◽  
Institutional Investment ◽  
Funding Mechanism ◽  
School Of Medicine ◽  
Scientific Philosophy ◽  
Interdisciplinary Approaches ◽  
Study Population ◽  
Institutional Landscape ◽  
Research Faculty

OBJECTIVES/GOALS: Morehouse School of Medicine (MSM), TxTM is a scientific philosophy promoting interdisciplinary approaches towards exponential advances in community and population health. Objectives are to detail the model, pilot funding mechanism, early research findings and infrastructure investments. METHODS/STUDY POPULATION: The health research system has widely acknowledged challenges that can delay research translation to systems that advance health for chronically disadvantaged health disparity population groups. MSM’s vision is to lead the creation and advancement of health equity. The vision-aligned strategic plan prioritized formalization of a TX TM implementation priority. The study population was the institution’s research faculty and leaders, research administration, and communication arm. Through a cross-institutional working group, a plan was deployed to 1) assess the institutional landscape, 2) review the grey and peer reviewed literature on translational research and 3) invest in a pilot research funding mechanism. RESULTS/ANTICIPATED RESULTS: Over $700K has been invested in TX TM implementation. Over half of research faculty completed an institutional landscape assessment to identify translational research expertise, interests and points of interest in new collaboration. The most frequently cited collaborative research interests were clinical research with human subjects, patient-centered outcomes and laboratory-based research with human subjects/specimens. Funded multidisciplinary and/or community-engaged pilot studies investigate the role for circadian rhythms and shift work, cultural variables influencing mental health among Haitians living in the US and integrating prescription reconciliation telehealth in primary care. DISCUSSION/SIGNIFICANCE OF IMPACT: TX TM requires interdisciplinary collaboration across translational research spheres and beyond the academy. Institutional investment, infrastructure support and senior-level champions are central to awareness and rewarding such scholarship towards scaling approaches that advance health equity. CONFLICT OF INTEREST DESCRIPTION: Coined at Morehouse School of Medicine (MSM), Tx TM symbolizes an approach and scientific philosophy designed to intentionally promote and support convergence of interdisciplinary approaches and scientists to stimulate exponential advances for the health of diverse communities.

scholarly journals Establishing the Morehouse School of Medicine (MSM) R-CENTER Clinical and Translational Research Web-Portal: The Role of Focus Groups

2011 ◽  
Vol 22 (4A) ◽  
pp. 165-173 ◽  
Author(s):  
Alexander Quarshie ◽  
Adam Davis ◽  
Gregory Strayhorn ◽  
Carolyn Weaver ◽  
Cigdem Delano ◽  
...  
Keyword(s):  
Focus Groups ◽  
Translational Research ◽  
Web Portal ◽  
School Of Medicine ◽  
Clinical And Translational Research

scholarly journals 2292 Evaluating the impact of a K-award on clinical and translational research

2018 ◽  
Vol 2 (S1) ◽  
pp. 55-55
Author(s):  
Elias M. Samuels ◽  
Thomas E. Perorazio ◽  
Ellen Champagne ◽  
Brenda Eakin
Keyword(s):  
Translational Research ◽  
Research Training ◽  
Research Support ◽  
Research Experiences ◽  
Research Careers ◽  
Study Population ◽  
The Impact ◽  
Over Time ◽  
Clinical And Translational Research ◽  
Research Service

OBJECTIVES/SPECIFIC AIMS: Identify the impact of the provision of clinical and translational research training awards on investigators’ pursuit of clinical and translational research careers. METHODS/STUDY POPULATION: Propensity score matching and qualitative analysis/investigators receiving MICHR’s KL2 research training awards. RESULTS/ANTICIPATED RESULTS: While the evaluations of the impact of this service have shown participants find them to be valuable it is expected that participation in the workshop may be more beneficial to investigators with certain types of prior research experiences and who utilize more CTSA research support. DISCUSSION/SIGNIFICANCE OF IMPACT: Because this evaluation of a research service incorporate data representing investigator’s receipt of different CTSA resources, the findings can be used to inform the ongoing coordination of these services in ways that optimize their impact on the production of clinical and translational research. There is an enduring need for evaluations of CTSA programs to account for investigators’ use of different constellations of research services in order to identify what combinations of services over time are most effective at fostering successful clinical and translational research careers.

scholarly journals 2490 Research navigation services and onboarding: Succeeding in the research environment

2018 ◽  
Vol 2 (S1) ◽  
pp. 59-60
Author(s):  
Rebecca Namenek Brouwer ◽  
Geeta Swamy
Keyword(s):  
New Faculty ◽  
Research Areas ◽  
School Of Medicine ◽  
Start Up ◽  
Other Information ◽  
Innovation And Technology ◽  
Study Population ◽  
Consultative Service ◽  
Navigation Service ◽  
Funding Opportunities

OBJECTIVES/SPECIFIC AIMS: Describe (1) the components of the research navigation service and consultation/onboarding program, (2) use and adoption of the services, and (3) the overall satisfaction from the research community. METHODS/STUDY POPULATION: Duke offers 2 programs to support researchers: Research Navigation and Researcher Onboarding. The services aim to connect researchers to resources, offices, funding opportunities, and other collaborators. The general Research Navigation Service is an on-demand “hotline,” where navigators answer questions from researchers across the institution, helping them understand processes, best practices, and how to locate resources or potential collaborators. Navigators can be reached via the myRESEARCHhome portal, email, or by phone. The researcher onboarding program is a free 1:1 consultative service, focused on the researcher’s individual portfolio, stage of career, and immediate plans in the research arena. The goal is to equip researchers “from the start” to be successful. Researchers are identified via the new faculty hire list, or by referral. Both services are provided by the myRESEARCHnavigators team, who are trained in a variety of research areas, from basic to clinical to social sciences, and are familiar with Duke. RESULTS/ANTICIPATED RESULTS: Use of both services has increased substantially over the year. Of the almost 200 faculty members hired into the School of Medicine in 2017, ~75% have taken part in the onboarding program, and 91% have rated the service as 5-stars. The content of the sessions will be described. The Research Navigation service has fielded hundreds of calls since its inception, with topics including Equipment and Facilities (55 requests), Study start up (44 requests), Innovation and Technology (15 requests), and Regulation and Policy (25 requests). Categorization of requests, users of the services, and other information about the programs will be described. DISCUSSION/SIGNIFICANCE OF IMPACT: The navigation and onboarding services are proving to be a successful way to increase efficiency and understanding of processes and resources across the institution. Feedback from the users, coupled with high referral rates to the programs, suggests that the program is helping researchers feel better equipped with regard to their research planning, conduct, and analysis.

Current Research Approaches to Down Syndrome: Translational Research Perspectives

2020 ◽  
Vol 125 (2) ◽  
pp. 93-96
Author(s):  
George T. Capone
Keyword(s):  
Down Syndrome ◽  
Health Outcomes ◽  
Translational Research ◽  
Human Subjects ◽  
Major Theme ◽  
Medical Needs ◽  
New Therapeutic Approaches ◽  
Research Perspectives ◽  
Cell Culture Systems ◽  
Community Effort

Abstract Translational research means different things to different people. In the biomedical research community, translational research is the process of applying knowledge from basic biology and clinical trials to techniques and tools that address critical medical needs such as new therapies. Translational research then is a “bench to bedside” bridge specifically designed to improve health outcomes (Wetmore & Garner, 2010). In this sense, animal models or cell culture systems may be used to learn about basic underlying genetic and physiologic systems that are exceedingly difficult to study in human subjects (Reeves et al., 2019). This has been a major theme in Down syndrome (DS) research since the mid-1980s when mouse models that approximate the condition of trisomy 21 (Ts21) first became available (Das & Reeves 2011). Translational research has recently taken on a more expansive meaning, as the process of turning observations from the laboratory, the clinic, and the community can all lead to new therapeutic approaches to improve population health outcomes (Rubio et al., 2010). This model has received increased attention in the last decade as it is clear that improving developmental outcomes for people with DS requires a community effort on the part of all stakeholders (Capone, 2010).

scholarly journals 2518 InCHOIR learning lab: A TL1 and workforce development initiative at Mount Sinai

2018 ◽  
Vol 2 (S1) ◽  
pp. 57-57
Author(s):  
Emma K. T. Benn ◽  
Janice L. Gabrilove ◽  
Layla Fattah ◽  
Emilia Bagiella
Keyword(s):  
Translational Research ◽  
Randomized Clinical Trials ◽  
Early Stage ◽  
Added Value ◽  
Senior Faculty ◽  
Research Staff ◽  
School Of Medicine ◽  
Lecture Series ◽  
Wide Range ◽  
Mount Sinai

OBJECTIVES/SPECIFIC AIMS: Science and clinical practice are widely regarded as being complementary and synergistic. In an effort to enhance the team science, translational research capacity of the TL1 scholars at Icahn School of Medicine at Mount Sinai (ISMMS), the InCHOIR learning lab aims to provide an accessible, workforce-wide lecture series on the fundamental methods and concepts of randomized clinical trials. METHODS/STUDY POPULATION: The InCHOIR learning lab is a monthly 1 hour lecture series delivered by a range of expert clinical and translational researchers, followed by a 1 hour “Meet the Expert” session. The InCHOIR lecture series has covered a wide range of topics including, but not limited to: Decision Models; Race and Causal Inference; Innovative Strategies for Assessing Environmental Health across the Life Course; Statistics for Geneticists and Genetics for Statisticians; and From the Lab to Translation to Policy—The Neuroscience of Addiction. The “Meet the Expert” session offers TL1 predoctoral and postdoctoral scholars and KL2 scholars the opportunity to have intimate, informal discussions with experts about their career trajectories. RESULTS/ANTICIPATED RESULTS: Feedback from participants has been overwhelmingly positive. Participants have gained important insights into key topics relevant to early stage researchers. The “Meet the Expert” sessions have yielded honest and important conversations about crucial topics ranging from finding effective mentors to essential strategies for establishing a work-life balance, to overcoming adversity as underrepresented minorities and women in translational research. DISCUSSION/SIGNIFICANCE OF IMPACT: Attendance at the InCHOIR learning lab is increasing month on month, indicating the perceived need for this learning not just from early stage researchers, but also from students, senior faculty, and research staff more generally. The InChoir series provides added value through the creation of a video library, fostering new collaborations and contributing to the Icahn School of Medicine at Mount Sinai and Graduate Medical Education landscape. Priorities for the program are to increase internal visibility, in order to continue to grow attendance by MSHS students, research staff, nurses, postdoctoral fellows and residents. The program is also exploring how to engage external participation from regional CTSAs and from community advocates actively involved in community-academic research partnerships.

scholarly journals Did the Research Faculty at a Small Canadian Business School Publish in “Predatory” Venues? This Depends on the Publishing Blacklist

Publications ◽  
2019 ◽  
Vol 7 (2) ◽  
pp. 35 ◽  
Author(s):  
Panagiotis Tsigaris ◽  
Jaime A. Teixeira da Silva
Keyword(s):  
New York ◽  
Open Access ◽  
Small Business ◽  
Business School ◽  
Human Subjects ◽  
New York Times ◽  
Faculty Members ◽  
University Of Toronto ◽  
Research Faculty ◽  
Made In

The first ever quantitative paper to claim that papers published in so-called “predatory” open access (OA) journals and publishers were financially remunerated emerged from Canada. That study, published in the Journal of Scholarly Publishing (University of Toronto Press) in 2017 by Derek Pyne at Thompson Rivers University, garnered wide public and media attention, even by renowned news outlets such as The New York Times and The Economist. Pyne claimed to have found that most of the human subjects of his study had published in “predatory” OA journals, or in OA journals published by “predatory” OA publishers, as classified by Jeffrey Beall. In this paper, we compare the so-called “predatory” publications referred to in Pyne’s study with Walt Crawford’s gray open access (grayOA) list, as well as with Cabell’s blacklist, which was introduced in 2017. Using Cabell’s blacklist and Crawford’s grayOA list, we found that approximately 2% of the total publications (451) of the research faculty at the small business school were published in potentially questionable journals, contrary to the Pyne study, which found significantly more publications (15.3%). In addition, this research casts doubt to the claim made in Pyne’s study that research faculty members who have predatory publications have 4.3 “predatory” publications on average.

scholarly journals 2543

2017 ◽  
Vol 1 (S1) ◽  
pp. 54-54
Author(s):  
Jorge Delva ◽  
Adam Paberzs ◽  
Patricia Piechowski ◽  
Karen Calhoun ◽  
Diane Carr ◽  
...  
Keyword(s):  
Translational Research ◽  
Research Methods ◽  
Health Research ◽  
Governance Structure ◽  
Advisory Board ◽  
Community Advisory Board ◽  
Strategic Decisions ◽  
Study Population ◽  
Wide Community ◽  
Future Plans

OBJECTIVES/SPECIFIC AIMS: To describe how Michigan Institute for Clinical & Health Research (MICHR) has engaged communities in its leadership and governance structure. This presentation will describe these practices, how they are being evaluated, and future plans for institute-wide engagement of communities in translational research. METHODS/STUDY POPULATION: Engaged partners from various communities across Michigan in various ways within MICHR’s Community Engagement Program. RESULTS/ANTICIPATED RESULTS: MICHR has utilized participatory practices in the development of the CAB to strengthen existing relationships and build new ones with potential partners. DISCUSSION/SIGNIFICANCE OF IMPACT: MICHR-wide Community Advisory Board (CAB) will ensure community voices are heard and utilized in leadership and strategic decisions for CTSA activities.

scholarly journals Cell scientist to watch – Stefanie Redemann

2021 ◽  
Vol 134 (23) ◽  
Keyword(s):  
Cell Biology ◽  
Electron Tomography ◽  
Max Planck ◽  
Spindle Positioning ◽  
Doctorate Degree ◽  
School Of Medicine ◽  
Interdisciplinary Approaches ◽  
Approaches To Study ◽  
Virginia School ◽  
The University

ABSTRACT Stefanie Redemann studied Biology at Darmstadt Technical University, followed by a Master's at EMBL in Heidelberg, Germany. She then pursued a PhD in the labs of Tony Hyman and Jonathon Howard at the Max Planck Institute of Cell Biology and Genetics in Dresden, where she investigated the role of the actomyosin cortex in force generation and spindle positioning. After obtaining her doctorate degree in 2009, she joined the lab of Thomas Müller-Reichert at the Medical Theoretical Center in Dresden to work on reconstructing the mitotic spindle using electron tomography. Stefanie started her independent research group in 2018 at the University of Virginia School of Medicine, where she is using interdisciplinary approaches to study spindle assembly and chromosome segregation in both mitosis and meiosis.

scholarly journals Prevalence of Intestinal Parasitic Infection in Relation to Age in the Urban Population from Chandigarh, India

2021 ◽  
pp. 51-56
Author(s):  
Manjula Mehta ◽  
Sonia Bhonchal Bhardwaj ◽  
Jyoti Sharma
Keyword(s):  
Urban Population ◽  
Human Subjects ◽  
Parasitic Infection ◽  
Age Groups ◽  
Control Measures ◽  
Age Group ◽  
Intestinal Parasitic Infection ◽  
Intestinal Parasitosis ◽  
High Prevalence ◽  
Study Population

Background: Intestinal parasitic infection is a global health problem particularly in the developing countries with different prevalence rates in different regions. The aim of this study was to evaluate the prevalence of intestinal parasitic infection in different age groups in the urban population of Chandigarh, India. Materials and Methods: The retrospective study included stool samples 504 in number from human subjects from Chandigarh. Unstained wet saline mount preparations of stool sample were done to detect eggs or larvae and iodine wet mount to detect ova/ cysts of tapeworm, Enterobius, Ascaris, Giardia, Trichuris and Hookworm. Results: A high prevalence rate of intestinal parasitosis (73%) was seen. The age group distribution shows a higher prevalence of intestinal parasitic infection in the young population (age group 21-30 years and 31-40 years). Ascariasis was the most common parasitic infection observed. Conclusion: The present study reveals a high prevalence of intestinal parasitic infection in the study population and calls for long term control measures to improve their sanitary and living conditions.

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